YRC Public Data Repository - Protein Structure Prediction

Protein:	FDRA_ECOLI
Organism:	Escherichia coli
Length:	555 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FDRA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|67932349, gi\|... - gi\|67932349\|ref\|ZP_00525494.1\| GCN5-related N-acetyltransferase:CoA-binding [Solibacter usitatus Ell...	427.0	[0..36]	[553..1]
gi\|68562524, gi\|... - gi\|68562524\|ref\|ZP_00601779.1\| GCN5-related N-acetyltransferase:CoA-binding [Rubrobacter xylanophilu...	422.0	[0..39]	[550..7]
gi\|115368286, gi... - gi\|115374715\|ref\|ZP_01461992.1\| acetyltransferase, gnat family [Stigmatella aurantiaca DW4/3-1], gi\|...	419.0	[0..48]	[553..15]
gi\|75910860, gi\|... - gi\|75910860\|ref\|YP_325156.1\| GCN5-related N-acetyltransferase [Anabaena variabilis ATCC 29413], gi\|7...	416.0	[0..52]	[554..21]
gi\|25533587 - pir\|\|AG1902 acetyl-CoA synthetase [imported] - Nostoc sp. (strain PCC 7120) gi\|17130114, gi\|... - gi\|17228264\|ref\|NP_484812.1\| acetyl-CoA synthetase [Nostoc sp. PCC 7120], gi\|17130114\|dbj\|BAB72726.1...	416.0	[0..52]	[554..21]
gi\|46447204, gi\|... - gi\|46447204\|ref\|YP_008569.1\| hypothetical protein pc1570 [Candidatus Protochlamydia amoebophila UWE2...	411.0	[0..39]	[553..9]
gi\|86553732, gi\|... - gi\|86605190\|ref\|YP_473953.1\| acetyltransferase [Synechococcus sp. JA-3-3Ab], gi\|86553732\|gb\|ABC98690... gi\|86553732, gi\|... - gi\|86605190\|ref\|YP_473953.1\| acetyltransferase, GNAT family [Cyanobacteria bacterium Yellowstone A-P...	409.0	[0..49]	[536..13]
gi\|87288480, gi\|... - gi\|87308769\|ref\|ZP_01090908.1\| GCN5-related N-acetyltransferase [Blastopirellula marina DSM 3645], g...	409.0	[0..53]	[553..4]
gi\|94970033, gi\|... - gi\|94970033\|ref\|YP_592081.1\| CoA-binding protein [Candidatus Koribacter versatilis Ellin345], gi\|945...	407.0	[0..49]	[554..19]
gi\|86607739, gi\|... - gi\|86607739\|ref\|YP_476501.1\| acetyl-CoA synthetase [Cyanobacteria bacterium Yellowstone B-Prime], gi... gi\|86607739, gi\|... - gi\|86607739\|ref\|YP_476501.1\| putative acetyl coenzyme A synthetase [Synechococcus sp. JA-2-3B'a(2-13...	406.0	[0..49]	[537..13]

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Predicted Domain #1

Region A:
Residues: [1-496]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIHAFIKKGC FQDSVSLMII SRKLSESENV DDVSVMMGTP ANKALLDTTG FWHDDFNNAT  60
   61 PNDICVAIRS EAADAGIAQA IMQQLEEALK QLAQGSGSSQ ALTQVRRWDS ACQKLPDANL 120
  121 ALISVAGEYA AELANQALDR NLNVMMFSDN VTLEDEIQLK TRAREKGLLV MGPDCGTSMI 180
  181 AGTPLAFANV MPEGNIGVIG ASGTGIQELC SQIALAGEGI THAIGLGGRD LSREVGGISA 240
  241 LTALEMLSAD EKSEVLAFVS KPPAEAVRLK IVNAMKATGK PTVALFLGYT PAVARDENVW 300
  301 FASSLDEAAR LACLLSRVTA RRNAIAPVSS GFICGLYTGG TLAAEAAGLL AGHLGVEADD 360
  361 THQHGMMLDA DSHQIIDLGD DFYTVGRPHP MIDPTLRNQL IADLGAKPQV RVLLLDVVIG 420
  421 FGATADPAAS LVSAWQKACA ARLDNQPLYA IATVTGTERD PQCRSQQIAT LEDAGIAVVS 480
  481 SLPEATLLAA ALIHPL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	98.30103
Match:	2csuA
Description:	No description for 2csuA was found.

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.37729651093712	bayes_pls_golite062009
oxidoreductase activity	0.68812524232244	bayes_pls_golite062009
ligase activity	0.0165147932430698	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [497-555]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPAAQQHTPS LLENVAVINI GLRSFALELQ SASKPVVHYQ WSPVAGGNKK LARLLERLQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.09691
Match:	1wr2A
Description:	Crystal structure of PH1788 from Pyrococcus horikoshii Ot3
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: