YRC Public Data Repository - Protein Structure Prediction

Protein:	DYR21_ECOLX
Organism:	Escherichia coli
Length:	78 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DYR21_ECOLX.

Description	E-value	Query Range	Subject Range
gi\|190349997, gi... - gi\|75708342\|gb\|ABA26534.1\| DfrIIe [Pseudomonas aeruginosa], gi\|75708339\|gb\|ABA26532.1\| DfrIIe [Pseud...	157.0	[0..1]	[78..1]
gi\|208218 - gi\|208218\|gb\|AAA72259.1\| dihydrofolate reductase	156.0	[0..1]	[76..1]
gi\|72256937, gi\|... - gi\|72256937\|gb\|AAZ67355.1\| hypothetical protein [Escherichia coli], gi\|63146058\|gb\|AAY33960.1\| dihyd... gi\|63146064 - gi\|63146064\|gb\|AAY33965.1\| dihydrofolate reductase [Klebsiella pneumoniae] gi\|24209733 - gi\|24209733\|gb\|AAN41433.1\| dihydrofolate reductase [uncultured bacterium] gi\|71060506 - gi\|71060506\|emb\|CAI56200.1\| dihydrofolate reductase [Bordetella bronchiseptica]	156.0	[0..1]	[78..20]
gi\|215262425 - gi\|215262425\|emb\|CAT00039.1\| dihydrofolate reductase [Aeromonas sobria] gi\|238820137 - gi\|238820137\|gb\|ACR57831.1\| dihydrofolate reductase type II [Klebsiella oxytoca] gi\|321889 - pir\|\|S32183 dihydrofolate reductase (EC 1.5.1.3) type IIc - Klebsiella pneumoniae gi\|1572566, gi\|1... - gi\|7431813\|pir\|\|T08517 dihydrofolate reductase (EC 1.5.1.3), trimethoprim-resistant - Enterobacter a... DYR23_ECOLX - Dihydrofolate reductase type 2 OS=Escherichia coli PE=3 SV=1 gi\|14091020 - gi\|14091020\|gb\|AAK53555.1\|AF327729_1 dihydrofolate reductase [Aeromonas salmonicida subsp. salmonici... gi\|288633, gi\|118972 - gi\|288633\|emb\|CAA51181.1\| dihydrofolate reductase type IIc [Klebsiella aerogenes], sp\|P05794\|DY23_EC...	154.0	[0..1]	[77..1]
gi\|82395940 - gi\|82395940\|gb\|ABB72057.1\| type B dihydrofolate reductase DfrB6 [Salmonella enterica subsp. enterica...	152.0	[0..1]	[78..1]
gi\|215262444 - gi\|215262444\|emb\|CAT00052.1\| dihydrofolate reductase [Aeromonas sobria] gi\|62288200 - gi\|62288200\|gb\|AAX78390.1\| dihydrofolate reductase [Klebsiella pneumoniae] gi\|53988344 - gi\|53988344\|gb\|AAV28212.1\| dihydrofolate reductase [Aeromonas hydrophila] gi\|18478282, gi\|... - gi\|62512105\|gb\|AAX84553.1\| dihydrofolate reductase [Escherichia coli], gi\|194440863\|gb\|ACF70726.1\| t... gi\|126131390 - gi\|126131390\|gb\|ABN79864.1\| dihydrofolate reductase [Aeromonas encheleia]	148.0	[0..1]	[77..1]

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Predicted Domain #1

Region A:
Residues: [1-78]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERSSNEVSN PVAGNFVFPS NATFGMGDRV RKKSGAAWQG QIVGWYCTNL TPEGYAVESE  60
   61 AHPGSVQIYP VAALERIN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.39794
Match:	1vieA
Description:	STRUCTURE OF DIHYDROFOLATE REDUCTASE
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits