YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|227117915, gi...
Organism:	Vibrio cholerae O395
Length:	258 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|227117915, gi....

Description	E-value	Query Range	Subject Range
gi\|223826 - gi\|223826\|prf\|\|1001196A toxin,cholera	388.0	[0..1]	[258..1]
ELAP_ECOLX - Heat-labile enterotoxin A chain OS=Escherichia coli GN=eltA PE=1 SV=1 gi\|148334 - gi\|148334\|gb\|AAA24791.1\| Heat labile toxin subunit A precursor gi\|148338 - gi\|148338\|gb\|AAA24793.1\| Heat-labile toxin subunit A precursor gi\|150459 - gi\|150459\|gb\|AAA98202.1\| heat-labile enterotoxin subunit A	377.0	[0..1]	[258..1]
gi\|88687062 - gi\|88687062\|emb\|CAJ13819.1\| non toxic mutant of heat labile enterotoxin A subunit precursot [Escheri...	376.0	[0..1]	[258..1]
gi\|808899 - gi\|808899\|dbj\|BAA06288.1\| cholera toxin [Vibrio cholerae O37] gi\|254226671, gi... - gi\|254226671\|ref\|ZP_04920249.1\| cholera enterotoxin, A subunit [Vibrio cholerae V51], gi\|225354645\|r... gi\|18448889, gi\|... - gi\|18448891\|gb\|AAL69945.1\| CtxA [Vibrio cholerae], gi\|18448889\|gb\|AAL69944.1\| CtxA [Vibrio cholerae]... gi\|121730328, gi... - gi\|121730328\|ref\|ZP_01682692.1\| cholera enterotoxin, A subunit [Vibrio cholerae V52], gi\|121627920\|g...	375.0	[0..1]	[258..1]
gi\|20502729 - gi\|20502729\|gb\|AAM22586.1\|AF390572_1 cholera toxin A subunit [Vibrio cholerae O27] tr\|Q8L356\|Q8L356... - Cholera toxin A subunit OS=Vibrio cholerae O27 GN=ctxA PE=4 SV=1	373.0	[0..1]	[258..1]
gi\|21667988 - gi\|21667988\|gb\|AAM74170.1\|AF516341_2 CtxA [Vibrio phage CTX]	371.0	[0..1]	[258..1]

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Predicted Domain #1

Region A:
Residues: [1-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKIIFVFFI FLSSFSYAND DKLYRADSRP PDEIKQSGGL MPRGQSEYFD RGTQMNINLY  60
   61 DHARGTQTGF VRHDDGYVST SISLRSAHLV GQTILSGHST YYIYVIATAP NMFNVNDVLG 120
  121 AYSPHPDEQE VSALGGIPYS QIYGWYRVHF GVLDEQLHRN RGYRDRYYSN LDIAPAADGY 180
  181 GLAGFPPEHR AWREEPWIHH APPGCGNAPR SSMSNTCDEK TQSLGVKFLD EYQSKVKRQI 240
  241 FSGYQSDIDT HNRIKDEL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	96.30103
Match:	1s5eA
Description:	Cholera holotoxin, Crystal form 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
NAD+ ADP-ribosyltransferase activity	6.55549320210634	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	4.76528544438237	bayes_pls_golite062009
NAD(P)+-protein-arginine ADP-ribosyltransferase activity	2.30976555175185	bayes_pls_golite062009
transferase activity	1.7229093219327	bayes_pls_golite062009
catalytic activity	1.25705748974699	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.355594977942641	bayes_pls_golite062009
protein binding	0.281759199809355	bayes_pls_golite062009
binding	0.212977268771834	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: