YRC Public Data Repository - Protein Structure Prediction

Protein:	HYAF_ECOLI
Organism:	Escherichia coli
Length:	285 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HYAF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|75240594, gi\|... - gi\|75240594\|ref\|ZP_00724511.1\| hypothetical protein EcolF_01002312 [Escherichia coli F11], gi\|191172...	402.0	[0..1]	[285..133]
gi\|75255603, gi\|... - gi\|75255603\|ref\|ZP_00727387.1\| hypothetical protein EcolE2_01004370 [Escherichia coli E22], gi\|19306... gi\|194429848, gi... - gi\|75208929\|ref\|ZP_00709202.1\| hypothetical protein EcolB_01003872 [Escherichia coli B171], gi\|19442...	400.0	[0..1]	[285..1]
gi\|187733770, gi... - gi\|75175463\|ref\|ZP_00695683.1\| hypothetical protein SboyB_01004472 [Shigella boydii BS512], gi\|18773... gi\|30040761, gi\|... - gi\|30062515\|ref\|NP_836686.1\| hydrogenase-1 operon protein hyaF [Shigella flexneri 2a str. 2457T], gi...	399.0	[0..1]	[285..1]
gi\|117623186, gi... - gi\|117623186\|ref\|YP_852099.1\| hydrogenase-1 operon protein HyaF [Escherichia coli APEC O1], gi\|11551...	399.0	[0..1]	[285..21]
gi\|110641166, gi... - gi\|110641166\|ref\|YP_668896.1\| hydrogenase-1 operon protein HyaF [Escherichia coli 536], gi\|110342758...	399.0	[0..1]	[285..1]
gi\|74311533, gi\|... - gi\|74311533\|ref\|YP_309952.1\| nickel incorporation into hydrogenase-1 proteins [Shigella sonnei Ss046...	398.0	[0..1]	[285..1]
gi\|26247003, gi\|... - gi\|26247003\|ref\|NP_753043.1\| hydrogenase-1 operon protein HyaF [Escherichia coli CFT073], gi\|2610740... gi\|227884064, gi... - gi\|227884064\|ref\|ZP_04001869.1\| hydrogenase-1 operon protein HyaF [Escherichia coli 83972], gi\|22783...	398.0	[0..1]	[285..1]
gi\|83570616, gi\|... - gi\|83570616\|ref\|ZP_00922060.1\| hypothetical protein Sdys1_01001241 [Shigella dysenteriae 1012], gi\|1...	398.0	[0..1]	[285..1]
gi\|91210074, gi\|... - gi\|91210074\|ref\|YP_540060.1\| hydrogenase-1 operon protein HyaF [Escherichia coli UTI89], gi\|91071648... gi\|218364644, gi... - gi\|218557875\|ref\|YP_002390788.1\| protein involved in nickel incorporation into hydrogenase-1 protein... gi\|237707038, gi... - gi\|237707038\|ref\|ZP_04537519.1\| hydrogenase-1 operon protein HyaF [Escherichia sp. 3_2_53FAA], gi\|22...	397.0	[0..1]	[285..1]
gi\|81246111, gi\|... - gi\|82544700\|ref\|YP_408647.1\| HyaF [Shigella boydii Sb227], gi\|81246111\|gb\|ABB66819.1\| HyaF [Shigella...	397.0	[0..1]	[285..1]

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Predicted Domain #1

Region A:
Residues: [1-103]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSETFFHLLG PGTQPNDDSF SMNPLPITCQ VNDEPSMAAL EQCAHSPQVI ALLNELQHQL  60
   61 SERQPPLGEV LAVDLLNLNA DDRHFINTLL GEGEVSVRIQ QAD

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.383	0.062	nickel ion binding	a.74.1	Cyclin-like
View	Download	0.568	0.028	nickel ion binding	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain
View	Download	0.459	N/A	N/A	c.25.1	Ferredoxin reductase-like, C-terminal NADP-linked domain
View	Download	0.456	N/A	N/A	c.58.1	Aminoacid dehydrogenase-like, N-terminal domain
View	Download	0.445	N/A	N/A	c.58.1	Aminoacid dehydrogenase-like, N-terminal domain

Predicted Domain #2

Region A:
Residues: [104-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSESEIQEAI FCGLWRVRRR RGEKLLEDKL EAGCAPLALW QAATQNLLPT DSLLPPPIDG  60
   61 LMNGLPLAHE LLAHVRNPDA QPHSINLTQL PISEADRLFL SRLCGPGNIQ IRTIGYGESY 120
  121 INATGLRHVW HLRCTDTLKG PLLESYEICP IPEVVLAAPE DLVDSAQRLS EVCQWLAEAA 180
  181 PT

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	71.327902
Match:	PF04809.4
Description:	No description for PF04809.4 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits