YRC Public Data Repository - Protein Structure Prediction

Protein:	EUTA_ECOLI
Organism:	Escherichia coli
Length:	467 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EUTA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|253978493, gi... - gi\|254289186\|ref\|YP_003054934.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia col... gi\|251785777, gi... - gi\|251785777\|ref\|YP_003000081.1\| hypothetical protein B21_02304 [Escherichia coli BL21], gi\|24237805... gi\|194437597, gi... - gi\|83586901\|ref\|ZP_00925532.1\| COG4819: Ethanolamine utilization protein, possible chaperonin protec... gi\|253974326, gi... - gi\|254162425\|ref\|YP_003045533.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia col...	422.0	[0..1]	[467..1]
gi\|74312976, gi\|... - gi\|74312976\|ref\|YP_311395.1\| reactivating factor for ethanolamine ammonia lyase [Shigella sonnei Ss0...	420.0	[0..1]	[467..1]
gi\|75196456, gi\|... - gi\|75196456\|ref\|ZP_00706526.1\| COG4819: Ethanolamine utilization protein, possible chaperonin protec...	419.0	[0..1]	[467..1]
gi\|240119356, gi... - gi\|240119356\|dbj\|BAH79220.1\| ethanolamine ammonia lyase reactivating factor EutA [Escherichia coli O... gi\|13362783, gi\|... - gi\|15832567\|ref\|NP_311340.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia coli O1... gi\|25340982, gi\|... - pir\|\|D85887 hypothetical protein Z3707 [imported] - Escherichia coli (strain O157:H7, substrain EDL... gi\|15802973, gi\|... - gi\|15802973\|ref\|NP_289003.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia coli O1... gi\|168761050, gi... - gi\|189368428\|gb\|EDU86844.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str. EC4... gi\|189356597, gi... - gi\|189356597\|gb\|EDU75016.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str. EC4... gi\|188017111, gi... - gi\|188017111\|gb\|EDU55233.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str. EC4... gi\|254794395, gi... - gi\|254794395\|ref\|YP_003079232.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia col... gi\|217319985, gi... - gi\|217327618\|ref\|ZP_03443701.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str.... gi\|209400026, gi... - gi\|209400026\|ref\|YP_002271919.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str... gi\|189378546, gi... - gi\|189378546\|gb\|EDU96962.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str. EC5... gi\|189003510, gi... - gi\|189003510\|gb\|EDU72496.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str. EC4... gi\|187770618, gi... - gi\|187770618\|gb\|EDU34462.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str. EC4... gi\|168768533, gi... - gi\|189362182\|gb\|EDU80601.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str. EC4... gi\|208819906, gi... - gi\|208819906\|ref\|ZP_03260226.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str.... gi\|208735434, gi... - gi\|208814157\|ref\|ZP_03255486.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str.... gi\|208729241, gi... - gi\|208809440\|ref\|ZP_03251777.1\| ethanolamine utilization protein EutA [Escherichia coli O157:H7 str.... gi\|195936592 - gi\|195936592\|ref\|ZP_03081974.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia coli...	419.0	[0..1]	[467..1]
gi\|75178044, gi\|... - gi\|75178044\|ref\|ZP_00698103.1\| COG4819: Ethanolamine utilization protein, possible chaperonin protec...	419.0	[0..1]	[467..1]
gi\|110642623, gi... - gi\|110642623\|ref\|YP_670353.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia coli 5...	419.0	[0..1]	[467..1]
gi\|124499623, gi... - gi\|124529763\|ref\|ZP_01700640.1\| Ethanolamine utilisation EutA [Escherichia coli B], gi\|124499623\|gb\|... gi\|169754193, gi... - gi\|170019265\|ref\|YP_001724219.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia col... gi\|193064710, gi... - gi\|75257254\|ref\|ZP_00728778.1\| COG4819: Ethanolamine utilization protein, possible chaperonin protec...	418.0	[0..1]	[467..1]
gi\|115513771, gi... - gi\|117624647\|ref\|YP_853560.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia coli A... gi\|226901331, gi... - gi\|237704965\|ref\|ZP_04535446.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia sp. ... gi\|91211780, gi\|... - gi\|91211780\|ref\|YP_541766.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia coli UT... gi\|218366156, gi... - gi\|218559387\|ref\|YP_002392300.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia col...	418.0	[0..1]	[467..1]
gi\|218352809, gi... - gi\|218696077\|ref\|YP_002403744.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia col... gi\|75187195, gi\|... - gi\|75187195\|ref\|ZP_00700462.1\| COG4819: Ethanolamine utilization protein, possible chaperonin protec...	417.0	[0..1]	[467..1]
gi\|26109224, gi\|... - gi\|26248818\|ref\|NP_754858.1\| reactivating factor for ethanolamine ammonia lyase [Escherichia coli CF... gi\|227835837, gi... - gi\|227887487\|ref\|ZP_04005292.1\| ethanolamine utilization protein EutA [Escherichia coli 83972], gi\|2...	417.0	[0..1]	[467..1]

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Predicted Domain #1

Region A:
Residues: [1-467]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTRQLLSVG IDIGTTTTQV IFSRLELVNR AAVSQVPRYE FIKREISWQS PVFFTPVDKQ  60
   61 GGLKEAELKT LILEQYHAAG IEPESVDSGA IIITGESAKT RNARPAVMAL SQSLGDFVVA 120
  121 SAGPHLESVI AGHGAGAQTL SEQRLCRVLN IDIGGGTANY ALFDAGKISG TACLNVGGRL 180
  181 LETDSHGRVV YAHKPGQMIV DECFGAGTDA RSLTGAQLVQ VTRRMAELIV EVIDGTLSPL 240
  241 AQALMQTGLL PAGVTPEIIT LSGGVGECYR HQPADPFCFA DIGPLLATAL HDHPRLREMN 300
  301 VQFPAQTVRA TVIGAGAHTL SLSGSTIWLE GVQLPLRNLP VAIPIDETDL VGAWQQALIQ 360
  361 LDLDPKTDAY VLALPASLPV RYAAVLTVIN ALVDFVARFP NPHPLLVVAG QDFGKALGML 420
  421 LRPQLQQLPL AVIDEVIVRA GDYIDIGTPL FGGSVVPVTV KSLAFPS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	95.30103
Match:	1yuwA
Description:	crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbohydrate kinase activity	1.0449939978517	bayes_pls_golite062009
catalytic activity	0.666924658593345	bayes_pls_golite062009
hexokinase activity	0.25631236070627	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: