YRC Public Data Repository - Protein Structure Prediction

Protein:	EUTJ_ECOLI
Organism:	Escherichia coli
Length:	278 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EUTJ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|50309731, gi\|... - gi\|50309731\|ref\|XP_454878.1\| unnamed protein product [Kluyveromyces lactis], gi\|49644013\|emb\|CAG9996... gi\|49644013 - gi\|49644013\|emb\|CAG99965.1\| KLLA0E20527p [Kluyveromyces lactis]	293.0	[0..4]	[278..44]
HSP72_CANAL - Heat shock protein SSA2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=SSA2 PE=1 SV=3 HSP72_CANAL - Heat shock protein SSA2 OS=Candida albicans GN=SSA2 PE=1 SV=3 gi\|238879104 - gi\|238879104\|gb\|EEQ42742.1\| heat shock protein SSA2 [Candida albicans WO-1]	293.0	[0..4]	[278..44]
gi\|53829560 - gi\|53829560\|gb\|AAU94659.1\| HSP70 [Rhizophlyctis rosea]	292.0	[0..4]	[278..16]
gi\|4098874 - gi\|4098874\|gb\|AAD00455.1\| heat shock protein 70 [Pneumocystis carinii f. sp. carinii]	291.0	[0..4]	[278..46]
gi\|89329739 - gi\|89329739\|gb\|ABD67499.1\| heat shock protein 70 [Capsaspora owczarzaki]	290.0	[0..4]	[274..46]
gi\|53829562 - gi\|53829562\|gb\|AAU94660.1\| HSP70 [Chytriomyces confervae]	289.0	[0..4]	[278..16]
gi\|44984642 - gi\|44984642\|gb\|AAS53485.1\| AFR114Wp [Ashbya gossypii ATCC 10895] gi\|44984642, gi\|... - gi\|45198632\|ref\|NP_985661.1\| AFR114Wp [Ashbya gossypii ATCC 10895], gi\|44984642\|gb\|AAS53485.1\| AFR11...	289.0	[0..4]	[278..44]
HSP70_NEUCR, HS7... - Heat shock 70 kDa protein OS=Neurospora crassa GN=hsps-1 PE=2 SV=2, (Q01233) Heat shock 70 kDa prote... HSP70_NEUCR - Heat shock 70 kDa protein OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 12...	289.0	[0..4]	[278..44]
gi\|50556910, gi\|... - gi\|50556910\|ref\|XP_505863.1\| YALI0F25289p [Yarrowia lipolytica], gi\|49651733\|emb\|CAG78674.1\| unnamed... gi\|49651733 - gi\|49651733\|emb\|CAG78674.1\| YALI0F25289p [Yarrowia lipolytica]	288.0	[0..4]	[277..45]

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Predicted Domain #1

Region A:
Residues: [1-278]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAHDEQWLTP RLQTAATLCN QTPAATESPL WLGVDLGTCD VVSMVVDRDG QPVAVCLDWA  60
   61 DVVRDGIVWD FFGAVTIVRR HLDTLEQQFG RRFSHAATSF PPGTDPRISI NVLESAGLEV 120
  121 SHVLDEPTAV ADLLQLDNAG VVDIGGGTTG IAIVKKGKVT YSADEATGGH HISLTLAGNR 180
  181 RISLEEAEQY KRGHGEEIWP AVKPVYEKMA DIVARHIEGQ GITDLWLAGG SCMQPGVAEL 240
  241 FRKQFPALQV HLPQHSLFMT PLAIASSGRE KAEGLYAK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.39794
Match:	1nggA
Description:	STRUCTURAL BASIS OF THE 70-KILODALTON HEAT SHOCK COGNATE PROTEIN ATP HYDROLYTIC ACTIVITY, II. STRUCTURE OF THE ACTIVE SITE WITH ADP OR ATP BOUND TO WILD TYPE AND MUTANT ATPASE FRAGMENT
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbohydrate kinase activity	1.0449939978517	bayes_pls_golite062009
catalytic activity	0.666924658593345	bayes_pls_golite062009
hexokinase activity	0.25631236070627	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: