YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254291588, gi...
Organism:	Vibrio cholerae AM-19226
Length:	246 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254291588, gi....

Description	E-value	Query Range	Subject Range
CMOA_ACTSZ - Carboxy-S-adenosyl-L-methionine synthase OS=Actinobacillus succinogenes (strain ATCC 55618 / 130Z) G...	182.0	[0..7]	[246..2]
CMOA_VIBPA - Carboxy-S-adenosyl-L-methionine synthase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210... CMOA_VIBPA - tRNA (cmo5U34)-methyltransferase OS=Vibrio parahaemolyticus GN=cmoA PE=3 SV=1 gi\|149748079, gi... - gi\|153838512\|ref\|ZP_01991179.1\| methyltransferase, putative [Vibrio parahaemolyticus AQ3810], gi\|149...	179.0	[0..6]	[246..5]
gi\|116183205, gi... - gi\|75853618\|ref\|ZP_00761419.1\| COG0500: SAM-dependent methyltransferases [Vibrio sp. Ex25], gi\|11618...	178.0	[0..6]	[246..5]
gi\|91228189, gi\|... - gi\|91228189\|ref\|ZP_01262171.1\| hypothetical protein V12G01_20578 [Vibrio alginolyticus 12G01], gi\|91...	177.0	[0..6]	[246..5]
gi\|116188959, gi... - gi\|75830108\|ref\|ZP_00759392.1\| COG0500: SAM-dependent methyltransferases [Vibrio cholerae MO10], gi\|... gi\|75814497 - gi\|75814497\|ref\|ZP_00745078.1\| COG0500: SAM-dependent methyltransferases [Vibrio cholerae V52] gi\|75826516 - gi\|75826516\|ref\|ZP_00755951.1\| COG0500: SAM-dependent methyltransferases [Vibrio cholerae O395] tr\|A0A085QI64\|A0... - tRNA (cmo5U34)-methyltransferase OS=Vibrio cholerae GN=cmoA PE=3 SV=1	177.0	[0..5]	[246..1]
CMOA_PHOPR - Carboxy-S-adenosyl-L-methionine synthase OS=Photobacterium profundum (strain SS9) GN=cmoA PE=3 SV=1 CMOA_PHOPR - tRNA (cmo5U34)-methyltransferase OS=Photobacterium profundum GN=cmoA PE=3 SV=1	177.0	[0..3]	[246..1]
gi\|37199222, gi\|... - gi\|37680474\|ref\|NP_935083.1\| hypothetical protein VV2290 [Vibrio vulnificus YJ016], gi\|37199222\|dbj\|...	176.0	[0..6]	[246..7]
gi\|90411658, gi\|... - gi\|90411658\|ref\|ZP_01219668.1\| hypothetical protein P3TCK_16384 [Photobacterium profundum 3TCK], gi\|...	176.0	[0..5]	[246..1]
CMOA_SHELP - Carboxy-S-adenosyl-L-methionine synthase OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=cmoA...	176.0	[0..4]	[246..1]
gi\|27361632, gi\|... - gi\|27365484\|ref\|NP_761012.1\| hypothetical protein VV1_2154 [Vibrio vulnificus CMCP6], gi\|27361632\|gb...	176.0	[0..6]	[246..7]

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Predicted Domain #1

Region A:
Residues: [1-246]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSAMNPKDT LFSAPIDKIG DFTFDERVAE VFPDMIQRSV PGYSNIISAI GMLAERFVKP  60
   61 HSKIYDLGCS LGAATLSMRR HIKQEGCQII AVDNSAAMVE RCKLHLNAYR SDTPVQVIEA 120
  121 DIRDIAIENA SVVVLNFTLQ FLAPDDRYAL LEKIYAGLRP GGILILSEKF VFSDQEAHEL 180
  181 LIDLHHDFKR ANGYSELEIS QKRSAIENVM RPDSIQTHKQ RFATLGFSSF EVWFQCFNFG 240
  241 SMFAIK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.09691
Match:	1im8A
Description:	Hypothetical protein HI0319 (YecO)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.25333584501255	bayes_pls_golite062009
transferase activity	0.999964866871553	bayes_pls_golite062009
methyltransferase activity	0.558878917426836	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.557560946446304	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.0605581837493382	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: