YRC Public Data Repository - Protein Structure Prediction

Protein:	E2F6_MOUSE
Organism:	Mus musculus
Length:	272 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for E2F6_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|34784668, gi\|... - gi\|34784668\|gb\|AAH57929.1\| E2f6 protein [Mus musculus], gi\|17352153\|gb\|AAL38216.1\|AF393249_1 E2F6a [...	352.0	[0..1]	[272..1]
gi\|13874568 - gi\|13874568\|dbj\|BAB46898.1\| hypothetical protein [Macaca fascicularis]	346.0	[0..1]	[272..1]
gi\|109102023 - gi\|109102023\|ref\|XP_001088811.1\| PREDICTED: similar to E2F transcription factor 6 isoform 1 isoform ...	345.0	[0..1]	[272..1]
gi\|109479090 - gi\|109479090\|ref\|XP_001069501.1\| PREDICTED: similar to E2F transcription factor 6 isoform 2 [Rattus ...	341.0	[0..1]	[272..1]
gi\|73980432 - gi\|73980432\|ref\|XP_852463.1\| PREDICTED: similar to E2F transcription factor 6 isoform 1 [Canis famil...	339.0	[0..1]	[272..1]
gi\|114576119 - gi\|114576119\|ref\|XP_001159489.1\| PREDICTED: E2F transcription factor 6 isoform 5 [Pan troglodytes] gi\|208966186, gi... - gi\|60656417\|gb\|AAX32772.1\| E2F transcription factor 6 [synthetic construct], gi\|208966186\|dbj\|BAG731... E2F6 - E2F transcription factor 6	334.0	[0..1]	[260..1]
E2F6_BOVIN - Transcription factor E2F6 OS=Bos taurus GN=E2F6 PE=2 SV=1	329.0	[0..1]	[272..1]

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Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQQRTARRQ PSLLVDPAQE TVRRRCRDPI NVENLLPSKI RINLEENVQY VSMRKALKVK  60
   61 RPRFDVSLVY LTRKFMDLVR SAPGGILDLN KVATKLSVRK RRVYDITNVL DGIELVEKKS 120
  121 KNHIRWIGS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.0
Match:	1cf7A
Description:	Cell cycle transcription factor E2F-4
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [130-272]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLNNFGAAPQ QKKLQAELSD LSAMEDALDE LIKDCAQQLL ELTDDKENER LAYVTYQDIH  60
   61 GIQAFHEQIV IAVKAPEETR LDVPAPREDS ITVHIRSTKG PIDVYLCEVE QNHSNGKTND 120
  121 GIGASPSKSS HPQCPEKEDE PPQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.69897
Match:	2azeB
Description:	Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits