YRC Public Data Repository - Protein Structure Prediction

Protein:	HYDN_ECOLI
Organism:	Escherichia coli
Length:	175 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HYDN_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|148655927, gi... - gi\|148655927\|ref\|YP_001276132.1\| 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein [Ro...	159.0	[0..2]	[174..3]
gi\|68512319, gi\|... - gi\|68561487\|ref\|ZP_00600782.1\| 4Fe-4S ferredoxin, iron-sulfur binding:Polysulphide reductase, NrfD [...	158.0	[0..2]	[174..3]
gi\|71282673, gi\|... - gi\|71482494\|ref\|ZP_00662180.1\| 4Fe-4S ferredoxin, iron-sulfur binding:Polysulphide reductase, NrfD [...	158.0	[0..1]	[171..22]
gi\|189339739, gi... - gi\|67918570\|ref\|ZP_00512166.1\| 4Fe-4S ferredoxin, iron-sulfur binding:Polysulphide reductase, NrfD [...	156.0	[0..1]	[169..1]
gi\|94970030, gi\|... - gi\|94970030\|ref\|YP_592078.1\| Fe-S-cluster-containing hydrogenase [Candidatus Koribacter versatilis E...	154.0	[0..2]	[170..775]
gi\|119353318, gi... - gi\|67936163\|ref\|ZP_00529175.1\| 4Fe-4S ferredoxin, iron-sulfur binding:Polysulphide reductase, NrfD [...	154.0	[0..1]	[169..1]
gi\|85773734, gi\|... - gi\|86157223\|ref\|YP_464008.1\| 4Fe-4S ferredoxin, iron-sulfur binding protein [Anaeromyxobacter dehalo...	153.0	[0..2]	[171..752]
gi\|76164515, gi\|... - gi\|76260598\|ref\|ZP_00768231.1\| 4Fe-4S ferredoxin, iron-sulfur binding:Polysulphide reductase, NrfD [...	153.0	[0..2]	[173..3]
gi\|78165820, gi\|... - gi\|78185918\|ref\|YP_373961.1\| Fe-S-cluster-containing hydrogenase components 1-like [Pelodictyon lute...	152.0	[0..1]	[171..1]

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Predicted Domain #1

Region A:
Residues: [1-175]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRFIIADAS KCIGCRTCEV ACVVSHQENQ DCASLTPETF LPRIHVIKGV NISTATVCRQ  60
   61 CEDAPCANVC PNGAISRDKG FVHVMQERCI GCKTCVVACP YGAMEVVVRP VIRNSGAGLN 120
  121 VRADKAEANK CDLCNHREDG PACMAACPTH ALICVDRNKL EQLSAEKRRR TALMF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.522879
Match:	1kqfB
Description:	Formate dehydrogenase N, iron-sulfur (beta) subunit; Iron-sulfur subunit of formate dehydrogenase N, transmembrane anchor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4 iron, 4 sulfur cluster binding	7.27554333181693	bayes_pls_golite062009
iron-sulfur cluster binding	6.49651154487804	bayes_pls_golite062009
metal cluster binding	6.49651154487804	bayes_pls_golite062009
formate dehydrogenase activity	4.7946737640663	bayes_pls_golite062009
NADH dehydrogenase activity	3.13953145151561	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	2.76338281383262	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	2.70037803782769	bayes_pls_golite062009
electron carrier activity	2.45164586846912	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	2.09041948600744	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.80621486978907	bayes_pls_golite062009
oxidoreductase activity	0.660370448422897	bayes_pls_golite062009
catalytic activity	0.488483980994331	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0827182678048914	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: