YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: INS_CHICK
Organism: Gallus gallus
Length: 107 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INS_CHICK.

Description E-value Query
Range		 Subject
Range
INS2_XENLA - Insulin-2 OS=Xenopus laevis GN=ins-b PE=1 SV=2
 130.0 [0..1] [107..1]
INS1_RAT - Insulin-1 OS=Rattus norvegicus GN=Ins1 PE=1 SV=1
 124.0 [0..1] [107..1]
INS_LOPPI - (P01341) Insulin precursor
INS_LOPAM - Insulin OS=Lophius americanus GN=ins PE=3 SV=1
 124.0 [0..2] [107..3]
INS_PONPY - Insulin OS=Pongo pygmaeus GN=INS PE=3 SV=1
 123.0 [0..1] [107..1]
INS - insulin
gi|22901140 - gi|22901140|gb|AAN06935.1| insulin precursor [Gorilla gorilla]
gi|123992113, gi... - gi|61361299|gb|AAX42026.1| insulin [synthetic construct], gi|61361296|gb|AAX42025.1| insulin [synthe...
INS_GORGO - Insulin OS=Gorilla gorilla gorilla GN=INS PE=3 SV=1
 123.0 [0..1] [107..1]
gi|30584395, gi|... - gi|60653575|gb|AAX29481.1| insulin [synthetic construct], gi|60653573|gb|AAX29480.1| insulin [synthe...
 123.0 [0..1] [107..1]
INS_MACFA - Insulin OS=Macaca fascicularis GN=INS PE=3 SV=1
 123.0 [0..1] [107..1]
INS_CRILO - Insulin OS=Cricetulus longicaudatus GN=INS PE=1 SV=2
gi|305360, gi|21... - gi|305360|gb|AAA37089.1| preproinsulin, gi|2137094|pir||I48166 insulin precursor - golden hamster
 122.0 [0..1] [107..1]

Back

Predicted Domain #1
Region A:
Residues: [1-107] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALWIRSLPL LALLVFSGPG TSYAAANQHL CGSHLVEALY LVCGERGFFY SPKARRDVEQ  60
   61 PLVSSPLRGE AGVLPFQQEE YEKVKRGIVE QCCHNTCSLY QLENYCN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.69897
Match: 1efeA
Description: Insulin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
insulin receptor binding 5.73305521923755 bayes_pls_golite062009
receptor binding 4.68523681696587 bayes_pls_golite062009
growth factor activity 4.53461171884462 bayes_pls_golite062009
insulin-like growth factor receptor binding 4.05618549474014 bayes_pls_golite062009
binding 2.97217702905299 bayes_pls_golite062009
protein binding 2.94317823862812 bayes_pls_golite062009
hormone activity 2.72072335887093 bayes_pls_golite062009
insulin-like growth factor binding 2.70552890170172 bayes_pls_golite062009
protein complex binding 2.1188666554035 bayes_pls_golite062009
protease binding 1.89624458747028 bayes_pls_golite062009
growth factor binding 1.84573028463276 bayes_pls_golite062009
enzyme binding 0.151798820633953 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle