YRC Public Data Repository - Protein Structure Prediction

Protein:	CENTB5
Organism:	Homo sapiens
Length:	759 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CENTB5.

Description	E-value	Query Range	Subject Range
gi\|12697977 - gi\|12697977\|dbj\|BAB21807.1\| KIAA1716 protein [Homo sapiens]	1.0E-93	[1..713]	[46..758]
gi\|109477804, gi... - gi\|109477804\|ref\|XP_001077851.1\| PREDICTED: similar to centaurin, beta 5 [Rattus norvegicus], gi\|109...	6.0E-91	[1..713]	[43..786]
gi\|46402197, gi\|... - gi\|46402197\|ref\|NP_997106.1\| ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 [Mus musculus]...	9.0E-91	[1..713]	[43..786]
gi\|108995611 - gi\|108995611\|ref\|XP_001093292.1\| PREDICTED: similar to centaurin, beta 5 [Macaca mulatta]	3.0E-89	[1..713]	[139..884]
gi\|76637691 - gi\|76637691\|ref\|XP_593468.2\| PREDICTED: similar to centaurin, beta 5 [Bos taurus]	1.0E-88	[1..713]	[38..781]
gi\|114591214 - gi\|114591214\|ref\|XP_516962.2\| PREDICTED: centaurin, beta 2 [Pan troglodytes]	5.0E-82	[1..732]	[231..931]

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Predicted Domain #1

Region A:
Residues: [1-339]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVEAGKAYVS TSRLFVSGVR DLSQQCQGDT VISECLQRFA DSLQEVVNYH MILFDQAQRS  60
   61 VRQQLQSFVK EDVRKFKETK KQFDKVREDL ELSLVRNAQA PRHRPHEVEE ATGALTLTRK 120
  121 CFRHLALDYV LQINVLQAKK KFEILDSMLS FMHAQSSFFQ QGYSLLHQLD PYMKKLAAEL 180
  181 DQLVIDSAVE KREMERKHAA IQQRTLLQDF SYDESKVEFD VDAPSGVVME GYLFKRASNA 240
  241 FKTWNRRWFS IQNSQLVYQK KLKDALTVVV DDLRLCSVKP CEDIERRFCF EVLSPTKSCM 300
  301 LQADSEKLRQ AWVQAVQASI ASAYRESPDS CYSERLDRT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.522879
Match:	2elbA
Description:	No description for 2elbA was found.

Predicted functions:

Term	Confidence	Notes
binding	2.2415633886751	bayes_pls_golite062009
protein binding	2.07349712211156	bayes_pls_golite062009
phospholipid binding	0.107467402828628	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [340-419]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASPSTSSIDS ATDTRERGVK GESVLQRVQS VAGNSQCGDC GQPDPRWASI NLGVLLCIEC  60
   61 SGIHRSLGVH CSKVRSLTLD

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.98
Match:	2crrA
Description:	Solution structure of ArfGap domain from human SMAP1
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [420-759]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SWEPELLKLM CELGNSAVNQ IYEAQCEGAG SRKPTASSSR QDKEAWIKDK YVEKKFLRKA  60
   61 PMAPALEAPR RWRVQKCLRP HSSPRAPTAR RKVRLEPVLP CVAALSSVGT LDRKFRRDSL 120
  121 FCPDELDSLF SYFDAGAAGA GPRKGAESEE SSGEADGDTE AEAWGLADVR ELHPGLLAHR 180
  181 AARARDLPAL AAALAHGAEV NWADAEDEGK TPLVQAVLGG SLIVCEFLLQ NGADVNQRDS 240
  241 RGRAPLHHAT LLGRTGQVCL FLKRGADQHA LDQEQRDPLA IAVQAANADI VTLLRLARMA 300
  301 EEMREAEAAP GPPGALAGSP TELQFRRCIQ EFISLHLEES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.0
Match:	1n11A
Description:	Ankyrin-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein binding	1.60054179397746	bayes_pls_golite062009
binding	1.55992026787856	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: