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View Structure Prediction Details

Protein: GLHA_SHEEP
Organism: Ovis aries
Length: 120 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLHA_SHEEP.

Description E-value Query
Range		 Subject
Range
GLHA_PIG - Glycoprotein hormones alpha chain OS=Sus scrofa GN=CGA PE=1 SV=2
gi|226399, gi|10... - gi|226399|prf||1510300A glycoprotein hormone alpha, pir||UTPGA glycoprotein hormones alpha chain pre...
 223.0 [0..1] [120..1]
GLHA_PANTA - Glycoprotein hormones alpha chain OS=Panthera tigris altaica GN=CGA PE=2 SV=1
 223.0 [0..1] [120..1]
GLHA_BOSMU - Glycoprotein hormones alpha chain OS=Bos mutus grunniens GN=CGA PE=3 SV=1
GLHA_BOVIN - Glycoprotein hormones alpha chain OS=Bos taurus GN=CGA PE=1 SV=1
 223.0 [0..1] [120..1]
GLHA_AILFU - Glycoprotein hormones alpha chain OS=Ailurus fulgens GN=CGA PE=2 SV=1
 223.0 [0..1] [120..1]
gi|88595363 - gi|88595363|dbj|BAE79777.1| glycoprotein hormones, alpha subunit precursor protein [Phodopus sungoru...
 223.0 [0..1] [120..2]
GLHA_TRIVU - Glycoprotein hormones alpha chain OS=Trichosurus vulpecula GN=CGA PE=2 SV=1
GLHA_MONDO - Glycoprotein hormones alpha chain OS=Monodelphis domestica GN=CGA PE=2 SV=1
GLHA_MACRU - Glycoprotein hormones alpha chain OS=Macropus rufus GN=CGA PE=2 SV=1
 223.0 [0..1] [120..1]
GLHA_CERNI - Glycoprotein hormones alpha chain OS=Cervus nippon GN=CGA PE=2 SV=1
 223.0 [0..1] [120..1]
GLHA_BUBBU - Glycoprotein hormones alpha chain OS=Bubalus bubalis GN=CGA PE=2 SV=1
 222.0 [0..1] [120..1]
GLHA_FELCA - Glycoprotein hormones alpha chain OS=Felis catus GN=CGA PE=2 SV=1
 222.0 [0..1] [119..1]
gi|3719213 - gi|3719213|gb|AAC63900.1| gonadotrophin alpha subunit [Trichosurus vulpecula]
 222.0 [0..1] [120..1]

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Predicted Domain #1
Region A:
Residues: [1-120] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYYRKYAAA ILAILSLFLQ ILHSFPDGEF TMQGCPECKL KENKYFSKPD APIYQCMGCC  60
   61 FSRAYPTPAR SKKTMLVPKN ITSEATCCVA KAFTKATVMG NVRVENHTEC HCSTCYYHKS 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.30103
Match: 1dz7A
Description: Glycoprotein hormones alpha chain (Gonadotropin A, Follitropin alpha)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.64101807129423 bayes_pls_golite062009
protein binding 2.36794464190805 bayes_pls_golite062009
receptor binding 2.06356245258405 bayes_pls_golite062009
protein dimerization activity 1.3520160311608 bayes_pls_golite062009
protein homodimerization activity 1.15151644642973 bayes_pls_golite062009
identical protein binding 0.978750544050781 bayes_pls_golite062009
growth factor activity 0.522610984957055 bayes_pls_golite062009
catalytic activity 0.105223830172599 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle