YRC Public Data Repository - Protein Structure Prediction

Protein:	FUCK_ECOLI
Organism:	Escherichia coli
Length:	482 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUCK_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|7434247 - gi\|7434247\|pir\|\|C72254 glycerol kinase - Thermotoga maritima (strain MSB8) gi\|15644181, gi\|... - gi\|4981995\|gb\|AAD36500.1\|AE001795_3 glycerol kinase [Thermotoga maritima MSB8], gi\|15644181\|ref\|NP_2...	472.0	[0..13]	[482..1]
GLPK2_THEMA, GLK... - Glycerol kinase 2 OS=Thermotoga maritima GN=glpK2 PE=3 SV=2, (Q9X1E4) Glycerol kinase 2 (EC 2.7.1.30... GLPK2_THEMA - Glycerol kinase 2 OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=glpK2 ...	472.0	[0..13]	[482..1]
GLPK_CARHZ - Glycerol kinase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) GN=gl...	462.0	[0..11]	[482..1]
gi\|254479176, gi... - gi\|254479176\|ref\|ZP_05092524.1\| glycerol kinase [Carboxydibrachium pacificum DSM 12653], gi\|22348899... GLPK_CALS4 - Glycerol kinase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 ... GLPK_THETN - Glycerol kinase OS=Thermoanaerobacter tengcongensis GN=glpK PE=3 SV=1	461.0	[0..14]	[482..3]
gi\|242257967, gi... - gi\|242257967\|ref\|ZP_04802809.1\| glycerol kinase [Thermoanaerobacter sp. X513], gi\|242230500\|gb\|EES32... GLPK_THEPX - Glycerol kinase OS=Thermoanaerobacter sp. (strain X514) GN=glpK PE=3 SV=1	457.0	[0..14]	[482..3]
GLPK_PYRAB - Glycerol kinase OS=Pyrococcus abyssi GN=glpK PE=3 SV=1 GLPK_PYRAB - Glycerol kinase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=glpK PE=3 SV=1	455.0	[0..9]	[482..1]
GLPK_STAEP - (Q8CSS0) Glycerol kinase (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK) GLPK_STAEQ - Glycerol kinase OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) GN=glpK PE=3 SV=1 GLPK_STAES - Glycerol kinase OS=Staphylococcus epidermidis (strain ATCC 12228) GN=glpK PE=3 SV=1 gi\|251805891, gi... - gi\|251810731\|ref\|ZP_04825204.1\| glycerol kinase [Staphylococcus epidermidis BCM-HMP0060], gi\|2518058...	452.0	[0..13]	[482..2]
GLPK_THEP3 - Glycerol kinase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) GN=glpK PE=3 SV=1 gi\|241903306, gi... - gi\|241903306\|ref\|ZP_04788032.1\| glycerol kinase [Thermoanaerobacter brockii subsp. finnii Ako-1], gi...	452.0	[0..14]	[482..3]
gi\|224499801 - gi\|224499801\|ref\|ZP_03668150.1\| glycerol kinase [Listeria monocytogenes Finland 1988] GLPK_LISMO - Glycerol kinase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=glpK PE=3 SV... GLPK_LISMO - Glycerol kinase OS=Listeria monocytogenes GN=glpK PE=3 SV=1 gi\|224501522 - gi\|224501522\|ref\|ZP_03669829.1\| glycerol kinase [Listeria monocytogenes FSL R2-561] gi\|153174697, gi... - gi\|254828228\|ref\|ZP_05232915.1\| glycerol kinase [Listeria monocytogenes FSL N3-165], gi\|153174697\|re... gi\|254829703, gi... - gi\|254829703\|ref\|ZP_05234358.1\| glycerol kinase [Listeria monocytogenes 10403S], gi\|153196827\|ref\|ZP...	451.0	[0..11]	[482..1]
GLPK_BACAH - Glycerol kinase OS=Bacillus thuringiensis (strain Al Hakam) GN=glpK PE=3 SV=1 gi\|229183337, gi... - gi\|229183337\|ref\|ZP_04310565.1\| Glycerol kinase [Bacillus cereus BGSC 6E1], gi\|228600121\|gb\|EEK57713... gi\|196024832, gi... - gi\|196044193\|ref\|ZP_03111429.1\| glycerol kinase [Bacillus cereus 03BB108], gi\|196024832\|gb\|EDX63503.... GLPK_BACC3 - Glycerol kinase OS=Bacillus cereus (strain 03BB102) GN=glpK PE=3 SV=1 GLPK_BACCZ - Glycerol kinase OS=Bacillus cereus (strain ZK / E33L) GN=glpK PE=3 SV=1	451.0	[0..13]	[482..2]

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Predicted Domain #1

Region A:
Residues: [1-482]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSGYIAGAI MKQEVILVLD CGATNVRAIA VNRQGKIVAR ASTPNASDIA MENNTWHQWS  60
   61 LDAILQRFAD CCRQINSELT ECHIRGIAVT TFGVDGALVD KQGNLLYPII SWKCPRTAAV 120
  121 MDNIERLISA QRLQAISGVG AFSFNTLYKL VWLKENHPQL LERAHAWLFI SSLINHRLTG 180
  181 EFTTDITMAG TSQMLDIQQR DFSPQILQAT GIPRRLFPRL VEAGEQIGTL QNSAAAMLGL 240
  241 PVGIPVISAG HDTQFALFGA GAEQNEPVLS SGTWEILMVR SAQVDTSLLS QYAGSTCELD 300
  301 SQAGLYNPGM QWLASGVLEW VRKLFWTAET PWQMLIEEAR LIAPGADGVK MQCDLLSCQN 360
  361 AGWQGVTLNT TRGHFYRAAL EGLTAQLQRN LQMLEKIGHF KASELLLVGG GSRNTLWNQI 420
  421 KANMLDIPVK VLDDAETTVA GAALFGWYGV GEFNSPEEAR AQIHYQYRYF YPQTEPEFIE 480
  481 EV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	123.0
Match:	2p3rA
Description:	No description for 2p3rA was found.

Predicted functions:

Term	Confidence	Notes
glycerol kinase activity	3.01012083918601	bayes_pls_golite062009
carbohydrate kinase activity	0.7849166795124	bayes_pls_golite062009
catalytic activity	0.666924658593345	bayes_pls_golite062009
binding	0.580452706364769	bayes_pls_golite062009
hexokinase activity	0.32024736915472	bayes_pls_golite062009
protein binding	0.138360174861843	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: