YRC Public Data Repository - Protein Structure Prediction

Protein:	ISPH_YERPP
Organism:	Yersinia pestis Pestoides F
Length:	317 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ISPH_YERPP.

Description	E-value	Query Range	Subject Range
gi\|22127571, gi\|... - gi\|22127571\|ref\|NP_670994.1\| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Yersinia pestis KIM... gi\|45443434, gi\|... - gi\|45443434\|ref\|NP_994973.1\| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Yersinia pestis bio...	0.0	[1..317]	[9..325]
gi\|77961930 - gi\|77961930\|ref\|ZP_00825758.1\| COG0761: Penicillin tolerance protein [Yersinia mollaretii ATCC 43969...	0.0	[1..317]	[1..317]
gi\|77976148 - gi\|77976148\|ref\|ZP_00831681.1\| COG0761: Penicillin tolerance protein [Yersinia frederiksenii ATCC 33...	0.0	[1..317]	[1..317]
gi\|77959747 - gi\|77959747\|ref\|ZP_00823764.1\| COG0761: Penicillin tolerance protein [Yersinia bercovieri ATCC 43970...	0.0	[1..317]	[1..317]
ISPH_YERPS - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Yersinia pseudotuberculosis serotype I (strain... ISPH_YERPS - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Yersinia pseudotuberculosis GN=ispH PE=3 SV=1 ISPH_YERPB - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Yersinia pseudotuberculosis serotype IB (strai... ISPH_YERPY - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Yersinia pseudotuberculosis serotype O:3 (stra...	0.0	[1..317]	[1..317]
ISPH_YERP3 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Yersinia pseudotuberculosis serotype O:1b (str...	0.0	[1..317]	[1..317]
gi\|77976918 - gi\|77976918\|ref\|ZP_00832383.1\| COG0761: Penicillin tolerance protein [Yersinia intermedia ATCC 29909...	0.0	[1..317]	[1..317]
ISPH_PHOLL - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Photorhabdus luminescens subsp. laumondii GN=i... ISPH_PHOLL - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Photorhabdus luminescens subsp. laumondii (str...	0.0	[1..316]	[1..316]
ISPH_PSEE4 - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pseudomonas entomophila (strain L48) GN=ispH P... gi\|95112630 - gi\|95112630\|emb\|CAK17358.1\| hydroxymethylbutenyl pyrophosphate reductase [Pseudomonas entomophila L4...	0.0	[1..312]	[1..312]
ISPH_ERWCT - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Erwinia carotovora subsp. atroseptica GN=ispH ... ISPH_PECAS - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase OS=Pectobacterium atrosepticum (strain SCRI 1043 ...	0.0	[1..317]	[1..316]

Back

Predicted Domain #1

Region A:
Residues: [1-76]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQILLANPRG FCAGVDRAIS IVERAIEMYG APIYVRHEVV HNRYVVESLC ERGAIFIEEI  60
   61 SEVPDGSILI FSAHGV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [77-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQAVRAEARS RNLTMLFDAT CPLVTKVHME VARASRKGKE AILIGHAGHP EVEGTMGQYS  60
   61 NPNGGMYLVE SPDDVWQLNV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [157-317]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDENNLCFMT QTTLSVDDTS AVIDALNTRF PKIVGPRKDD ICYATTNRQE AVRNLANDAD  60
   61 IVLVVGSKNS SNSNRLAELV QRMGKPAYLI DSAADIQEFW LQGAKCIGVT AGASAPDILV 120
  121 QQVIARLKDL GAGESIELSG REENIVFEVP KELRVEVKQI D

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.933	0.917	terpenoid biosynthetic process	c.2.1	NAD(P)-binding Rossmann-fold domains

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits