YRC Public Data Repository - Protein Structure Prediction

Protein:	FLAV_ECOLI
Organism:	Escherichia coli
Length:	175 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FLAV_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|117622892, gi... - gi\|117622892\|ref\|YP_851805.1\| flavodoxin FldA [Escherichia coli APEC O1], gi\|115512016\|gb\|ABJ00091.1... gi\|237707346, gi... - gi\|237707346\|ref\|ZP_04537827.1\| flavodoxin FldA [Escherichia sp. 3_2_53FAA], gi\|226898556\|gb\|EEH8481... gi\|26246661, gi\|... - gi\|26246661\|ref\|NP_752701.1\| flavodoxin [Escherichia coli CFT073], gi\|26107060\|gb\|AAN79244.1\|AE01675... gi\|157065844, gi... - gi\|157160164\|ref\|YP_001457482.1\| flavodoxin FldA [Escherichia coli HS], gi\|157065844\|gb\|ABV05099.1\| ... gi\|188495523, gi... - gi\|188495523\|ref\|ZP_03002793.1\| flavodoxin [Escherichia coli 53638], gi\|188490722\|gb\|EDU65825.1\| fla... gi\|157157770, gi... - gi\|157157770\|ref\|YP_001461848.1\| flavodoxin FldA [Escherichia coli E24377A], gi\|157079800\|gb\|ABV1950... gi\|91071301, gi\|... - gi\|91209727\|ref\|YP_539713.1\| flavodoxin FldA [Escherichia coli UTI89], gi\|91071301\|gb\|ABE06182.1\| fl... gi\|110804679, gi... - gi\|110804679\|ref\|YP_688199.1\| flavodoxin FldA [Shigella flexneri 5 str. 8401], gi\|110614227\|gb\|ABF02...	191.0	[0..1]	[175..41]
gi\|146317300, gi... - gi\|75827406\|ref\|ZP_00756841.1\| COG0716: Flavodoxins [Vibrio cholerae O395], gi\|227118546\|ref\|YP_0028... gi\|90074876 - gi\|90074876\|dbj\|BAE87115.1\| flavodoxin 1 [Vibrio cholerae bv. albensis] gi\|15642099, gi\|... - gi\|9656648\|gb\|AAF95245.1\| flavodoxin 1 [Vibrio cholerae O1 biovar El Tor str. N16961], gi\|15642099\|r... gi\|11250201 - pir\|\|A82120 flavodoxin [similarity] - Vibrio cholerae (strain N16961 serogroup O1) gi\|153831270, gi... - gi\|153831270\|ref\|ZP_01983937.1\| flavodoxin 1 [Vibrio cholerae 623-39], gi\|148873250\|gb\|EDL71385.1\| f... gi\|227082225, gi... - gi\|227082225\|ref\|YP_002810776.1\| flavodoxin 1 [Vibrio cholerae M66-2], gi\|227010113\|gb\|ACP06325.1\| f... gi\|229355317, gi... - gi\|229507812\|ref\|ZP_04397317.1\| flavodoxin 1 [Vibrio cholerae BX 330286], gi\|229355317\|gb\|EEO20238.1... gi\|229511951, gi... - gi\|229511951\|ref\|ZP_04401430.1\| flavodoxin 1 [Vibrio cholerae B33], gi\|229351916\|gb\|EEO16857.1\| flav... gi\|254844891, gi... - gi\|254849186\|ref\|ZP_05238536.1\| flavodoxin FldA [Vibrio cholerae MO10], gi\|254844891\|gb\|EET23305.1\| ... gi\|229348935, gi... - gi\|229513754\|ref\|ZP_04403216.1\| flavodoxin 1 [Vibrio cholerae TMA 21], gi\|229348935\|gb\|EEO13892.1\| f... gi\|229519087, gi... - gi\|229519087\|ref\|ZP_04408530.1\| flavodoxin 1 [Vibrio cholerae RC9], gi\|229343776\|gb\|EEO08751.1\| flav... gi\|229522056, gi... - gi\|229522056\|ref\|ZP_04411473.1\| flavodoxin 1 [Vibrio cholerae TM 11079-80], gi\|229340981\|gb\|EEO05986... gi\|229524105, gi... - gi\|229524105\|ref\|ZP_04413510.1\| flavodoxin 1 [Vibrio cholerae bv. albensis VL426], gi\|229337686\|gb\|E... gi\|229332659, gi... - gi\|229528885\|ref\|ZP_04418275.1\| flavodoxin 1 [Vibrio cholerae 12129(1)], gi\|229332659\|gb\|EEN98145.1\|... gi\|229607357, gi... - gi\|229607357\|ref\|YP_002878005.1\| flavodoxin 1 [Vibrio cholerae MJ-1236], gi\|229370012\|gb\|ACQ60435.1\|...	189.0	[0..1]	[174..2]
gi\|88860195, gi\|... - gi\|88860195\|ref\|ZP_01134834.1\| flavodoxin [Pseudoalteromonas tunicata D2], gi\|88818189\|gb\|EAR28005.1...	187.0	[0..1]	[174..2]
gi\|54308229, gi\|... - gi\|54308229\|ref\|YP_129249.1\| flavodoxin FldA [Photobacterium profundum SS9], gi\|46912657\|emb\|CAG1944...	186.0	[0..1]	[174..2]
gi\|21104364 - gi\|21104364\|dbj\|BAB93452.1\| flavodoxin [Actinobacillus actinomycetemcomitans]	185.0	[0..1]	[173..2]
gi\|83584542 - gi\|83584542\|ref\|ZP_00923216.1\| COG0716: Flavodoxins [Escherichia coli 101-1]	185.0	[0..1]	[175..7]
gi\|90327476, gi\|... - gi\|90411586\|ref\|ZP_01219596.1\| flavodoxin [Photobacterium profundum 3TCK], gi\|90327476\|gb\|EAS43829.1...	185.0	[0..1]	[174..2]
gi\|119767337, gi... - gi\|68548445\|ref\|ZP_00587947.1\| Flavodoxin, long chain [Shewanella amazonensis SB2B], gi\|68513842\|gb\|...	185.0	[0..1]	[174..2]
gi\|170521649, gi... - gi\|170683931\|ref\|YP_001742795.1\| flavodoxin [Escherichia coli SMS-3-5], gi\|170521649\|gb\|ACB19827.1\| ... gi\|169888188, gi... - gi\|170080353\|ref\|YP_001729673.1\| flavodoxin 1 [Escherichia coli str. K-12 substr. DH10B], gi\|1698881... gi\|208726492, gi... - gi\|208806691\|ref\|ZP_03249028.1\| flavodoxin [Escherichia coli O157:H7 str. EC4206], gi\|208726492\|gb\|E... gi\|195939409 - gi\|195939409\|ref\|ZP_03084791.1\| flavodoxin FldA [Escherichia coli O157:H7 str. EC4024] gi\|208823273, gi... - gi\|208823273\|ref\|ZP_03263591.1\| flavodoxin [Escherichia coli O157:H7 str. EC4042], gi\|208737466\|gb\|E... gi\|1651291, gi\|8... - gi\|89107542\|ref\|AP_001322.1\| flavodoxin 1 [Escherichia coli str. K-12 substr. W3110], gi\|1651291\|dbj... gi\|208731584, gi... - gi\|208814936\|ref\|ZP_03256115.1\| flavodoxin [Escherichia coli O157:H7 str. EC4045], gi\|208731584\|gb\|E... gi\|13360173, gi\|... - gi\|15829969\|ref\|NP_308742.1\| flavodoxin FldA [Escherichia coli O157:H7 str. Sakai], gi\|13360173\|dbj\|... gi\|209911196, gi... - gi\|209917937\|ref\|YP_002292021.1\| flavodoxin FldA [Escherichia coli SE11], gi\|209911196\|dbj\|BAG76270.... gi\|110640904, gi... - gi\|110640904\|ref\|YP_668632.1\| flavodoxin FldA [Escherichia coli 536], gi\|110342496\|gb\|ABG68733.1\| fl... gi\|209400113, gi... - gi\|209400113\|ref\|YP_002269312.1\| flavodoxin [Escherichia coli O157:H7 str. EC4115], gi\|209161513\|gb\|... FLAV_ECOL6 - Flavodoxin-1 OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=fldA PE=3 SV=2 gi\|168767125, gi... - gi\|189363404\|gb\|EDU81823.1\| flavodoxin [Escherichia coli O157:H7 str. EC4486], gi\|168767125\|ref\|ZP_0... gi\|189355784, gi... - gi\|189355784\|gb\|EDU74203.1\| flavodoxin [Escherichia coli O157:H7 str. EC4401], gi\|168757137\|ref\|ZP_0... gi\|169755898, gi... - gi\|170020970\|ref\|YP_001725924.1\| flavodoxin FldA [Escherichia coli ATCC 8739], gi\|169755898\|gb\|ACA78... gi\|189002975, gi... - gi\|189002975\|gb\|EDU71961.1\| flavodoxin [Escherichia coli O157:H7 str. EC4076], gi\|168779169\|ref\|ZP_0... gi\|218704009, gi... - gi\|218704009\|ref\|YP_002411528.1\| flavodoxin FldA [Escherichia coli UMN026], gi\|218431106\|emb\|CAR1198... gi\|217320861, gi... - gi\|217324640\|ref\|ZP_03440724.1\| flavodoxin [Escherichia coli O157:H7 str. TW14588], gi\|217320861\|gb\|... FLAV_ECOLI - Flavodoxin-1 - Escherichia coli gi\|215485716, gi... - gi\|215485716\|ref\|YP_002328147.1\| flavodoxin FldA [Escherichia coli O127:H6 str. E2348/69], gi\|215263... FLAV_ECOL6 - Flavodoxin-1 OS=Escherichia coli O6 GN=fldA PE=3 SV=2 gi\|218553218, gi... - gi\|218553218\|ref\|YP_002386131.1\| flavodoxin FldA [Escherichia coli IAI1], gi\|218359986\|emb\|CAQ97531.... gi\|30062141, gi\|... - gi\|30062141\|ref\|NP_836312.1\| flavodoxin FldA [Shigella flexneri 2a str. 2457T], gi\|30040386\|gb\|AAP16... gi\|218357288, gi... - gi\|218549747\|ref\|YP_002383538.1\| flavodoxin FldA [Escherichia fergusonii ATCC 35469], gi\|218357288\|e... FLAV_ECO57 - Flavodoxin-1 OS=Escherichia coli O157:H7 GN=fldA PE=3 SV=2 gi\|218426055, gi... - gi\|218688491\|ref\|YP_002396703.1\| flavodoxin FldA [Escherichia coli ED1a], gi\|218426055\|emb\|CAR06872.... EG10318 - flavodoxin 1 / Flavodoxin I gi\|218557613, gi... - gi\|218557613\|ref\|YP_002390526.1\| flavodoxin FldA [Escherichia coli S88], gi\|218364382\|emb\|CAR02061.1... gi\|12513586, gi\|... - gi\|15800387\|ref\|NP_286399.1\| flavodoxin FldA [Escherichia coli O157:H7 EDL933], gi\|12513586\|gb\|AAG55... gi\|124529708, gi... - gi\|124529708\|ref\|ZP_01700615.1\| flavodoxin [Escherichia coli B], gi\|124499711\|gb\|EAY47195.1\| flavodo... gi\|218369025, gi... - gi\|218699039\|ref\|YP_002406668.1\| flavodoxin FldA [Escherichia coli IAI39], gi\|218369025\|emb\|CAR16779... gi\|218350845, gi... - gi\|218694113\|ref\|YP_002401780.1\| flavodoxin FldA [Escherichia coli 55989], gi\|218350845\|emb\|CAU96541... EG10318 - flavodoxin 1 / Flavodoxin I gi\|75189712 - gi\|75189712\|ref\|ZP_00702979.1\| COG0716: Flavodoxins [Escherichia coli E24377A] gi\|227838427, gi... - gi\|227884341\|ref\|ZP_04002146.1\| flavodoxin [Escherichia coli 83972], gi\|227838427\|gb\|EEJ48893.1\| fla... gi\|238861120, gi... - gi\|238899951\|ref\|YP_002925747.1\| flavodoxin 1 [Escherichia coli BW2952], gi\|238861120\|gb\|ACR63118.1\|... gi\|251784174, gi... - gi\|251784174\|ref\|YP_002998478.1\| hypothetical protein B21_00632 [Escherichia coli BL21], gi\|24237644... gi\|74311212, gi\|... - gi\|74311212\|ref\|YP_309631.1\| flavodoxin FldA [Shigella sonnei Ss046], gi\|73854689\|gb\|AAZ87396.1\| fla... gi\|253976847, gi... - gi\|254287540\|ref\|YP_003053288.1\| flavodoxin 1 [Escherichia coli BL21(DE3)], gi\|253976847\|gb\|ACT42517... gi\|82775959, gi\|... - gi\|82775959\|ref\|YP_402306.1\| flavodoxin FldA [Shigella dysenteriae Sd197], gi\|81240107\|gb\|ABB60817.1... gi\|253972653, gi... - gi\|254160752\|ref\|YP_003043860.1\| flavodoxin 1 [Escherichia coli B str. REL606], gi\|253972653\|gb\|ACT3... gi\|75194851 - gi\|75194851\|ref\|ZP_00704921.1\| COG0716: Flavodoxins [Escherichia coli HS] gi\|254591236, gi... - gi\|254791836\|ref\|YP_003076673.1\| flavodoxin 1 [Escherichia coli O157:H7 str. TW14359], gi\|254591236\|... gi\|75227330 - gi\|75227330\|ref\|ZP_00714113.1\| COG0716: Flavodoxins [Escherichia coli B7A]	185.0	[0..1]	[175..2]
gi\|42629140 - gi\|42629140\|ref\|ZP_00154689.1\| COG0716: Flavodoxins [Haemophilus influenzae R2846] gi\|42630494 - gi\|42630494\|ref\|ZP_00156033.1\| COG0716: Flavodoxins [Haemophilus influenzae R2866] gi\|144983098 - gi\|144983098\|gb\|EDJ90598.1\| flavodoxin [Haemophilus influenzae R3021] FLAV_HAEIN - Flavodoxin OS=Haemophilus influenzae GN=fldA PE=3 SV=2 gi\|148827330, gi... - gi\|148827330\|ref\|YP_001292083.1\| flavodoxin FldA [Haemophilus influenzae PittGG], gi\|148718572\|gb\|AB... FLAV_HAEIN - Flavodoxin OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=fldA PE=3 SV=2 gi\|148825543, gi... - gi\|148825543\|ref\|YP_001290296.1\| flavodoxin FldA [Haemophilus influenzae PittEE], gi\|148715703\|gb\|AB... gi\|145271120, gi... - gi\|145639752\|ref\|ZP_01795354.1\| flavodoxin [Haemophilus influenzae PittII], gi\|145271120\|gb\|EDK11035... gi\|68056995, gi\|... - gi\|68248796\|ref\|YP_247908.1\| flavodoxin FldA [Haemophilus influenzae 86-028NP], gi\|68056995\|gb\|AAX87... gi\|145267099, gi... - gi\|145635626\|ref\|ZP_01791323.1\| flavodoxin [Haemophilus influenzae PittAA], gi\|145267099\|gb\|EDK07106... gi\|229811894, gi... - gi\|229845183\|ref\|ZP_04465317.1\| flavodoxin FldA [Haemophilus influenzae 6P18H1], gi\|229811894\|gb\|EEP... gi\|229847366, gi... - gi\|229847366\|ref\|ZP_04467467.1\| flavodoxin FldA [Haemophilus influenzae 7P49H1], gi\|229809692\|gb\|EEP... gi\|144985371, gi... - gi\|145633800\|ref\|ZP_01789524.1\| flavodoxin [Haemophilus influenzae 3655], gi\|144985371\|gb\|EDJ92201.1... gi\|145631313 - gi\|145631313\|ref\|ZP_01787085.1\| flavodoxin [Haemophilus influenzae 22.4-21] gi\|145628492, gi... - gi\|145628492\|ref\|ZP_01784292.1\| flavodoxin [Haemophilus influenzae 22.1-21], gi\|144978962\|gb\|EDJ8864...	184.0	[0..1]	[173..2]

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Predicted Domain #1

Region A:
Residues: [1-175]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AITGIFFGSD TGNTENIAKM IQKQLGKDVA DVHDIAKSSK EDLEAYDILL LGIPTWYYGE  60
   61 AQCDWDDFFP TLEEIDFNGK LVALFGCGDQ EDYAEYFCDA LGTIRDIIEP RGATIVGHWP 120
  121 TAGYHFEASK GLADDDHFVG LAIDEDRQPE LTAERVEKWV KQISEELHLD EILNA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.045757
Match:	1ag9A
Description:	Flavodoxin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	2.0467816962267	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.85486974695416	bayes_pls_golite062009
binding	0.681337940863521	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	0.650874844500866	bayes_pls_golite062009
catalytic activity	0.275631658558537	bayes_pls_golite062009
coenzyme binding	0.265571968246766	bayes_pls_golite062009
protein binding	0.251879151875848	bayes_pls_golite062009
FMN binding	0.056297096581433	bayes_pls_golite062009
cofactor binding	0.0451815885965905	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: