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View Structure Prediction Details

Protein: hdc-PC
Organism: Drosophila melanogaster
Length: 1080 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hdc-PC.

Description E-value Query
Range
Subject
Range
gi|6065831 - gi|6065831|emb|CAB58233.1| headcase protein [Drosophila melanogaster]
1049.0 [0..1] [1080..1]

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Predicted Domain #1
Region A:
Residues: [1-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPRRNSNIS SSGNSTQQQH QQQLQQQHQT QQHQLLQFYA ENVNSSGVLM APMQGTGGVG  60
   61 GVGGGGMVHC CLPSGDCRKL DTLIHLNELS LADCIRVLCN NENCSAGQYM HRECFEWWEA 120
  121 SVLQALKANG RARSWSERQR LQHLWTKKGY ELVQKACSCK CGRGQLRKDL DWVPPSSQGV 180
  181 IYLNGSGNRP TLANGSLSED DDKKKAKKKR NRNNNNNNGG GGGGGAGVNG NTKTPLSNNN 240
  241 GNSYAGLTPN PNVGVIGSGL PHNNGNTASN GSSGNNGS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [279-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGVLQTSALA TFSNILNTNN VLGLDLRARA GSLSSSGAGS GSTSPSDSQS SGEISVSPVQ  60
   61 QLLPQQQQQQ QQSLLIQPLG PAFGSNLLQN GLGLSKNLLI APQQQQQQQL QQQQQQQNNL 120
  121 PALANISNFK PLASYEQQQL VQQQKNK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [426-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVELYSDRVR STSGCNGIFS RRLDFSSFNL LPKTRLNSYQ VKIEDEGNHG NDETRLFILS  60
   61 SLAQSQMSRV ACILCEEPLL VFDRY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [511-645]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLVDGSFFLS PKQHSSGCIE VKYEGRTLYL TCVCMSCLDG TSSSRAINCR FCKEPWDGSS  60
   61 LVLGTMYAYD IFAAMPCCAE RFKCNNCFKM LMHPQQRLSF YSDYSHGVTC PYCNTQDTHF 120
  121 VKPLTFCYAK TTATR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.03
Match: 2dfyX
Description: No description for 2dfyX was found.

Predicted Domain #5
Region A:
Residues: [646-960]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPTLAXHEAP LESPVGTGAT TTQVPNAQGS PTASGCSSNT IASKQPPKQP LYNAAIDYSA  60
   61 PLQQQINPDL IGAHPHAQQH QQQVRQQQQQ QQQQQPQQQQ QQQQQQTQQQ QSQQQQQQQQ 120
  121 QQHQPVVSTF QRGNFPQQSH KTMNMMAMAD VMSKYQQQQH QQQQQQRQQQ HNLQPQQQHA 180
  181 TQKGLEGLLL TNTNTSNNNS SSSSSSSISN LIISHNSASN TGNKMQPTWG QSDAISALWG 240
  241 CSSSSSGCSS GSGSQPSLSP TASSNGNDGS KMMLWAAQSS PQNAATLRDG FKELQRQQPP 300
  301 QQQVPQQQPH AASPT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [961-1080]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASLTSSSSSS NGWSASHYGK PNIWELPGST GQRTPASSHD IFTDLLCNLS ISQDNSSQQA  60
   61 SSKADASDVS SNSSSSAGEL LEAANIWRFP EYASSQLYME EPTGGAAACM QLFNDYLNMN 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle