YRC Public Data Repository - Protein Structure Prediction

Protein:	BGLB_ECOLI
Organism:	Escherichia coli
Length:	470 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BGLB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|290569 - gi\|290569\|gb\|AAA62072.1\| phospho-beta-glucosidase	510.0	[0..1]	[470..1]
gi\|157163201, gi... - gi\|75197617\|ref\|ZP_00707687.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida...	509.0	[0..1]	[470..1]
gi\|193069174, gi... - gi\|75236450\|ref\|ZP_00720546.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida...	504.0	[0..1]	[464..1]
gi\|157156633, gi... - gi\|75188476\|ref\|ZP_00701743.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida...	504.0	[0..1]	[464..1]
gi\|193063845, gi... - gi\|75258260\|ref\|ZP_00729708.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida... gi\|194428107, gi... - gi\|75210669\|ref\|ZP_00710810.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida...	503.0	[0..1]	[464..1]
gi\|194425453, gi... - gi\|83588414\|ref\|ZP_00927038.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida... gi\|254163673, gi... - gi\|254163673\|ref\|YP_003046781.1\| cryptic phospho-beta-glucosidase B [Escherichia coli B str. REL606]... gi\|253326688, gi... - gi\|254290423\|ref\|YP_003056171.1\| cryptic phospho-beta-glucosidase B [Escherichia coli BL21(DE3)], gi...	503.0	[0..1]	[464..1]
gi\|218354176, gi... - gi\|218697444\|ref\|YP_002405111.1\| cryptic phospho-beta-glucosidase B [Escherichia coli 55989], gi\|218... gi\|191165844, gi... - gi\|75231009\|ref\|ZP_00717444.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida...	501.0	[0..1]	[464..1]
gi\|110345654, gi... - gi\|110644062\|ref\|YP_671792.1\| 6-phospho-beta-glucosidase BglB [Escherichia coli 536], gi\|110345654\|g... gi\|190909376, gi... - gi\|75242491\|ref\|ZP_00726235.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida...	501.0	[0..1]	[464..1]
gi\|218367565, gi... - gi\|218560796\|ref\|YP_002393709.1\| cryptic phospho-beta-glucosidase B [Escherichia coli S88], gi\|21836... gi\|115515118, gi... - gi\|117625994\|ref\|YP_859317.1\| 6-phospho-beta-glucosidase BglB [Escherichia coli APEC O1], gi\|1155151... gi\|91074818, gi\|... - gi\|91213244\|ref\|YP_543230.1\| 6-phospho-beta-glucosidase BglB [Escherichia coli UTI89], gi\|91074818\|g... gi\|237703521, gi... - gi\|237703521\|ref\|ZP_04534002.1\| 6-phospho-beta-glucosidase BglB [Escherichia sp. 3_2_53FAA], gi\|2269...	501.0	[0..1]	[464..1]

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Predicted Domain #1

Region A:
Residues: [1-470]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAFPETFLW GGATAANQVE GAWQEDGKGI STSDLQPHGV MGKMEPRILG KENIKDVAID  60
   61 FYHRYPEDIA LFAEMGFTCL RISIAWARIF PQGDEVEPNE AGLAFYDRLF DEMAQAGIKP 120
  121 LVTLSHYEMP YGLVKNYGGW ANRAVIDHFE HYARTVFTRY QHKVALWLTF NEINMSLHAP 180
  181 FTGVGLAEES GEAEVYQAIH HQLVASARAV KACHSLLPEA KIGNMLLGGL VYPLTCQPQD 240
  241 MLQAMEENRR WMFFGDVQAR GQYPGYMQRF FRDHNITIEM TESDAEDLKH TVDFISFSYY 300
  301 MTGCVSHDES INKNAQGNIL NMIPNPHLKS SEWGWQIDPV GLRVLLNTLW DRYQKPLFIV 360
  361 ENGLGAKDSV EADGSIQDDY RIAYLNDHLV QVNEAIADGV DIMGYTSWGP IDLVSASHSQ 420
  421 MSKRYGFIYV DRDDNGEGSL TRTRKKSFGW YAEVIKTRGL SLKKITIKAP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	124.0
Match:	1qoxA
Description:	Beta-glucosidase A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity, hydrolyzing O-glycosyl compounds	4.55801959095491	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	4.29108420555514	bayes_pls_golite062009
hydrolase activity	2.98140830993539	bayes_pls_golite062009
glucosidase activity	1.92306554001182	bayes_pls_golite062009
catalytic activity	1.85569074294201	bayes_pls_golite062009
alpha-amylase activity	1.42264105957213	bayes_pls_golite062009
amylase activity	1.37652764526134	bayes_pls_golite062009
glycogen debranching enzyme activity	1.37001590940316	bayes_pls_golite062009
hexosaminidase activity	0.763360027922833	bayes_pls_golite062009
alpha-glucosidase activity	0.502835520523619	bayes_pls_golite062009
chitinase activity	0.500233744020165	bayes_pls_golite062009
1,4-alpha-glucan branching enzyme activity	0.47006659934566	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	0.266938437560648	bayes_pls_golite062009
beta-N-acetylhexosaminidase activity	0.263065978664289	bayes_pls_golite062009
binding	0.129334455670168	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: