YRC Public Data Repository - Protein Structure Prediction

Protein:	HSCB_ECOLI
Organism:	Escherichia coli
Length:	171 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSCB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|22298332, gi\|... - gi\|22298332\|ref\|NP_681579.1\| heat shock protein [Thermosynechococcus elongatus BP-1], gi\|22294511\|db...	144.0	[0..2]	[134..6]
DNAJ_SYNEL - Chaperone protein dnaJ OS=Synechococcus elongatus GN=dnaJ PE=3 SV=2 DNAJ_THEEB - Chaperone protein DnaJ OS=Thermosynechococcus elongatus (strain BP-1) GN=dnaJ PE=3 SV=2	144.0	[0..2]	[134..4]
gi\|82703356, gi\|... - gi\|82703356\|ref\|YP_412922.1\| heat shock protein DnaJ [Nitrosospira multiformis ATCC 25196], gi\|82411...	142.0	[0..2]	[134..14]
DNAJ_ROSS1 - Chaperone protein DnaJ OS=Roseiflexus sp. (strain RS-1) GN=dnaJ PE=3 SV=1	141.0	[0..2]	[133..6]
gi\|85722654, gi\|... - gi\|85859563\|ref\|YP_461765.1\| chaperone protein dnaJ [Syntrophus aciditrophicus SB], gi\|85722654\|gb\|A...	141.0	[0..2]	[136..26]
DNAJ_CARHZ - Chaperone protein DnaJ OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901...	141.0	[0..2]	[138..4]
gi\|94676848, gi\|... - gi\|94676848\|ref\|YP_588982.1\| chaperone protein DnaJ [Baumannia cicadellinicola str. Hc (Homalodisca ...	141.0	[0..2]	[132..5]
gi\|222525487, gi... - gi\|222525487\|ref\|YP_002569958.1\| chaperone protein DnaJ [Chloroflexus sp. Y-400-fl], gi\|222449366\|gb... gi\|163668919, gi... - gi\|76258836\|ref\|ZP_00766489.1\| Heat shock protein DnaJ [Chloroflexus aurantiacus J-10-fl], gi\|761662...	140.0	[0..2]	[133..8]
DNAJ_METTE - Chaperone protein DnaJ OS=Methanosarcina thermophila GN=dnaJ PE=3 SV=1 gi\|5824078\|emb\|C... - heat shock protein 40(DnaJ) [Methanosarcina thermophila]	139.0	[0..2]	[139..6]
gi\|159121067, gi... - gi\|94493199\|ref\|ZP_01300403.1\| hypothetical protein Rgryl_01001032 [Rickettsiella grylli], gi\|160872...	138.0	[0..2]	[134..6]

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Predicted Domain #1

Region A:
Residues: [1-171]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYFTLFGLP ARYQLDTQAL SLRFQDLQRQ YHPDKFASGS QAEQLAAVQQ SATINQAWQT  60
   61 LRHPLMRAEY LLSLHGFDLA SEQHTVRDTA FLMEQLELRE ELDEIEQAKD EARLESFIKR 120
  121 VKKMFDTRHQ LMVEQLDNET WDAAADTVRK LRFLDKLRSS AEQLEEKLLD F

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.522879
Match:	1fpoA
Description:	HSC20 (HSCB), N-terminal (J) domain; HSC20 (HSCB), C-terminal oligomerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
unfolded protein binding	1.88951904547892	bayes_pls_golite062009
heat shock protein binding	1.07912272496937	bayes_pls_golite062009
binding	0.698924774911916	bayes_pls_golite062009
chaperone binding	0.66250965400414	bayes_pls_golite062009
protein binding	0.638532996829248	bayes_pls_golite062009
catalytic activity	0.47742884460637	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: