YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|151942618
Organism:	Saccharomyces cerevisiae YJM789
Length:	506 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|151942618.

Description	E-value	Query Range	Subject Range
CG13185-PB - This gene is referred to in FlyBase by the symbol Dmel\CG13185 (CG13185, FBgn0033661). It is a prote...	1.0E-62	[4..490]	[4376..4886]
gi\|190407780 - gi\|190407780\|gb\|EDV11045.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] CTI6_YEAST - Histone deacetylase complex subunit CTI6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN... CTI6 - Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recru... gi\|151942618 - gi\|151942618\|gb\|EDN60964.1\| cyc8-tup1 interacting protein [Saccharomyces cerevisiae YJM789]	2.0E-52	[1..506]	[1..506]
GERIA_BACCE - Spore germination protein GerIA OS=Bacillus cereus GN=gerIA PE=3 SV=1 gi\|229193019, gi... - gi\|229193019\|ref\|ZP_04319975.1\| Spore germination protein gerIA [Bacillus cereus ATCC 10876], gi\|228...	2.0E-44	[195..495]	[8..340]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-43	[2..467]	[22..470]
NFH_MOUSE - (P19246) Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polype...	1.0E-42	[5..483]	[547..1024]
gi\|24020878, gi\|... - gi\|50979202\|ref\|NP_001003352.1\| neurofilament, heavy polypeptide 200kDa [Canis lupus familiaris], gi...	2.0E-41	[2..486]	[487..968]
gi\|30022804, gi\|... - gi\|30022804\|ref\|NP_834435.1\| spore germination protein IA [Bacillus cereus ATCC 14579], gi\|29898363\|... gi\|229130012, gi... - gi\|229130012\|ref\|ZP_04258976.1\| Spore germination protein gerIA [Bacillus cereus BDRD-Cer4], gi\|2286...	4.0E-41	[140..495]	[7..405]
gi\|112044, gi\|26... - gi\|29789026\|ref\|NP_036739.1\| neurofilament, heavy polypeptide [Rattus norvegicus], gi\|2642598\|gb\|AAB...	7.0E-40	[7..473]	[477..936]

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Predicted Domain #1

Region A:
Residues: [1-68]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESTAIVPKG PVVGSEDMEK AEVIASGSTD IISTTSTATT TAAIGSVQEE SVKQEDVPME  60
   61 GGEGEVEE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.281	0.856	positive regulation of transcription	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.281	0.856	positive regulation of transcription	a.71.1	Endoplasmic reticulum protein ERP29, C-domain
View	Download	0.351	0.856	positive regulation of transcription	b.5.1	alpha-Amylase inhibitor tendamistat
View	Download	0.279	0.856	positive regulation of transcription	a.23.5	Hemolysin expression modulating protein HHA
View	Download	0.280	0.856	positive regulation of transcription	d.16.1	FAD-linked reductases, C-terminal domain
View	Download	0.277	0.856	positive regulation of transcription	b.114.1	N-utilization substance G protein NusG, insert domain
View	Download	0.267	0.856	positive regulation of transcription	a.24.10	Histidine-containing phosphotransfer domain, HPT domain
View	Download	0.263	0.856	positive regulation of transcription	b.71.1	Glycosyl hydrolase domain
View	Download	0.220	0.856	positive regulation of transcription	d.58.5	GlnB-like
View	Download	0.217	0.856	positive regulation of transcription	d.49.1	Signal recognition particle alu RNA binding heterodimer, SRP9/14

Predicted Domain #2

Region A:
Residues: [69-127]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EEGETRCICG ELDTPDDSGF FIQCEQCSSW QHGYCVSITQ DNAPDKYWCE QCRPELHQL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	14.455932
Match:	PF00628
Description:	PHD-finger

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [128-506]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTTDTGEARS IYKPVQEKRR QSRRKARSAA ASKSHAANEA EKSPRNTSNT DDNVDDIGDE  60
   61 EDEVEDEASA VALAKDGNTR SSRRRRRNSM DDASTDQYSL DPGDSDKKLL DRKRATFMAR 120
  121 EEKQYQRMLE KALKESRRTS HQEDPESYEN DADIYQGDTD NHNGTTRLQT DVMLTEGKPD 180
  181 SVTNDDMKES LRPSKEQSME KTNDVEKEAS QEKESSTGSA QDTEKTDEPI LPLTSISSSE 240
  241 DDSRKASSRG SKRVSKPARK GNRTRRSNTS SDTNQNRRSA DIGTDKPVKP RLPPQRTSLN 300
  301 EMRRRVSAIL EFISRTQWEL SEDQSDREEF VRFVENQHFV EKVDTIYNGY NESLSMMDDL 360
  361 TRELLLWEKK YSNNTNAIQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [421-506]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQRTSLNEMR RRVSAILEFI SRTQWELSED QSDREEFVRF VENQHFVEKV DTIYNGYNES  60
   61 LSMMDDLTRE LLLWEKKYSN NTNAIQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.899	a.8.3	Families 57/38 glycoside transferase middle domain
View	Download	0.672	a.69.3	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View	Download	0.597	a.112.1	Description not found.
View	Download	0.587	a.7.7	BAG domain
View	Download	0.571	a.47.2	t-snare proteins

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits