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View Structure Prediction Details

Protein: INS_PANTR
Organism: Pan troglodytes
Length: 110 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INS_PANTR.

Description E-value Query
Range		 Subject
Range
INS_PONPY - Insulin OS=Pongo pygmaeus GN=INS PE=3 SV=1
 134.0 [0..1] [110..1]
INS_MACFA - Insulin OS=Macaca fascicularis GN=INS PE=3 SV=1
 133.0 [0..1] [110..1]
INS - insulin
gi|22901140 - gi|22901140|gb|AAN06935.1| insulin precursor [Gorilla gorilla]
gi|123992113, gi... - gi|61361299|gb|AAX42026.1| insulin [synthetic construct], gi|61361296|gb|AAX42025.1| insulin [synthe...
INS_GORGO - Insulin OS=Gorilla gorilla gorilla GN=INS PE=3 SV=1
 133.0 [0..1] [110..1]
gi|30584395, gi|... - gi|60653575|gb|AAX29481.1| insulin [synthetic construct], gi|60653573|gb|AAX29480.1| insulin [synthe...
 133.0 [0..1] [110..1]
INS1_RAT - Insulin-1 OS=Rattus norvegicus GN=Ins1 PE=1 SV=1
 133.0 [0..1] [110..1]
INS_CHLAE - Insulin OS=Chlorocebus aethiops GN=INS PE=1 SV=1
 133.0 [0..1] [110..1]
INS_CRILO - Insulin OS=Cricetulus longicaudatus GN=INS PE=1 SV=2
gi|305360, gi|21... - gi|305360|gb|AAA37089.1| preproinsulin, gi|2137094|pir||I48166 insulin precursor - golden hamster
 132.0 [0..1] [110..1]
INS_CHICK - Insulin OS=Gallus gallus GN=INS PE=1 SV=1
 131.0 [0..1] [110..1]
INS_PSAOB - Insulin OS=Psammomys obesus GN=INS PE=3 SV=1
 130.0 [0..1] [110..1]

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Predicted Domain #1
Region A:
Residues: [1-110] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALWMRLLPL LVLLALWGPD PASAFVNQHL CGSHLVEALY LVCGERGFFY TPKTRREAED  60
   61 LQVGQVELGG GPGAGSLQPL ALEGSLQKRG IVEQCCTSIC SLYQLENYCN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.69897
Match: 1efeA
Description: Insulin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
insulin receptor binding 5.73305521923755 bayes_pls_golite062009
receptor binding 4.68523681696587 bayes_pls_golite062009
growth factor activity 4.53461171884462 bayes_pls_golite062009
insulin-like growth factor receptor binding 4.05618549474014 bayes_pls_golite062009
binding 2.97217702905299 bayes_pls_golite062009
protein binding 2.94317823862812 bayes_pls_golite062009
hormone activity 2.72072335887093 bayes_pls_golite062009
insulin-like growth factor binding 2.70552890170172 bayes_pls_golite062009
protein complex binding 2.1188666554035 bayes_pls_golite062009
protease binding 1.89624458747028 bayes_pls_golite062009
growth factor binding 1.84573028463276 bayes_pls_golite062009
enzyme binding 0.151798820633953 bayes_pls_golite062009
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