YRC Public Data Repository - Protein Structure Prediction

Protein:	DHSC_ECOLI
Organism:	Escherichia coli
Length:	129 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DHSC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|29418059 - gi\|29418059\|gb\|AAO39685.1\| succinate dehydrogenase cytochrome b-556 subunit; SdhC [Enterobacter cloa...	137.0	[0..1]	[129..31]
gi\|83372565, gi\|... - gi\|83372565\|ref\|ZP_00917345.1\| similar to Succinate dehydrogenase/fumarate reductase cytochrome b su...	136.0	[0..1]	[128..38]
gi\|161485938 - gi\|161485938\|ref\|NP_706513.2\| succinate dehydrogenase cytochrome b556 large membrane subunit [Shigel... gi\|161486531 - gi\|161486531\|ref\|NP_836287.2\| succinate dehydrogenase cytochrome b556 large membrane subunit [Shigel... gi\|110614199, gi... - gi\|110804651\|ref\|YP_688171.1\| succinate dehydrogenase cytochrome b556 large membrane subunit [Shigel...	134.0	[0..1]	[129..1]
gi\|77972472 - gi\|77972472\|ref\|ZP_00828037.1\| COG2009: Succinate dehydrogenase/fumarate reductase, cytochrome b sub...	134.0	[0..3]	[129..10]
gi\|49077638 - gi\|49077638\|gb\|AAT49701.1\| PA1581 [synthetic construct]	133.0	[0..1]	[129..1]
gi\|194545667, gi... - gi\|254234682\|ref\|ZP_04928005.1\| succinate dehydrogenase (C subunit) [Pseudomonas aeruginosa C3719], ... gi\|115584747, gi... - gi\|116049526\|ref\|YP_791670.1\| succinate dehydrogenase, cytochrome b556 subunit [Pseudomonas aerugino... gi\|218772688, gi... - gi\|218892462\|ref\|YP_002441329.1\| succinate dehydrogenase (C subunit) [Pseudomonas aeruginosa LESB58]... gi\|254239930, gi... - gi\|254239930\|ref\|ZP_04933252.1\| succinate dehydrogenase (C subunit) [Pseudomonas aeruginosa 2192], g... gi\|11352600 - pir\|\|C83448 succinate dehydrogenase (C subunit) PA1581 [imported] - Pseudomonas aeruginosa (strain P... gi\|9947544, gi\|1... - gi\|9947544\|gb\|AAG04970.1\|AE004586_8 succinate dehydrogenase (C subunit) [Pseudomonas aeruginosa PAO1...	133.0	[0..1]	[129..1]
gi\|77961518 - gi\|77961518\|ref\|ZP_00825353.1\| COG2009: Succinate dehydrogenase/fumarate reductase, cytochrome b sub...	131.0	[0..3]	[129..10]
DHSC_SALTI - Succinate dehydrogenase cytochrome b556 subunit OS=Salmonella typhi GN=sdhC PE=3 SV=1 gi\|16759671 - gi\|16759671\|ref\|NP_455288.1\| succinate dehydrogenase cytochrome b556 large membrane subunit [Salmone... DHSC_SALTY - Succinate dehydrogenase cytochrome b556 subunit OS=Salmonella typhimurium (strain LT2 / SGSC1412 / A... gi\|29142556, gi\|... - gi\|29142556\|ref\|NP_805898.1\| succinate dehydrogenase cytochrome b556 large membrane subunit [Salmone... gi\|206707979, gi... - gi\|207856176\|ref\|YP_002242827.1\| succinate dehydrogenase cytochrome b556 large membrane subunit [Sal... gi\|224582547, gi... - gi\|224582547\|ref\|YP_002636345.1\| succinate dehydrogenase cytochrome b556 large membrane subunit [Sal... DHSC_SALTY - Succinate dehydrogenase cytochrome b556 subunit OS=Salmonella typhimurium GN=sdhC PE=3 SV=1 gi\|197363073, gi... - gi\|197363073\|ref\|YP_002142710.1\| succinate dehydrogenase cytochrome b556 large membrane subunit [Sal... DHSC_SALTI - Succinate dehydrogenase cytochrome b556 subunit OS=Salmonella typhi GN=sdhC PE=3 SV=1 gi\|205271777, gi... - gi\|205351996\|ref\|YP_002225797.1\| succinate dehydrogenase cytochrome b556 large membrane subunit [Sal... lcl\|NC_016856.1_... - [gene=sdhC] [protein=succinate dehydrogenase cytochrome b556 large membrane subunit] [protein_id=YP_... gi\|62126940, gi\|... - gi\|62179307\|ref\|YP_215724.1\| succinate dehydrogenase cytochrome b556 large membrane subunit [Salmone... gi\|56128408, gi\|... - gi\|56414151\|ref\|YP_151226.1\| succinate dehydrogenase cytochrome b556 large membrane subunit [Salmone... DHSC_SALTY - Succinate dehydrogenase cytochrome b556 subunit OS=Salmonella typhimurium GN=sdhC PE=3 SV=1	131.0	[0..1]	[129..1]
gi\|77866289, gi\|... - gi\|77954807\|ref\|ZP_00819193.1\| similar to Succinate dehydrogenase/fumarate reductase cytochrome b su...	131.0	[0..4]	[129..50]
gi\|2137070 - gi\|2137070\|pir\|\|I48085 integral membrane protein CII-3 - Chinese hamster (fragment)	130.0	[0..3]	[125..48]

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Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRNVKKQRP VNLDLQTIRF PITAIASILH RVSGVITFVA VGILLWLLGT SLSSPEGFEQ  60
   61 ASAIMGSFFV KFIMWGILTA LAYHVVVGIR HMMMDFGYLE ETFEAGKRSA KISFVITVVL 120
  121 SLLAGVLVW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.045757
Match:	1nekC
Description:	Succinate dehydrogenase subunit SdhC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
succinate dehydrogenase activity	10.6133558935785	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-CH group of donors	7.24661342841192	bayes_pls_golite062009
oxidoreductase activity	5.99989196344185	bayes_pls_golite062009
electron carrier activity	4.50772505551128	bayes_pls_golite062009
binding	1.1076219212629	bayes_pls_golite062009
catalytic activity	0.971825536251904	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: