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View Structure Prediction Details

Protein: HBB_VULVU
Organism: Vulpes vulpes
Length: 146 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HBB_VULVU.

Description E-value Query
Range		 Subject
Range
gi|73988393 - gi|73988393|ref|XP_542374.2| PREDICTED: similar to Hemoglobin epsilon chain [Canis familiaris]
 196.0 [0..1] [146..46]
HBG_MACNE - Hemoglobin subunit gamma OS=Macaca nemestrina GN=HBG PE=1 SV=1
 193.0 [0..2] [146..2]
gi|1360668, gi|3... - gi|38088|emb|CAA37498.1| gamma-globin-2(A) [Macaca mulatta], gi|342109|gb|AAA36845.1| gamma-globin, ...
 193.0 [0..2] [146..3]
HBG2_HYLLA - Hemoglobin subunit gamma-2 OS=Hylobates lar GN=HBG2 PE=2 SV=2
 193.0 [0..2] [146..3]
gi|183885 - gi|183885|gb|AAB50159.1| hemoglobin gamma-G [Homo sapiens]
 193.0 [0..2] [146..8]
HBG1_PONPY - Hemoglobin subunit gamma-1 OS=Pongo pygmaeus GN=HBG1 PE=2 SV=2
 192.0 [0..2] [146..3]
HBB_ANAPP - Hemoglobin subunit beta OS=Anas platyrhynchos platyrhynchos GN=HBB PE=1 SV=1
 192.0 [0..1] [146..1]
HBB_COLLI - Hemoglobin subunit beta OS=Columba livia GN=HBB PE=1 SV=1
 192.0 [0..1] [146..1]

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Predicted Domain #1
Region A:
Residues: [1-146] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VHLTAEEKSL VTGLWGKVNV DEVGGEALGR LLIVYPWTQR FFDSFGDLST PDAVMGNAKV  60
   61 KAHGKKVLNS FSDGLKNLDN LKGTFAKLSE LHCDKLHVDP ENFKLLGNVL VCVLAHHFGK 120
  121 EFTPQVQAAY QKVVAGVANA LAHKYH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.39794
Match: 1j7wB
Description: Hemoglobin, beta-chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxygen transporter activity 12.7518923261978 bayes_pls_golite062009
hemoglobin binding 7.80994828423656 bayes_pls_golite062009
oxygen binding 7.60582561525971 bayes_pls_golite062009
hemoglobin alpha binding 6.6133698394882 bayes_pls_golite062009
organic acid binding 4.76461807092667 bayes_pls_golite062009
hemoglobin beta binding 3.70103281638942 bayes_pls_golite062009
transporter activity 2.30531874940611 bayes_pls_golite062009
substrate-specific transporter activity 2.13533596372692 bayes_pls_golite062009
binding 1.61998555357457 bayes_pls_golite062009
protein binding 1.50013290504406 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 0.436801914510671 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle