YRC Public Data Repository - Protein Structure Prediction

Protein:	CAPZB_CHICK
Organism:	Gallus gallus
Length:	277 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAPZB_CHICK.

Description	E-value	Query Range	Subject Range
CAPZB - capping protein (actin filament) muscle Z-line, beta	523.0	[0..1]	[277..1]
gi\|149024410 - gi\|149024410\|gb\|EDL80907.1\| capping protein (actin filament) muscle Z-line, beta, isoform CRA_b [Rat... CAPZB_MOUSE - F-actin-capping protein subunit beta OS=Mus musculus GN=Capzb PE=1 SV=3	521.0	[0..1]	[277..1]
gi\|55732943\|emb\|... - hypothetical protein [Pongo pygmaeus] gi\|55732943 - gi\|55732943\|emb\|CAH93159.1\| hypothetical protein [Pongo abelii]	512.0	[0..1]	[270..1]
gi\|47229647 - gi\|47229647\|emb\|CAG06843.1\| unnamed protein product [Tetraodon nigroviridis]	507.0	[0..2]	[273..16]
gi\|73950682 - gi\|73950682\|ref\|XP_535384.2\| PREDICTED: similar to F-actin capping protein beta subunit [Canis famil...	503.0	[0..1]	[270..9]
CAPZB_BOVIN - F-actin-capping protein subunit beta OS=Bos taurus GN=CAPZB PE=1 SV=1	502.0	[0..2]	[270..31]
gi\|61365535, gi\|... - gi\|61365535\|gb\|AAX42723.1\| capping protein muscle Z-line beta [synthetic construct], gi\|54695808\|gb\|...	501.0	[0..1]	[270..1]
gi\|148224365, gi... - gi\|148224365\|ref\|NP_001090922.1\| F-actin capping protein subunit beta 2 [Sus scrofa], gi\|118627570\|e... gi\|1079456, gi\|4... - gi\|468204\|gb\|AAA52222.1\| actin capping protein beta subunit, isoform 2, pir\|\|A54819 actin-capping pr... gi\|197129576, gi... - gi\|224080422\|ref\|XP_002192045.1\| PREDICTED: putative actin-capping protein Z beta subunit variant 1 ...	499.0	[0..1]	[270..1]

Back

Predicted Domain #1

Region A:
Residues: [1-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDQQLDCAL DLMRRLPPQQ IEKNLSDLID LVPSLCEDLL SSVDQPLKIA RDKVVGKDYL  60
   61 LCDYNRDGDS YRSPWSNKYD PPLEDGAMPS ARLRKLEVEA NNAFDQYRDL YFEGGVSSVY 120
  121 LWDLDHGFAG VILIKKAGDG SKKIKGCWDS IHVVEVQEKS SGRTAHYKLT STVMLWLQTN 180
  181 KTGSGTMNLG GSLTRQMEKD ETVSDSSPHI ANIGRLVEDM ENKIRSTLNE IYFGKTKDIV 240
  241 NGLRSIDAIP DNQKYKQLQR ELSQVLTQRQ IYIQPDN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	148.0
Match:	1iznB
Description:	Capz beta-1 subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	6.56144513012007	bayes_pls_golite062009
actin filament binding	5.39928513902709	bayes_pls_golite062009
cytoskeletal protein binding	5.10504476256679	bayes_pls_golite062009
binding	2.46279312857752	bayes_pls_golite062009
protein binding	1.31870344025745	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: