YRC Public Data Repository - Protein Structure Prediction

Protein:	TBC1D22B
Organism:	Homo sapiens
Length:	505 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TBC1D22B.

Description	E-value	Query Range	Subject Range
TB22B_MACFA - TBC1 domain family member 22B OS=Macaca fascicularis GN=TBC1D22B PE=2 SV=1	0.0	[1..505]	[1..505]
gi\|114607235 - gi\|114607235\|ref\|XP_527375.2\| PREDICTED: TBC1 domain family, member 22B [Pan troglodytes]	0.0	[1..505]	[1..505]
gi\|149643013, gi... - gi\|76650142\|ref\|XP_872801.1\| PREDICTED: similar to TBC1 domain family, member 22B isoform 1 [Bos tau...	0.0	[1..505]	[1..505]
gi\|55728746 - gi\|55728746\|emb\|CAH91112.1\| hypothetical protein [Pongo abelii] gi\|197098566 - gi\|197098566\|ref\|NP_001125650.1\| TBC1 domain family, member 22B [Pongo abelii]	0.0	[1..505]	[1..505]
gi\|37181052, gi\|... - gi\|68163551\|ref\|NP_001020230.1\| TBC1 domain family, member 22B [Rattus norvegicus], gi\|37181052\|gb\|A...	0.0	[1..505]	[1..505]
gi\|149269127, gi... - gi\|94403599\|ref\|XP_998850.1\| PREDICTED: similar to TBC1 domain family, member 22B isoform 3 [Mus mus...	0.0	[1..505]	[1..505]

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Predicted Domain #1

Region A:
Residues: [1-173]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAENSKQFW KRSAKLPGSI QPVYGAQHPP LDPRLTKNFI KERSKVNTVP LKNKKASSFH  60
   61 EFARNTSDAW DIGDDEEEDF SSPSFQTLNS KVALATAAQV LENHSKLRVK PERSQSTTSD 120
  121 VPANYKVIKS SSDAQLSRNS SDTCLRNPLH KQQSLPLRPI IPLVARISDQ NAS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [174-505]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAPPMTVREK TRLEKFRQLL SSQNTDLDEL RKCSWPGVPR EVRPITWRLL SGYLPANTER  60
   61 RKLTLQRKRE EYFGFIEQYY DSRNEEHHQD TYRQIHIDIP RTNPLIPLFQ QPLVQEIFER 120
  121 ILFIWAIRHP ASGYVQGIND LVTPFFVVFL SEYVEEDVEN FDVTNLSQDM LRSIEADSFW 180
  181 CMSKLLDGIQ DNYTFAQPGI QKKVKALEEL VSRIDEQVHN HFRRYEVEYL QFAFRWMNNL 240
  241 LMRELPLRCT IRLWDTYQSE PEGFSHFHLY VCAAFLIKWR KEILDEEDFQ GLLMLLQNLP 300
  301 TIHWGNEEIG LLLAEAYRLK YMFADAPNHY RR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.30103
Match:	2qfzA
Description:	No description for 2qfzA was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits