YRC Public Data Repository - Protein Structure Prediction

Protein:	GLND_ECOLI
Organism:	Escherichia coli
Length:	890 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLND_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|124499765, gi... - gi\|124529609\|ref\|ZP_01700553.1\| UTP-GlnB uridylyltransferase, GlnD [Escherichia coli B], gi\|12449976... gi\|251783726, gi... - gi\|251783726\|ref\|YP_002998030.1\| hypothetical protein B21_00164 [Escherichia coli BL21], gi\|24237599... gi\|83585483, gi\|... - gi\|83585483\|ref\|ZP_00924128.1\| COG2844: UTP:GlnB (protein PII) uridylyltransferase [Escherichia coli... gi\|253972187, gi... - gi\|254160286\|ref\|YP_003043394.1\| PII uridylyl-transferase [Escherichia coli B str. REL606], gi\|25397... gi\|253976396, gi... - gi\|254287089\|ref\|YP_003052837.1\| PII uridylyl-transferase [Escherichia coli BL21(DE3)], gi\|253976396... GLND_ECOLC - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Escherichia coli (strain ATCC 8739 / DS...	795.0	[0..1]	[890..1]
GLND_SHIB3 - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Shigella boydii serotype 18 (strain CDC...	794.0	[0..1]	[890..1]
GLND_ECOHS - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Escherichia coli O9:H4 (strain HS) GN=g... gi\|75258844, gi\|... - gi\|75258844\|ref\|ZP_00730234.1\| COG2844: UTP:GlnB (protein PII) uridylyltransferase [Escherichia coli... GLND_ECO8A - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Escherichia coli O8 (strain IAI1) GN=gl... GLND_SHIBS - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Shigella boydii serotype 4 (strain Sb22... GLND_ECO55 - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Escherichia coli (strain 55989 / EAEC) ... gi\|194413644, gi... - gi\|75210490\|ref\|ZP_00710641.1\| COG2844: UTP:GlnB (protein PII) uridylyltransferase [Escherichia coli... gi\|75230472, gi\|... - gi\|75230472\|ref\|ZP_00716953.1\| COG2844: UTP:GlnB (protein PII) uridylyltransferase [Escherichia coli... GLND_ECOSE - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Escherichia coli (strain SE11) GN=glnD ...	794.0	[0..1]	[890..1]
GLND_SHISS - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Shigella sonnei (strain Ss046) GN=glnD ...	794.0	[0..1]	[890..1]
GLND_ECO57 - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Escherichia coli O157:H7 GN=glnD PE=3 S... gi\|217325875, gi... - gi\|217325875\|ref\|ZP_03441959.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. TW14... GLND_ECO5E - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Escherichia coli O157:H7 (strain EC4115... gi\|208807602, gi... - gi\|208807602\|ref\|ZP_03249939.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC42... gi\|195938152 - gi\|195938152\|ref\|ZP_03083534.1\| PII uridylyl-transferase [Escherichia coli O157:H7 str. EC4024] gi\|15799849, gi\|... - gi\|15799849\|ref\|NP_285861.1\| PII uridylyl-transferase [Escherichia coli O157:H7 EDL933], gi\|12512889... gi\|208739221, gi... - gi\|208819098\|ref\|ZP_03259418.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC40... gi\|209745878, gi... - pir\|\|A85501 protein PII-uridylyltransferase [imported] - Escherichia coli (strain O157:H7, substrain... gi\|208814167, gi... - gi\|208814167\|ref\|ZP_03255496.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC40... gi\|189000436, gi... - gi\|189000436\|gb\|EDU69422.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC4076],... gi\|187767697, gi... - gi\|187767697\|gb\|EDU31541.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC4196],... gi\|189375685, gi... - gi\|189375685\|gb\|EDU94101.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC508], ... gi\|168789275, gi... - gi\|189371115\|gb\|EDU89531.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC869], ... gi\|189357031, gi... - gi\|189357031\|gb\|EDU75450.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC4401],... gi\|188014575, gi... - gi\|188014575\|gb\|EDU52697.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC4113],... gi\|168770361, gi... - gi\|189360712\|gb\|EDU79131.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC4486],... gi\|168764327, gi... - gi\|189365647\|gb\|EDU84063.1\| protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC4501],... gi\|15829423, gi\|... - gi\|15829423\|ref\|NP_308196.1\| PII uridylyl-transferase [Escherichia coli O157:H7 str. Sakai], gi\|1335... gi\|254791300, gi... - gi\|254791300\|ref\|YP_003076137.1\| uridylyltransferase/uridylyl-removing enzyme [Escherichia coli O157...	794.0	[0..1]	[890..1]
GLND_SHIDS - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Shigella dysenteriae serotype 1 (strain...	794.0	[0..1]	[890..1]
gi\|193067726, gi... - gi\|75238870\|ref\|ZP_00722852.1\| COG2844: UTP:GlnB (protein PII) uridylyltransferase [Escherichia coli...	794.0	[0..1]	[890..1]
gi\|83569749, gi\|... - gi\|83569749\|ref\|ZP_00921199.1\| COG2844: UTP:GlnB (protein PII) uridylyltransferase [Shigella dysente...	793.0	[0..1]	[890..1]
gi\|226840692, gi... - gi\|254037586\|ref\|ZP_04871663.1\| uridylyltransferase [Escherichia sp. 1_1_43], gi\|226840692\|gb\|EEH726... gi\|188488183, gi... - gi\|75512179\|ref\|ZP_00734751.1\| COG2844: UTP:GlnB (protein PII) uridylyltransferase [Escherichia coli...	793.0	[0..1]	[890..1]
GLND_ECOK1 - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Escherichia coli O1:K1 / APEC GN=glnD P... GLND_ECOUT - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Escherichia coli (strain UTI89 / UPEC) ... GLND_ECO45 - Bifunctional uridylyltransferase/uridylyl-removing enzyme OS=Escherichia coli O45:K1 (strain S88 / E... gi\|237704326, gi... - gi\|237704326\|ref\|ZP_04534807.1\| uridylyltransferase [Escherichia sp. 3_2_53FAA], gi\|226902238\|gb\|EEH...	793.0	[0..1]	[890..1]

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Predicted Domain #1

Region A:
Residues: [1-213]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTLPEQYAN TALPTLPGQP QNPCVWPRDE LTVGGIKAHI DTFQRWLGDA FDNGISAEQL  60
   61 IEARTEFIDQ LLQRLWIEAG FSQIADLALV AVGGYGRGEL HPLSDVDLLI LSRKKLPDDQ 120
  121 AQKVGELLTL LWDVKLEVGH SVRTLEECML EGLSDLTVAT NLIESRLLIG DVALFLELQK 180
  181 HIFSEGFWPS DKFYAAKVEE QNQRHQRYHG TSY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1v4aA
Description:	Structure of the N-terminal Domain of Escherichia coli Glutamine Synthetase adenylyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring phosphorus-containing groups	2.41308867449214	bayes_pls_golite062009
[glutamate-ammonia-ligase] adenylyltransferase activity	1.82264747359149	bayes_pls_golite062009
transferase activity	1.78252455260241	bayes_pls_golite062009
catalytic activity	1.122769147009	bayes_pls_golite062009
nucleotidyltransferase activity	0.78517703623017	bayes_pls_golite062009
binding	0.712563149474185	bayes_pls_golite062009
nucleic acid binding	0.0435534014305499	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [214-568]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLEPDIKSSP GGLRDIHTLQ WVARRHFGAT SLDEMVGFGF LTSAERAELN ECLHILWRIR  60
   61 FALHLVVSRY DNRLLFDRQL SVAQRLNYSG EGNEPVERMM KDYFRVTRRV SELNQMLLQL 120
  121 FDEAILALPA DEKPRPIDDE FQLRGTLIDL RDETLFMRQP EAILRMFYTM VHNSAITGIY 180
  181 STTLRQLRHA RRHLQQPLCN IPEARKLFLS ILRHPGAVRR GLLPMHRHSV LGAYMPQWSH 240
  241 IVGQMQFDLF HAYTVDEHTI RVMLKLESFA SEETRQRHPL CVDVWPRLPS TELIFIAALF 300
  301 HDIAKGRGGD HSILGAQDVV HFAELHGLNS RETQLVAWLV RQHLLMSVTA QRRDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.0
Match:	1mivA
Description:	tRNA CCA-adding enzyme, C-terminal domains; tRNA CCA-adding enzyme, head domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring phosphorus-containing groups	2.41308867449214	bayes_pls_golite062009
[glutamate-ammonia-ligase] adenylyltransferase activity	1.82264747359149	bayes_pls_golite062009
transferase activity	1.78252455260241	bayes_pls_golite062009
catalytic activity	1.122769147009	bayes_pls_golite062009
nucleotidyltransferase activity	0.78517703623017	bayes_pls_golite062009
binding	0.712563149474185	bayes_pls_golite062009
nucleic acid binding	0.0435534014305499	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [569-694]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDPEVIKQFA EEVQTENRLR YLVCLTVADI CATNETLWNS WKQSLLRELY FATEKQLRRG  60
   61 MQNTPDMRER VRHHQLQALA LLRMDNIDEE ALHQIWSRCR ANYFVRHSPN QLAWHARHLL 120
  121 QHDLSK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.871	0.006	amino acid binding	f.36.1	Neurotransmitter-gated ion-channel pransmembrane pore

Predicted Domain #4

Region A:
Residues: [695-890]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLVLLSPQAT RGGTEIFIWS PDRPYLFAAV CAELDRRNLS VHDAQIFTTR DGMAMDTFIV  60
   61 LEPDGNPLSA DRHEVIRFGL EQVLTQSSWQ PPQPRRQPAK LRHFTVETEV TFLPTHTDRK 120
  121 SFLELIALDQ PGLLARVGKI FADLGISLHG ARITTIGERV EDLFIIATAD RRALNNELQQ 180
  181 EVHQRLTEAL NPNDKG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.0
Match:	2nyiA
Description:	No description for 2nyiA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: