YRC Public Data Repository - Protein Structure Prediction

Protein:	IF2_SALTI
Organism:	Salmonella typhi
Length:	892 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IF2_SALTI.

Description	E-value	Query Range	Subject Range
IF2_ENTCL - Translation initiation factor IF-2 OS=Enterobacter cloacae GN=infB PE=3 SV=1	0.0	[1..892]	[1..897]
IF2_KLEOX - Translation initiation factor IF-2 OS=Klebsiella oxytoca GN=infB PE=3 SV=1	0.0	[1..891]	[1..895]
IF2_SALCH - Translation initiation factor IF-2 OS=Salmonella choleraesuis GN=infB PE=3 SV=1 IF2_SALCH - Translation initiation factor IF-2 OS=Salmonella choleraesuis (strain SC-B67) GN=infB PE=3 SV=1 IF2_SALCH - Translation initiation factor IF-2 OS=Salmonella choleraesuis GN=infB PE=3 SV=1	0.0	[1..892]	[1..892]
IF2_SALPA - Translation initiation factor IF-2 OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=infB PE=... IF2_SALPA - Translation initiation factor IF-2 OS=Salmonella paratyphi A GN=infB PE=3 SV=1 IF2_SALPK - Translation initiation factor IF-2 OS=Salmonella paratyphi A (strain AKU_12601) GN=infB PE=3 SV=1	0.0	[1..892]	[1..892]
IF2_SALTY - Translation initiation factor IF-2 OS=Salmonella typhimurium GN=infB PE=3 SV=2 IF2_SALTY - Translation initiation factor IF-2 OS=Salmonella typhimurium GN=infB PE=3 SV=2 IF2_SALTY - Translation initiation factor IF-2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) G... IF2_SALPB - Translation initiation factor IF-2 OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=infB P... lcl\|NC_016856.1_... - [gene=infB] [protein=translation initiation factor IF-2] [protein_id=YP_005239464.1] [location=compl... IF2_SALPC - Translation initiation factor IF-2 OS=Salmonella paratyphi C (strain RKS4594) GN=infB PE=3 SV=1 gi\|238910081 - gi\|238910081\|ref\|ZP_04653918.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... IF2_SALDC - Translation initiation factor IF-2 OS=Salmonella dublin (strain CT_02021853) GN=infB PE=3 SV=1 gi\|200388994, gi... - gi\|200388994\|ref\|ZP_03215606.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... gi\|204322405, gi... - gi\|204928083\|ref\|ZP_03219283.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... IF2_SALEP - Translation initiation factor IF-2 OS=Salmonella enteritidis PT4 (strain P125109) GN=infB PE=3 SV=1 IF2_SALHS - Translation initiation factor IF-2 OS=Salmonella heidelberg (strain SL476) GN=infB PE=3 SV=1 gi\|194457721, gi... - gi\|194471357\|ref\|ZP_03077341.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... IF2_SALPB - Translation initiation factor IF-2 OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=infB P... IF2_SALA4 - Translation initiation factor IF-2 OS=Salmonella agona (strain SL483) GN=infB PE=3 SV=1 gi\|197243574, gi... - gi\|197265319\|ref\|ZP_03165393.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... gi\|168262703, gi... - gi\|205348528\|gb\|EDZ35159.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|195633232, gi... - gi\|195633232\|gb\|EDX51646.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|205343413, gi... - gi\|205343413\|gb\|EDZ30177.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... IF2_SALNS - Translation initiation factor IF-2 OS=Salmonella newport (strain SL254) GN=infB PE=3 SV=1 gi\|205323238, gi... - gi\|205323238\|gb\|EDZ11077.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|167990149, gi... - gi\|205331232\|gb\|EDZ17996.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|205333815, gi... - gi\|205333815\|gb\|EDZ20579.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|168243120, gi... - gi\|205337921\|gb\|EDZ24685.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ...	0.0	[1..892]	[1..892]
gi\|3859102 - gi\|3859102\|emb\|CAA05549.1\| initiation factor IF2-alpha [Salmonella typhimurium] gi\|3859102\|emb\|C... - initiation factor IF2-alpha [Salmonella typhimurium]	0.0	[1..892]	[1..892]
IF2_SHISS - Translation initiation factor IF-2 OS=Shigella sonnei (strain Ss046) GN=infB PE=3 SV=1	0.0	[1..892]	[1..890]
gi\|188016401, gi... - gi\|188016401\|gb\|EDU54523.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4113... gi\|168754149, gi... - gi\|189358562\|gb\|EDU76981.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4401... gi\|168762134, gi... - gi\|189367599\|gb\|EDU86015.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4501... EG10505 - translation initiation factor IF-2 / Translation initiation factor IF-2 gi\|189361460, gi... - gi\|189361460\|gb\|EDU79879.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4486... gi\|187770883, gi... - gi\|187770883\|gb\|EDU34727.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4196... gi\|189000990, gi... - gi\|189000990\|gb\|EDU69976.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4076... gi\|124525924, gi... - gi\|124525924\|ref\|ZP_01697929.1\| translation initiation factor IF-2 [Escherichia coli B], gi\|12450202... IF2_ECOLI - Translation initiation factor IF-2 - Escherichia coli IF2_ECO5E - Translation initiation factor IF-2 OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=infB PE=3 S... IF2_ECOSE - Translation initiation factor IF-2 OS=Escherichia coli (strain SE11) GN=infB PE=3 SV=1 IF2_ECO8A - Translation initiation factor IF-2 OS=Escherichia coli O8 (strain IAI1) GN=infB PE=3 SV=1 IF2_ECO55 - Translation initiation factor IF-2 OS=Escherichia coli (strain 55989 / EAEC) GN=infB PE=3 SV=1 IF2_ECO7I - Translation initiation factor IF-2 OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=infB PE=3 SV=... IF2_ECOLU - Translation initiation factor IF-2 OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=infB P... gi\|189374161, gi... - gi\|189374161\|gb\|EDU92577.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC869]... gi\|168797769, gi... - gi\|189379615\|gb\|EDU98031.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC508]... IF2_ECODH - Translation initiation factor IF-2 OS=Escherichia coli (strain K12 / DH10B) GN=infB PE=3 SV=1 gi\|194417983, gi... - gi\|194433720\|ref\|ZP_03065995.1\| translation initiation factor IF-2 [Shigella dysenteriae 1012], gi\|1... gi\|195938388 - gi\|195938388\|ref\|ZP_03083770.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC... gi\|208727102, gi... - gi\|208807301\|ref\|ZP_03249638.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC... gi\|208813778, gi... - gi\|208813778\|ref\|ZP_03255107.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC... gi\|208818328, gi... - gi\|208818328\|ref\|ZP_03258648.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC... EG10505 - translation initiation factor IF-2 / Translation initiation factor IF-2 gi\|75239262, gi\|... - gi\|75239262\|ref\|ZP_00723233.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... gi\|193062206, gi... - gi\|75260098\|ref\|ZP_00731376.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... gi\|75513383, gi\|... - gi\|75513383\|ref\|ZP_00735807.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... IF2_ECO57 - Translation initiation factor IF-2 OS=Escherichia coli O157:H7 GN=infB PE=3 SV=1 gi\|89109933, gi\|... - gi\|89109933\|ref\|AP_003713.1\| fused protein chain initiation factor 2, IF2 [Escherichia coli str. K-1... gi\|13363522, gi\|... - gi\|15833303\|ref\|NP_312076.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. Sakai... IF2_ECOLC - Translation initiation factor IF-2 OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=inf... IF2_ECOBW - Translation initiation factor IF-2 OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=infB PE=3 S... gi\|251786440, gi... - gi\|251786440\|ref\|YP_003000744.1\| hypothetical protein B21_02986 [Escherichia coli BL21], gi\|24237871... gi\|254289862, gi... - gi\|254289862\|ref\|YP_003055610.1\| translation initiation factor IF-2 [Escherichia coli BL21(DE3)], gi... gi\|226839958, gi... - gi\|254038334\|ref\|ZP_04872392.1\| translation initiation factor IF-2 [Escherichia sp. 1_1_43], gi\|2268... gi\|253975013, gi... - gi\|254163112\|ref\|YP_003046220.1\| translation initiation factor IF-2 [Escherichia coli B str. REL606]... gi\|254594519, gi... - gi\|254795119\|ref\|YP_003079956.1\| protein chain initiation factor 2, IF2 [Escherichia coli O157:H7 st... gi\|83585809, gi\|... - gi\|83585809\|ref\|ZP_00924450.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... IF2_ECO24 - Translation initiation factor IF-2 OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=infB PE=3... IF2_ECOHS - Translation initiation factor IF-2 OS=Escherichia coli O9:H4 (strain HS) GN=infB PE=3 SV=1 gi\|75211119, gi\|... - gi\|75211119\|ref\|ZP_00711232.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... gi\|75228773, gi\|... - gi\|75228773\|ref\|ZP_00715382.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ...	0.0	[1..892]	[1..890]
gi\|227887891, gi... - gi\|227887891\|ref\|ZP_04005696.1\| translation initiation factor IF-2 [Escherichia coli 83972], gi\|2278... gi\|226899119, gi... - gi\|237706079\|ref\|ZP_04536560.1\| translation initiation factor IF-2 [Escherichia sp. 3_2_53FAA], gi\|2... IF2_ECO45 - Translation initiation factor IF-2 OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=infB PE=3 SV=1 IF2_ECO27 - Translation initiation factor IF-2 OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=infB PE=3... sp\|B7UJ63\|IF2_ECO27 - Translation initiation factor IF-2 OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=infB PE=3... IF2_ECOK1 - Translation initiation factor IF-2 OS=Escherichia coli O1:K1 / APEC GN=infB PE=3 SV=1 IF2_ECOL6 - Translation initiation factor IF-2 OS=Escherichia coli O6 GN=infB PE=3 SV=1 IF2_ECOUT - Translation initiation factor IF-2 OS=Escherichia coli (strain UTI89 / UPEC) GN=infB PE=3 SV=1 gi\|75240807, gi\|... - gi\|75240807\|ref\|ZP_00724705.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... IF2_ECOL6 - Translation initiation factor IF-2 OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN... gi\|2597877, gi\|2... - gi\|2597877\|emb\|CAA05541.1\| Initiation factor IF2-alpha [Escherichia coli], gi\|2597873\|emb\|CAA05538.1... IF2_ECOL5 - Translation initiation factor IF-2 OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=infB PE=3 S...	0.0	[1..892]	[1..890]
IF2_SHIDS - Translation initiation factor IF-2 OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=infB PE=3 SV...	0.0	[1..892]	[1..890]

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Predicted Domain #1

Region A:
Residues: [1-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDLTLKALA AERQVSVDRL VQQFADAGIR KSADDSVSAQ EKQTLLAHLN REAVSGPDKL  60
   61 TLQRKTRSTL NIPGTGGKSK SVQIEVRKKR TFVKRDPQEA ERLAAEEQAQ REAEEQARRE 120
  121 AEEQAKREAQ QKAEREAAEQ AKREAAEKAK REAAEKDKVS NQQTDDMTKT AQAEKARREN 180
  181 EAAELKRKAE EEARRKLEEE ARRVAEEARR MAEENKWTAT PEPVEDTSDY HVTTSQHARQ 240
  241 AEDENDREVE GGRGRGRNAK AARPAKKGKH AESKADR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.39794
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [278-385]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEARAAVRGG KGGKRKGSSL QQGFQKPAQA VNRDVVIGET ITVGELANKM AVKGSQVIKA  60
   61 MMKLGAMATI NQVIDQETAQ LVAEEMGHKV ILRRENELEE AVMSDRDT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.0
Match:	2e87A
Description:	No description for 2e87A was found.

Predicted Domain #3

Region A:
Residues: [386-892]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAAAEPRAPV VTIMGHVDHG KTSLLDYIRS TKVASGEAGG ITQHIGAYHV ETDNGMITFL  60
   61 DTPGHAAFTS MRARGAQATD IVVLVVAADD GVMPQTIEAI QHAKAAGVPV VVAVNKIDKP 120
  121 EADPDRVKNE LSQYGILPEE WGGESQFVHV SAKAGTGIDE LLDAILLQAE VLELKAVRKG 180
  181 MASGAVIESF LDKGRGPVAT VLVREGTLHK GDIVLCGFEY GRVRAMRNEL GQEVLEAGPS 240
  241 IPVEILGLSG VPAAGDEVTV VRDEKKAREV ALYRQGKFRE VKLARQQKSK LENMFVNMTE 300
  301 GEVHEVNIVL KADVQGSVEA ISDSLLKLST DEVKVKIIGS GVGGITETDA TLAAASNAIL 360
  361 VGFNVRADAS ARKVIESESL DLRYYSVIYN LIDEVKAAMS GMLSPELKQQ IIGLAEVRDV 420
  421 FKSPKFGAIA GCMVTEGTIK RHNPIRVLRD NVVIYEGELE SLRRFKDDVN EVRNGMECGI 480
  481 GVKNYNDVRV GDMIEVFEII EIQRTIA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	127.0
Match:	1zo1I
Description:	IF2, IF1, and tRNA fitted to cryo-EM data OF E. COLI 70S initiation complex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits