YRC Public Data Repository - Protein Structure Prediction

Protein:	GADW_ECOLI
Organism:	Escherichia coli
Length:	242 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GADW_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|114550315, gi... - gi\|114769398\|ref\|ZP_01447024.1\| transcriptional regulator, AraC family protein [alpha proteobacteriu... gi\|114769398 - gi\|114769398\|ref\|ZP_01447024.1\| transcriptional regulator, AraC family protein [alpha proteobacteriu...	170.0	[0..13]	[236..98]
gi\|85824568, gi\|... - gi\|86138921\|ref\|ZP_01057493.1\| transcriptional regulator, AraC family protein [Roseobacter sp. MED19...	169.0	[0..16]	[242..86]
gi\|46192182, gi\|... - gi\|77463480\|ref\|YP_352984.1\| transcriptional regulator [Rhodobacter sphaeroides 2.4.1], gi\|77387898\|... gi\|83363728, gi\|... - gi\|83374927\|ref\|ZP_00919693.1\| Helix-turn-helix, AraC type [Rhodobacter sphaeroides ATCC 17029], gi\|... gi\|221639339, gi... - gi\|221639339\|ref\|YP_002525601.1\| Transcriptional regulator, AraC family with amidase-like domain [Rh...	169.0	[0..16]	[241..115]
gi\|85703105, gi\|... - gi\|85703105\|ref\|ZP_01034209.1\| transcriptional regulator, AraC family protein [Roseovarius sp. 217],...	169.0	[0..25]	[242..119]
gi\|68233379, gi\|... - gi\|68233379\|ref\|ZP_00572501.1\| Helix-turn-helix, AraC type:ThiJ/PfpI [Frankia sp. EAN1pec], gi\|68198...	169.0	[0..19]	[242..120]
gi\|29605013, gi\|... - gi\|29827912\|ref\|NP_822546.1\| AraC family transcription regulator [Streptomyces avermitilis MA-4680],...	167.0	[0..20]	[238..125]
gi\|119386640, gi... - gi\|69933326\|ref\|ZP_00628528.1\| Helix-turn-helix, AraC type:ThiJ/PfpI [Paracoccus denitrificans PD122...	167.0	[0..15]	[239..116]
gi\|109455977, gi... - gi\|110679861\|ref\|YP_682868.1\| AraC family transcriptional regulator [Roseobacter denitrificans OCh 1...	167.0	[0..25]	[242..100]
gi\|56696814, gi\|... - gi\|56696814\|ref\|YP_167176.1\| AraC family transcriptional regulator [Ruegeria pomeroyi DSS-3], gi\|566...	166.0	[0..25]	[240..111]
gi\|84391182, gi\|... - gi\|84501115\|ref\|ZP_00999350.1\| transcriptional regulator, AraC family protein [Oceanicola batsensis ...	166.0	[0..21]	[242..106]

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Predicted Domain #1

Region A:
Residues: [1-60]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTHVCSVILI RRSFDIYHEQ QKISLHNESI LLLEKNLADD FAFCSPDTRR LDIDELTVCH  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.522879
Match:	1xjaA
Description:	Apo form of the Y31V mutant dimerization domain fragment of Escherichia coli regulatory protein AraC
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [61-242]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YLQNIRQLPR NLGLHSKDRL LINQSPPMPL VTAIFDSFNE SGVNSPILSN MLYLSCLSMF  60
   61 SHKKELIPLL FNSISTVSGK VERLISFDIA KRWYLRDIAE RMYTSESLIK KKLQDENTCF 120
  121 SKILLASRMS MARRLLELRQ IPLHTIAEKC GYSSTSYFIN TFRQYYGVTP HQFAQHSPGT 180
  181 FS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.0
Match:	1wpkA
Description:	Methylated Form of N-terminal Transcriptional Regulator Domain of Escherichia Coli Ada Protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits