YRC Public Data Repository - Protein Structure Prediction

Protein:	DPO4_ECOLI
Organism:	Escherichia coli
Length:	351 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DPO4_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|238793960, gi... - gi\|77978372\|ref\|ZP_00833802.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair...	376.0	[0..1]	[349..1]
gi\|77962907, gi\|... - gi\|77962907\|ref\|ZP_00826722.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair...	371.0	[0..1]	[349..1]
gi\|238784453, gi... - gi\|77957138\|ref\|ZP_00821202.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair...	371.0	[0..1]	[349..1]
gi\|238723882, gi... - gi\|77974373\|ref\|ZP_00829914.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair...	369.0	[0..1]	[349..1]
DPO4_SHIFL - DNA polymerase IV OS=Shigella flexneri GN=dinB PE=3 SV=1 gi\|30061848, gi\|... - gi\|30061848\|ref\|NP_836019.1\| DNA polymerase IV [Shigella flexneri 2a str. 2457T], gi\|30040092\|gb\|AAP... gi\|24050502, gi\|... - gi\|24111721\|ref\|NP_706231.1\| DNA polymerase IV [Shigella flexneri 2a str. 301], gi\|24050502\|gb\|AAN41...	369.0	[0..1]	[351..1]
gi\|190908367, gi... - gi\|75241696\|ref\|ZP_00725533.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair... gi\|237707750, gi... - gi\|237707750\|ref\|ZP_04538231.1\| damage-inducible protein P [Escherichia sp. 3_2_53FAA], gi\|226898960... DPO4_ECOL5 - DNA polymerase IV OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=dinB PE=3 SV=1 gi\|218557187, gi... - gi\|218557187\|ref\|YP_002390100.1\| DNA polymerase IV [Escherichia coli S88], gi\|218363956\|emb\|CAR01621... DPO4_ECOUT - DNA polymerase IV OS=Escherichia coli (strain UTI89 / UPEC) GN=dinB PE=3 SV=1 DPO4_ECOK1 - DNA polymerase IV OS=Escherichia coli O1:K1 / APEC GN=dinB PE=3 SV=1	369.0	[0..1]	[351..1]
DPO4_ECOL6 - DNA polymerase IV OS=Escherichia coli O6 GN=dinB PE=3 SV=1 gi\|227838352, gi... - gi\|227884751\|ref\|ZP_04002556.1\| DNA polymerase IV [Escherichia coli 83972], gi\|227838352\|gb\|EEJ48818... DPO4_ECOL6 - DNA polymerase IV OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=dinB PE=3 SV=1	368.0	[0..1]	[351..1]
gi\|193063270, gi... - gi\|75258764\|ref\|ZP_00730154.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair... gi\|190904210, gi... - gi\|75231167\|ref\|ZP_00717589.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair... gi\|194414401, gi... - gi\|75211199\|ref\|ZP_00711306.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair... DPO4_ECO24 - DNA polymerase IV OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=dinB PE=3 SV=1	368.0	[0..1]	[351..1]
gi\|75237309, gi\|... - gi\|75237309\|ref\|ZP_00721356.1\| COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair... DPO4_ECOHS - DNA polymerase IV OS=Escherichia coli O9:H4 (strain HS) GN=dinB PE=3 SV=1	368.0	[0..1]	[351..1]
gi\|59889801 - gi\|59889801\|emb\|CAH19157.1\| Damage inducible protein P [Escherichia coli] gi\|218703546, gi... - gi\|218703546\|ref\|YP_002411065.1\| DNA polymerase IV [Escherichia coli UMN026], gi\|218430643\|emb\|CAR11...	368.0	[0..1]	[351..1]

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Predicted Domain #1

Region A:
Residues: [1-351]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKIIHVDMD CFFAAVEMRD NPALRDIPIA IGGSRERRGV ISTANYPARK FGVRSAMPTG  60
   61 MALKLCPHLT LLPGRFDAYK EASNHIREIF SRYTSRIEPL SLDEAYLDVT DSVHCHGSAT 120
  121 LIAQEIRQTI FNELQLTASA GVAPVKFLAK IASDMNKPNG QFVITPAEVP AFLQTLPLAK 180
  181 IPGVGKVSAA KLEAMGLRTC GDVQKCDLVM LLKRFGKFGR ILWERSQGID ERDVNSERLR 240
  241 KSVGVERTMA EDIHHWSECE AIIERLYPEL ERRLAKVKPD LLIARQGVKL KFDDFQQTTQ 300
  301 EHVWPRLNKA DLIATARKTW DERRGGRGVR LVGLHVTLLD PQMERQLVLG L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.0
Match:	2asdA
Description:	oxoG-modified Insertion Ternary Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.65300230087591	bayes_pls_golite062009
transferase activity	0.480983365959713	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.454030241998934	bayes_pls_golite062009
nucleotidyltransferase activity	0.422493027411039	bayes_pls_golite062009
DNA polymerase activity	0.170335414417875	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.167944349547235	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: