YRC Public Data Repository - Protein Structure Prediction

Protein:	HYCF_ECOLI
Organism:	Escherichia coli
Length:	180 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HYCF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|237706657, gi... - gi\|237706657\|ref\|ZP_04537138.1\| formate hydrogenlyase subunit 6 [Escherichia sp. 3_2_53FAA], gi\|2268... gi\|227834527, gi... - gi\|227888258\|ref\|ZP_04006063.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli ... gi\|170765966, gi... - gi\|170765966\|ref\|ZP_02900777.1\| formate hydrogenlyase, subunit F [Escherichia albertii TW07627], gi\|... gi\|218428408, gi... - gi\|218690844\|ref\|YP_002399056.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli... gi\|26109526, gi\|... - gi\|26249119\|ref\|NP_755159.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli CFT... gi\|91212080, gi\|... - gi\|91212080\|ref\|YP_542066.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli UTI... gi\|115514076, gi... - gi\|117624952\|ref\|YP_853940.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli AP...	123.0	[0..1]	[180..1]
gi\|190908291, gi... - gi\|75241664\|ref\|ZP_00725501.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta... gi\|110642843, gi... - gi\|110642843\|ref\|YP_670573.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli 53...	123.0	[0..1]	[180..1]
gi\|82778087, gi\|... - gi\|82778087\|ref\|YP_404436.1\| formate hydrogenlyase complex iron-sulfur subunit [Shigella dysenteriae...	122.0	[0..1]	[180..1]
gi\|189372135, gi... - gi\|189372135\|gb\|EDU90551.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC869], ... gi\|189377500, gi... - gi\|189377500\|gb\|EDU95916.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC508], ... gi\|169753962, gi... - gi\|170019034\|ref\|YP_001723988.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli... gi\|195938470 - gi\|195938470\|ref\|ZP_03083852.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli ... gi\|254594060, gi... - gi\|254794660\|ref\|YP_003079497.1\| formate hydrogenlyase complex iron-sulfur protein [Escherichia coli... gi\|208805909, gi... - gi\|208805909\|ref\|ZP_03248246.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC42... gi\|253974552, gi... - gi\|254162651\|ref\|YP_003045759.1\| formate hydrogenlyase complex iron-sulfur protein [Escherichia coli... gi\|208734990, gi... - gi\|208813713\|ref\|ZP_03255042.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC40... gi\|254037759, gi... - gi\|254037759\|ref\|ZP_04871817.1\| formate hydrogenlyase [Escherichia sp. 1_1_43], gi\|226839383\|gb\|EEH7... gi\|208818938, gi... - gi\|208818938\|ref\|ZP_03259258.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC40... gi\|254289412, gi... - gi\|254289412\|ref\|YP_003055160.1\| formate hydrogenlyase complex iron-sulfur protein [Escherichia coli... gi\|209396172, gi... - gi\|209396172\|ref\|YP_002272183.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC4... gi\|242378277, gi... - gi\|251786004\|ref\|YP_003000308.1\| hypothetical protein B21_02535 [Escherichia coli BL21], gi\|24237827... gi\|13363047, gi\|... - gi\|15832830\|ref\|NP_311603.1\| hydrogenase 4 Fe-S subunit [Escherichia coli O157:H7], gi\|13363047\|dbj\|... gi\|73856764, gi\|... - gi\|74313287\|ref\|YP_311706.1\| formate hydrogenlyase complex iron-sulfur subunit [Shigella sonnei Ss04... gi\|168749955, gi... - gi\|188015821\|gb\|EDU53943.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC4113],... gi\|209761904, gi... - pir\|\|G85920 formate hydrogenlyase subunit-7 component F [imported] - Escherichia coli (strain O157:H... gi\|82545205, gi\|... - gi\|82545205\|ref\|YP_409152.1\| formate hydrogenlyase complex iron-sulfur subunit [Shigella boydii Sb22... gi\|189357266, gi... - gi\|189357266\|gb\|EDU75685.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC4401],... gi\|189366888, gi... - gi\|189366888\|gb\|EDU85304.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC4501],... gi\|15803237, gi\|... - gi\|15803237\|ref\|NP_289269.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli O15... gi\|168768811, gi... - gi\|189362055\|gb\|EDU80474.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC4486],... gi\|187769586, gi... - gi\|187769586\|gb\|EDU33430.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC4196],... gi\|168778702, gi... - gi\|189003527\|gb\|EDU72513.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC4076],... gi\|194438985, gi... - gi\|83585621\|ref\|ZP_00924264.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta... gi\|157067846, gi... - gi\|75196695\|ref\|ZP_00706765.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta... gi\|13363047, gi\|... - gi\|15832830\|ref\|NP_311603.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli O15... gi\|110616201, gi... - gi\|110806653\|ref\|YP_690173.1\| formate hydrogenlyase complex iron-sulfur subunit [Shigella flexneri 5... gi\|75256922, gi\|... - gi\|75256922\|ref\|ZP_00728498.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta... gi\|75512370, gi\|... - gi\|75512370\|ref\|ZP_00734922.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta... gi\|75210921, gi\|... - gi\|75210921\|ref\|ZP_00711045.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta... gi\|190903197, gi... - gi\|75230074\|ref\|ZP_00716584.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta... gi\|217327035, gi... - gi\|217327035\|ref\|ZP_03443118.1\| formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. TW14... gi\|218355313, gi... - gi\|218547772\|ref\|YP_002381563.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia ferg... gi\|124528086, gi... - gi\|124528086\|ref\|ZP_01699439.1\| 4Fe-4S ferredoxin, iron-sulfur binding domain protein [Escherichia c...	122.0	[0..1]	[180..1]
gi\|167550312, gi... - gi\|205324749\|gb\|EDZ12588.1\| formate hydrogenlyase, subunit F [Salmonella enterica subsp. enterica se... gi\|16503926, gi\|... - gi\|25324256\|pir\|\|AD0846 formate hydrogenlyase chain 6 [imported] - Salmonella enterica subsp. enteri... gi\|205327931, gi... - gi\|205327931\|gb\|EDZ14695.1\| formate hydrogenlyase, subunit F [Salmonella enterica subsp. enterica se... gi\|205334623, gi... - gi\|205334623\|gb\|EDZ21387.1\| formate hydrogenlyase, subunit F [Salmonella enterica subsp. enterica se... gi\|168464026, gi... - gi\|195633645\|gb\|EDX52059.1\| formate hydrogenlyase, subunit F [Salmonella enterica subsp. enterica se... gi\|16761625 - gi\|16761625\|ref\|NP_457242.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enterica ... gi\|16766154, gi\|... - gi\|16766154\|ref\|NP_461769.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella typhimuri... gi\|29143109, gi\|... - gi\|29143109\|ref\|NP_806451.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enterica ... gi\|161365115, gi... - gi\|161615751\|ref\|YP_001589716.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enter... lcl\|NC_016856.1_... - [gene=hycF] [protein=formate hydrogenlyase complex iron-sulfur subunit] [protein_id=YP_005238952.1] ... gi\|213583851 - gi\|213583851\|ref\|ZP_03365677.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enteri... gi\|213610077 - gi\|213610077\|ref\|ZP_03369903.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enteri... gi\|213648117 - gi\|213648117\|ref\|ZP_03378170.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enteri... gi\|213999451 - gi\|213999451\|ref\|ZP_03410186.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enteri... gi\|205353792, gi... - gi\|205353792\|ref\|YP_002227593.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enter... gi\|206709914, gi... - gi\|207858111\|ref\|YP_002244762.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enter... gi\|213052198 - gi\|213052198\|ref\|ZP_03345076.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enteri... gi\|213426141 - gi\|213426141\|ref\|ZP_03358891.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enteri... gi\|205342812, gi... - gi\|205342812\|gb\|EDZ29576.1\| formate hydrogenlyase, subunit F [Salmonella enterica subsp. enterica se... gi\|194458034, gi... - gi\|194471670\|ref\|ZP_03077654.1\| formate hydrogenlyase, subunit F [Salmonella enterica subsp. enteric... gi\|198243506, gi... - gi\|198243506\|ref\|YP_002216820.1\| formate hydrogenlyase, subunit F [Salmonella enterica subsp. enteri... gi\|200388107, gi... - gi\|200388107\|ref\|ZP_03214719.1\| formate hydrogenlyase, subunit F [Salmonella enterica subsp. enteric...	122.0	[0..1]	[178..1]
gi\|194418704, gi... - gi\|83569917\|ref\|ZP_00921365.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta...	122.0	[0..1]	[180..1]
gi\|157157477, gi... - gi\|75187442\|ref\|ZP_00700709.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta... gi\|218696314, gi... - gi\|218696314\|ref\|YP_002403981.1\| formate hydrogenlyase complex iron-sulfur subunit [Escherichia coli...	121.0	[0..1]	[180..1]
gi\|62181351, gi\|... - gi\|62181351\|ref\|YP_217768.1\| formate hydrogenlyase complex iron-sulfur subunit [Salmonella enterica ...	121.0	[0..1]	[178..1]
gi\|192957062, gi... - gi\|75235685\|ref\|ZP_00719859.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta...	121.0	[0..1]	[180..1]
gi\|187428214, gi... - gi\|75176420\|ref\|ZP_00696564.1\| COG1143: Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreducta...	120.0	[0..1]	[180..1]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTFIKKVIK TGTATSSYPL EPIAVDKNFR GKPEQNPQQC IGCAACVNAC PSNALTVETD  60
   61 LATGELAWEF NLGHCIFCGR CEEVCPTAAI KLSQEYELAV WKKEDFLQQS RFALCN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.0
Match:	2fug9
Description:	Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [117-180]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CRVCNRPFAV QKEIDYAIAL LKHNGDSRAE NHRESFETCP ECKRQKCLVP SDRIELTRHM  60
   61 KEAI

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	0.973
Match:	2ct2A
Description:	Solution Structure of the RING domain of the Tripartite motif protein 32
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits