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View Structure Prediction Details

Protein: gi|151942897
Organism: Saccharomyces cerevisiae YJM789
Length: 435 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|151942897.

Description E-value Query
Range
Subject
Range
CGB1_CRILO - (Q08301) G2/mitotic-specific cyclin B1
CCNB1_CRIGR - G2/mitotic-specific cyclin-B1 OS=Cricetulus griseus GN=CCNB1 PE=2 SV=1
0.0 [8..421] [2..417]
gi|254022 - gi|254022|gb|AAB22970.1| cyclin B1 [Mus sp.]
CCNB1_MOUSE - G2/mitotic-specific cyclin-B1 OS=Mus musculus GN=Ccnb1 PE=1 SV=3
0.0 [8..421] [2..418]
CCNB1_MESAU - G2/mitotic-specific cyclin-B1 OS=Mesocricetus auratus GN=CCNB1 PE=2 SV=1
0.0 [8..421] [2..417]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [8..421] [2..418]
CCNB1, CGB1 - chorionic gonadotropin, beta polypeptide 1, cyclin B1
gi|123990181 - gi|123990181|gb|ABM83901.1| cyclin B1 [synthetic construct]
0.0 [8..417] [2..417]
CCNB1_RAT - G2/mitotic-specific cyclin-B1 OS=Rattus norvegicus GN=Ccnb1 PE=2 SV=1
0.0 [8..421] [2..411]
CGS5_YEAST - S-phase entry cyclin-5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CLB5 PE=1 SV=1
gi|151942897 - gi|151942897|gb|EDN61243.1| B-type cyclin [Saccharomyces cerevisiae YJM789]
gi|190408047 - gi|190408047|gb|EDV11312.1| S-phase entry cyclin-5 [Saccharomyces cerevisiae RM11-1a]
CLB5 - B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of ...
0.0 [1..435] [1..435]
gi|147906017, gi... - gi|27735397|gb|AAH41302.1| Ccnb1-prov protein [Xenopus laevis], gi|147906017|ref|NP_001080196.1| cyc...
0.0 [8..419] [2..385]
CCNB2_RANJA - G2/mitotic-specific cyclin-B2 OS=Rana japonica GN=CCNB2 PE=2 SV=1
0.0 [29..421] [2..380]

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Predicted Domain #1
Region A:
Residues: [1-137]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGENHDHEQS IKRNSMIYNE NERQLCNSNL KILQNKRALS KNDSSSKQQV QDSKPRRALT  60
   61 DVPVNNNPLS QNKRIVAGSK AAKVRREENI RPIVSAVQKR QIYNDRTAAE QEEEEEEEGE 120
  121 DDDAASIVNK KRRIDAE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.750 0.022 regulation of cyclin-dependent protein kinase activity a.24.9 alpha-catenin/vinculin
View Download 0.750 0.021 regulation of S phase of mitotic cell cycle a.24.9 alpha-catenin/vinculin
View Download 0.527 0.019 regulation of cyclin-dependent protein kinase activity a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.527 0.017 regulation of S phase of mitotic cell cycle a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.658 0.015 regulation of cyclin-dependent protein kinase activity a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.658 0.015 regulation of S phase of mitotic cell cycle a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.781 0.009 regulation of cyclin-dependent protein kinase activity a.63.1 Apolipophorin-III
View Download 0.781 0.009 regulation of S phase of mitotic cell cycle a.63.1 Apolipophorin-III
View Download 0.702 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.702 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.520 N/A N/A a.26.1 4-helical cytokines
View Download 0.471 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.445 N/A N/A a.118.8 TPR-like
View Download 0.436 N/A N/A a.29.2 Bromodomain
View Download 0.413 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.382 N/A N/A a.62.1 Hepatitis B viral capsid (hbcag)
View Download 0.351 N/A N/A b.82.3 cAMP-binding domain-like
View Download 0.347 N/A N/A e.34.1 NSP3 homodimer
View Download 0.341 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.340 N/A N/A a.26.1 4-helical cytokines
View Download 0.336 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.330 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.329 N/A N/A a.118.8 TPR-like
View Download 0.328 N/A N/A f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.315 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.315 N/A N/A a.47.2 t-snare proteins
View Download 0.313 N/A N/A a.48.2 Transferrin receptor ectodomain, C-terminal domain
View Download 0.310 N/A N/A a.25.1 Ferritin-like
View Download 0.303 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.301 N/A N/A e.37.1 Bifunctional dehydrogenase/ferrochelatase Met8p, dimerisation and C-terminal domains
View Download 0.300 N/A N/A i.11.1 Computational models partly based on NMR data
View Download 0.298 N/A N/A a.25.1 Ferritin-like
View Download 0.297 N/A N/A a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.294 N/A N/A a.1.1 Globin-like
View Download 0.292 N/A N/A d.228.1 Replication modulator SeqA, C-terminal DNA-binding domain
View Download 0.291 N/A N/A a.25.1 Ferritin-like
View Download 0.290 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.277 N/A N/A a.24.11 Bacterial GAP domain
View Download 0.268 N/A N/A a.47.2 t-snare proteins
View Download 0.265 N/A N/A a.7.4 Smac/diablo
View Download 0.260 N/A N/A f.21.1 Transmembrane di-heme cytochromes
View Download 0.259 N/A N/A a.25.1 Ferritin-like
View Download 0.258 N/A N/A c.16.1 Lumazine synthase
View Download 0.256 N/A N/A a.1.1 Globin-like
View Download 0.251 N/A N/A a.24.15 FAD-dependent thiol oxidase
View Download 0.247 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.232 N/A N/A a.24.15 FAD-dependent thiol oxidase
View Download 0.227 N/A N/A a.26.1 4-helical cytokines
View Download 0.227 N/A N/A c.44.2 Enzyme IIB-cellobiose
View Download 0.225 N/A N/A a.7.1 Spectrin repeat
View Download 0.225 N/A N/A a.116.1 GTPase activation domain, GAP
View Download 0.210 N/A N/A c.3.1 FAD/NAD(P)-binding domain
View Download 0.209 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.201 N/A N/A a.7.1 Spectrin repeat

Predicted Domain #2
Region A:
Residues: [138-172]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVSEIVGWQD LDYVEKDDTA MVAEYSAEIF AFLYR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [298-435]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLNFLRRISK ADDYDPVNRN IGKFILEYAY CCHQFIHLPP STVSAMAMYI ARRMTNRNKN  60
   61 ELWNGTLQHY SGGIDPIHDE AFQSLCIDLV KDIASSKTHL DSLILKYKKP RYGSVYFQTF 120
  121 KWCTSEMHSN FQNLFNLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 295.232149
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [173-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RELETLPSHN YLLDKTSKYY LRPSMRTILV DWLVEVHEKF QCYPETLFLS INLMDRFLAK  60
   61 NKVTMNKLQL LAVTSLFIAA KFEEVNLPKL AEYAYITDGA ASKNDIKNAE MFMLTSLEFN 120
  121 IGWPN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 295.232149
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle