YRC Public Data Repository - Protein Structure Prediction

Protein:	INTD_ECOLI
Organism:	Escherichia coli
Length:	387 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INTD_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|46358652, gi\|... - gi\|46358652\|ref\|YP_006360.1\| Int [Enterobacteria phage ST104], gi\|46357888\|dbj\|BAD15167.1\| Int [Ente...	229.0	[0..1]	[383..1]
gi\|62178894, gi\|... - gi\|62178894\|ref\|YP_215311.1\| hypothetical protein SC0324 [Salmonella enterica subsp. enterica serova...	227.0	[0..1]	[383..1]
gi\|24371538, gi\|... - gi\|24371538\|ref\|NP_720278.1\| Int [Enterobacteria phage ST64T], gi\|24250765\|gb\|AAL15478.1\| Int [Salmo...	227.0	[0..1]	[383..1]
gi\|62362247, gi\|... - gi\|62362247\|ref\|YP_224172.1\| gp34 [Enterobacteria phage ES18], gi\|58339090\|gb\|AAW70505.1\| gp34 [Salm...	226.0	[0..1]	[383..1]
gi\|19549014, gi\|... - gi\|2465477\|gb\|AAB72135.1\| integrase [Shigella flexneri bacteriophage V], gi\|19549014\|ref\|NP_599058.1...	225.0	[0..1]	[383..1]
gi\|56414549, gi\|... - gi\|56414549\|ref\|YP_151624.1\| integrase [Salmonella enterica subsp. enterica serovar Paratyphi A str.... gi\|197094956, gi... - gi\|197363479\|ref\|YP_002143116.1\| integrase [Salmonella enterica subsp. enterica serovar Paratyphi A ...	225.0	[0..1]	[383..1]
VINT_BPP22 - Integrase OS=Enterobacteria phage P22 GN=int PE=3 SV=1 gi\|21914435 - gi\|21914435\|gb\|AAM81400.1\|AF527608_22 Int protein [Bacteriophage P22-pbi] gi\|16209140 - gi\|16209140\|gb\|AAL09894.1\| integrase [CRIM helper plasmid pAH131] gi\|16209133 - gi\|16209133\|gb\|AAL09889.1\| integrase [CRIM helper plasmid pAH130] gi\|205339757, gi... - gi\|205339757\|gb\|EDZ26521.1\| site-specific recombinase, phage integrase family [Salmonella enterica s... gi\|194408716, gi... - gi\|194450412\|ref\|YP_002044308.1\| site-specific recombinase, phage integrase family [Salmonella enter...	225.0	[0..1]	[383..1]
gi\|24050540, gi\|... - gi\|24111756\|ref\|NP_706266.1\| putative phage integrase [Shigella flexneri 2a str. 301], gi\|24050540\|g... gi\|30040120, gi\|... - gi\|30061876\|ref\|NP_836047.1\| putative phage integrase [Shigella flexneri 2a str. 2457T], gi\|30040120...	224.0	[0..1]	[383..1]
gi\|81244258, gi\|... - gi\|82542847\|ref\|YP_406794.1\| putative phage integrase [Shigella boydii Sb227], gi\|81244258\|gb\|ABB649...	223.0	[0..1]	[383..1]
gi\|30061863, gi\|... - gi\|30061863\|ref\|NP_836034.1\| putative phage integrase [Shigella flexneri 2a str. 2457T], gi\|30040107...	223.0	[0..1]	[383..1]

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Predicted Domain #1

Region A:
Residues: [1-74]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLFRRNEIW YASYSLPGGK RIKESLGTKD KRQAQELHDK RKAELWRVEK LGDLPDVTFE  60
   61 EACLRWLEEK ADKK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.631	0.003	DNA integration	a.46.1	Methionine synthase domain
View	Download	0.739	N/A	N/A	a.112.1	Description not found.
View	Download	0.701	N/A	N/A	a.112.1	Description not found.
View	Download	0.618	N/A	N/A	a.112.1	Description not found.
View	Download	0.596	N/A	N/A	a.46.1	Methionine synthase domain

Predicted Domain #2

Region A:
Residues: [75-387]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLDSDKSRIE FWLEHFEGIR LKDISEAKIY SAVSRMHNRK TKEIWKQKVQ AAIRKGKELP  60
   61 VYEPKPVSTQ TKAKHLAMIK AILRAAERDW KWLEKAPVIK IPAVRNKRVR WLEKEEAKRL 120
  121 IDECPEPLKS VVKFALATGL RKSNIINLEW QQIDMQRRVA WVNPEESKSN RAIGVALNDT 180
  181 ACKVLRDQIG KHHKWVFVHT KAAKRADGTS TPAVRKMRID SKTSWLSACR RAGIEDFRFH 240
  241 DLRHTWASWL IQSGVPLSVL QEMGGWESIE MVRRYAHLAP NHLTEHARKI DDIFGDNVPN 300
  301 MSHSEIMEDI KKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.0
Match:	1a0pA
Description:	SITE-SPECIFIC RECOMBINASE, XERD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.32470898553998	bayes_pls_golite062009
site-specific recombinase activity	0.63725674285826	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: