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View Structure Prediction Details

Protein: gi|157170250
Organism: synthetic construct
Length: 544 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|157170250.

Description E-value Query
Range
Subject
Range
PAK3_RAT - Serine/threonine-protein kinase PAK 3 OS=Rattus norvegicus GN=Pak3 PE=1 SV=1
0.0 [1..544] [1..544]
gi|21953248, gi|... - gi|31419805|gb|AAH53403.1| P21 (CDKN1A)-activated kinase 3 [Mus musculus], gi|21953248|emb|CAD42790....
gi|117616564 - gi|117616564|gb|ABK42300.1| Pak3 [synthetic construct]
0.0 [1..544] [1..544]
gi|74008105, gi|... - gi|74008105|ref|XP_549187.2| PREDICTED: similar to Serine/threonine-protein kinase PAK 3 (p21-activa...
0.0 [1..544] [1..544]
gi|55726666 - gi|55726666|emb|CAH90096.1| hypothetical protein [Pongo abelii]
gi|236450231 - gi|236450231|ref|NP_001153267.1| p21-activated kinase 3 [Pongo abelii]
0.0 [1..544] [1..544]
gi|1168176 - gi|1168176|gb|AAB35358.1| mPAK-3=p21Cdc42/Rac activated kinase [mice, fibroblast, Peptide, 543 aa]
0.0 [1..543] [1..543]
PAK3 - p21 (CDKN1A)-activated kinase 3
PAK3_PANTR - Serine/threonine-protein kinase PAK 3 OS=Pan troglodytes GN=PAK3 PE=2 SV=1
PAK3_PONPY - Serine/threonine-protein kinase PAK 3 OS=Pongo pygmaeus GN=PAK3 PE=2 SV=1
0.0 [1..544] [1..559]

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Predicted Domain #1
Region A:
Residues: [1-151]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDGLDNEEK PPAPPLRMNS NNRDSSALNH SSKPLPMAPE EKNKKARLRS IFPGGGDKTN  60
   61 KKKEKERPEI SLPSDFEHTI HVGFDAVTGE FTGIPEQWAR LLQTSNITKL EQKKNPQAVL 120
  121 DVLKFYDSKE TVNNQKYMSF TSGDKSAHGY I

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.82
Match: 1f3mA
Description: pak1 autoregulatory domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [152-247]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAHPSSTKTA SEPPLAPPVS EEEDEEEEEE EDENEPPPVI APRPEHTKSI YTRSVVESIA  60
   61 SPAVPNKEVT PPSAENANSS TLYRNTDRQR KKSKMT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [248-544]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEEILEKLRS IVSVGDPKKK YTRFEKIGQG ASGTVYTALD IATGQEVAIK QMNLQQQPKK  60
   61 ELIINEILVM RENKNPNIVN YLDSYLVGDE LWVVMEYLAG GSLTDVVTET CMDEGQIAAV 120
  121 CRECLQALDF LHSNQVIHRD IKSDNILLGM DGSVKLTDFG FCAQITPEQS KRSTMVGTPY 180
  181 WMAPEVVTRK AYGPKVDIWS LGIMAIEMVE GEPPYLNENP LRALYLIATN GTPELQNPER 240
  241 LSAVFRDFLN RCLEMDVDRR GSAKELLQHP FLKLAKPLSS LTPLIIAAKE AIKNSSR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.09691
Match: 1f3mC
Description: pak1
Matching Structure (courtesy of the PDB):

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