YRC Public Data Repository - Protein Structure Prediction

Protein:	GLPX_ECOLI
Organism:	Escherichia coli
Length:	336 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLPX_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|75176688 - gi\|75176688\|ref\|ZP_00696816.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase...	529.0	[0..1]	[336..44]
gi\|56130186, gi\|... - gi\|56415929\|ref\|YP_153004.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica ser... gi\|197364856, gi... - gi\|197364856\|ref\|YP_002144493.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica...	527.0	[0..1]	[336..31]
gi\|29139474, gi\|... - gi\|29143838\|ref\|NP_807180.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica ser... gi\|16762350 - gi\|16762350\|ref\|NP_457967.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica ser... gi\|25302397, gi\|... - gi\|25302397\|pir\|\|AH0939 probable glycerol metabolic protein STY3785 [imported] - Salmonella enterica...	526.0	[0..1]	[336..31]
gi\|224585896, gi... - gi\|224585896\|ref\|YP_002639695.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica... gi\|62182544, gi\|... - gi\|62182544\|ref\|YP_218961.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica ser...	526.0	[0..1]	[336..31]
gi\|206566877, gi... - gi\|206577819\|ref\|YP_002235979.1\| fructose-1,6-bisphosphatase, class II [Klebsiella pneumoniae 342], ... gi\|152972507, gi... - gi\|152972507\|ref\|YP_001337653.1\| fructose 1,6-bisphosphatase II [Klebsiella pneumoniae subsp. pneumo... gi\|893384 - gi\|893384\|dbj\|BAA09535.1\| GlpX [Klebsiella aerogenes] gi\|238897103, gi... - gi\|238897103\|ref\|YP_002921849.1\| fructose 1,6-bisphosphatase II [Klebsiella pneumoniae NTUH-K2044], ...	523.0	[0..1]	[336..1]
gi\|254290626, gi... - gi\|254290626\|ref\|YP_003056374.1\| fructose 1,6-bisphosphatase II [Escherichia coli BL21(DE3)], gi\|253... gi\|83586231, gi\|... - gi\|83586231\|ref\|ZP_00924867.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase... gi\|253975776, gi... - gi\|254163875\|ref\|YP_003046983.1\| fructose 1,6-bisphosphatase II [Escherichia coli B str. REL606], gi... gi\|242379461, gi... - gi\|251787188\|ref\|YP_003001492.1\| hypothetical protein B21_03759 [Escherichia coli BL21], gi\|24237946...	522.0	[0..1]	[336..1]
gi\|254795925, gi... - gi\|254795925\|ref\|YP_003080762.1\| fructose 1,6-bisphosphatase II [Escherichia coli O157:H7 str. TW143... gi\|208812907, gi... - gi\|208812907\|ref\|ZP_03254236.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str.... gi\|208808151, gi... - gi\|208808151\|ref\|ZP_03250488.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str.... gi\|195937567 - gi\|195937567\|ref\|ZP_03082949.1\| fructose 1,6-bisphosphatase II [Escherichia coli O157:H7 str. EC4024... gi\|15834104, gi\|... - gi\|15834104\|ref\|NP_312877.1\| fructose 1,6-bisphosphatase II [Escherichia coli O157:H7 str. Sakai], g... gi\|189378041, gi... - gi\|189378041\|gb\|EDU96457.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC5... gi\|217324329, gi... - gi\|217324329\|ref\|ZP_03440413.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str.... gi\|209160245, gi... - gi\|209398845\|ref\|YP_002273443.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str... gi\|208819391, gi... - gi\|208819391\|ref\|ZP_03259711.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str.... gi\|189367915, gi... - gi\|189367915\|gb\|EDU86331.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4... gi\|189357141, gi... - gi\|189357141\|gb\|EDU75560.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4... gi\|209752310, gi... - pir\|\|B86082 unknown function in glycerol metabolism [imported] - Escherichia coli (strain O157:H7, s... gi\|168748779, gi... - gi\|188016816\|gb\|EDU54938.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4... gi\|15804514, gi\|... - gi\|15804514\|ref\|NP_290554.1\| fructose 1,6-bisphosphatase II [Escherichia coli O157:H7 EDL933], gi\|12... gi\|189373300, gi... - gi\|189373300\|gb\|EDU91716.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC8... gi\|15834104, gi\|... - gi\|15834104\|ref\|NP_312877.1\| fructose 1,6-bisphosphatase II [Escherichia coli O157:H7], gi\|13364326\|... gi\|189001541, gi... - gi\|189001541\|gb\|EDU70527.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4... gi\|187769214, gi... - gi\|187769214\|gb\|EDU33058.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4... gi\|189362660, gi... - gi\|189362660\|gb\|EDU81079.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4...	522.0	[0..1]	[336..1]
gi\|34811420 - gi\|34811420\|pdb\|1NI9\|A Chain A, 2.0 A Structure Of Glycerol Metabolism Protein From E. Coli	522.0	[0..1]	[336..3]
gi\|75230446, gi\|... - gi\|75230446\|ref\|ZP_00716932.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase...	521.0	[0..1]	[336..1]
gi\|115515316, gi... - gi\|117626192\|ref\|YP_859515.1\| fructose 1,6-bisphosphatase II [Escherichia coli APEC O1], gi\|11551531...	520.0	[0..1]	[336..1]

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Predicted Domain #1

Region A:
Residues: [1-336]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRELAIEFS RVTESAALAG YKWLGRGDKN TADGAAVNAM RIMLNQVNID GTIVIGEGEI  60
   61 DEAPMLYIGE KVGTGRGDAV DIAVDPIEGT RMTAMGQANA LAVLAVGDKG CFLNAPDMYM 120
  121 EKLIVGPGAK GTIDLNLPLA DNLRNVAAAL GKPLSELTVT ILAKPRHDAV IAEMQQLGVR 180
  181 VFAIPDGDVA ASILTCMPDS EVDVLYGIGG APEGVVSAAV IRALDGDMNG RLLARHDVKG 240
  241 DNEENRRIGE QELARCKAMG IEAGKVLRLG DMARSDNVIF SATGITKGDL LEGISRKGNI 300
  301 ATTETLLIRG KSRTIRRIQS IHYLDRKDPE MQVHIL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	149.0
Match:	1ni9A
Description:	Glycerol metabolism protein GlpX
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
fructose 1,6-bisphosphate 1-phosphatase activity	3.7882342162091	bayes_pls_golite062009
catalytic activity	2.50273222033908	bayes_pls_golite062009
carbohydrate phosphatase activity	1.71805011594822	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.12147750685256	bayes_pls_golite062009
phosphatase activity	1.0818856732251	bayes_pls_golite062009
phosphoric ester hydrolase activity	1.05563946024763	bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity	0.807607481385419	bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity	0.61593402109125	bayes_pls_golite062009
inositol-1(or 4)-monophosphatase activity	0.224541466803371	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: