YRC Public Data Repository - Protein Structure Prediction

Protein:	FTSA_ECOLI
Organism:	Escherichia coli
Length:	420 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FTSA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|90326058, gi\|... - gi\|90413043\|ref\|ZP_01221041.1\| putative cell division protein FtsA [Photobacterium profundum 3TCK], ...	357.0	[0..1]	[420..1]
gi\|54310300, gi\|... - gi\|54310300\|ref\|YP_131320.1\| cell division protein FtsA [Photobacterium profundum SS9], gi\|46914741\|...	356.0	[0..1]	[420..1]
gi\|114321337, gi... - gi\|78701777\|ref\|ZP_00866224.1\| Cell division protein FtsA [Alkalilimnicola ehrlichei MLHE-1], gi\|785...	355.0	[0..1]	[420..1]
gi\|88701931, gi\|... - gi\|88704104\|ref\|ZP_01101819.1\| Cell division protein FtsA [gamma proteobacterium KT 71], gi\|88701931...	354.0	[0..1]	[420..1]
gi\|53757202, gi\|... - gi\|53803441\|ref\|YP_114838.1\| cell division protein FtsA [Methylococcus capsulatus str. Bath], gi\|537...	354.0	[0..1]	[420..1]
gi\|83648518, gi\|... - gi\|83648518\|ref\|YP_436953.1\| cell division protein FtsA [Hahella chejuensis KCTC 2396], gi\|83636561\|...	352.0	[0..2]	[420..1]
FTSA_SHIFL - Cell division protein FtsA OS=Shigella flexneri GN=ftsA PE=3 SV=1	350.0	[0..1]	[420..1]
gi\|226943457, gi... - gi\|67156140\|ref\|ZP_00417766.1\| Cell division protein FtsA [Azotobacter vinelandii AvOP], gi\|67086470... gi\|23103646, gi\|... - gi\|67156140\|ref\|ZP_00417766.1\| Cell division protein FtsA [Azotobacter vinelandii AvOP], ref\|ZP_0009...	350.0	[0..1]	[420..1]
gi\|36786949, gi\|... - gi\|37527514\|ref\|NP_930858.1\| cell division protein FtsA [Photorhabdus luminescens subsp. laumondii T...	349.0	[0..1]	[420..1]
gi\|117924058, gi... - gi\|69256637\|ref\|ZP_00606131.1\| Cell division protein FtsA [Magnetococcus sp. MC-1], gi\|68247429\|gb\|E...	349.0	[0..2]	[420..1]

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Predicted Domain #1

Region A:
Residues: [1-420]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKATDRKLV VGLEIGTAKV AALVGEVLPD GMVNIIGVGS CPSRGMDKGG VNDLESVVKC  60
   61 VQRAIDQAEL MADCQISSVY LALSGKHISC QNEIGMVPIS EEEVTQEDVE NVVHTAKSVR 120
  121 VRDEHRVLHV IPQEYAIDYQ EGIKNPVGLS GVRMQAKVHL ITCHNDMAKN IVKAVERCGL 180
  181 KVDQLIFAGL ASSYSVLTED ERELGVCVVD IGGGTMDIAV YTGGALRHTK VIPYAGNVVT 240
  241 SDIAYAFGTP PSDAEAIKVR HGCALGSIVG KDESVEVPSV GGRPPRSLQR QTLAEVIEPR 300
  301 YTELLNLVNE EILQLQEKLR QQGVKHHLAA GIVLTGGAAQ IEGLAACAQR VFHTQVRIGA 360
  361 PLNITGLTDY AQEPYYSTAV GLLHYGKESH LNGEAEVEKR VTASVGSWIK RLNSWLRKEF 420
  421

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	89.0
Match:	1yuwA
Description:	crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.124320622497806	bayes_pls_golite062009
protein binding	0.024371510339825	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: