YRC Public Data Repository - Protein Structure Prediction

Protein:	FRUR_ECOLI
Organism:	Escherichia coli
Length:	334 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FRUR_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|167038831, gi... - gi\|167038831\|ref\|YP_001661816.1\| periplasmic binding protein/LacI transcriptional regulator [Thermoa... gi\|242258204, gi... - gi\|242258204\|ref\|ZP_04803030.1\| transcriptional regulator, LacI family [Thermoanaerobacter sp. X513]...	371.0	[0..1]	[332..3]
gi\|20515183, gi\|... - gi\|20806727\|ref\|NP_621898.1\| transcriptional regulator [Thermoanaerobacter tengcongensis MB4], gi\|20... gi\|20806727 - gi\|20806727\|ref\|NP_621898.1\| Transcriptional regulator [Thermoanaerobacter tengcongensis MB4] gi\|254478068, gi... - gi\|254478068\|ref\|ZP_05091451.1\| Periplasmic binding proteins and sugar binding domain of the LacI fa...	371.0	[0..1]	[332..3]
gi\|76797419, gi\|... - gi\|76797419\|ref\|ZP_00779738.1\| regulatory protein, LacI:Periplasmic binding protein/LacI transcripti... gi\|241882990, gi... - gi\|241904637\|ref\|ZP_04789316.1\| transcriptional regulator, LacI family [Thermoanaerobacter brockii s...	360.0	[0..1]	[332..3]
gi\|89209818, gi\|... - gi\|89209818\|ref\|ZP_01188212.1\| regulatory protein, LacI:Periplasmic binding protein/LacI transcripti...	355.0	[0..1]	[332..3]
gi\|51891908, gi\|... - gi\|51891908\|ref\|YP_074599.1\| LacI family transcriptional repressor [Symbiobacterium thermophilum IAM...	347.0	[0..1]	[333..1]
gi\|90410173, gi\|... - gi\|90410173\|ref\|ZP_01218190.1\| Putative ribose operon repressor, rbsR [Photobacterium profundum 3TCK...	343.0	[0..2]	[333..3]
gi\|90439667, gi\|... - gi\|90578834\|ref\|ZP_01234644.1\| putative transcriptional regulator, LacI family protein [Vibrio angus...	343.0	[0..2]	[332..3]

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Predicted Domain #1

Region A:
Residues: [1-61]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLDEIARLA GVSRTTASYV INGKAKQYRV SDKTVEKVMA VVREHNYHPN AVAAGLRAGR  60
   61 T

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.78
Match:	1uxcA
Description:	FRUCTOSE REPRESSOR DNA-BINDING DOMAIN, NMR, MINIMIZED STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleic acid binding	3.44439916460087	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [62-334]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSIGLVIPDL ENTSYTRIAN YLERQARQRG YQLLIACSED QPDNEMRCIE HLLQRQVDAI  60
   61 IVSTSLPPEH PFYQRWANDP FPIVALDRAL DREHFTSVVG ADQDDAEMLA EELRKFPAET 120
  121 VLYLGALPEL SVSFLREQGF RTAWKDDPRE VHFLYANSYE REAAAQLFEK WLETHPMPQA 180
  181 LFTTSFALLQ GVMDVTLRRD GKLPSDLAIA TFGDNELLDF LQCPVLAVAQ RHRDVAERVL 240
  241 EIVLASLDEP RKPKPGLTRI KRNLYRRGVL SRS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.30103
Match:	2iksA
Description:	No description for 2iksA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: