YRC Public Data Repository - Protein Structure Prediction

Protein:	BAES_ECOLI
Organism:	Escherichia coli
Length:	467 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BAES_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|218427700, gi... - gi\|218690136\|ref\|YP_002398348.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli... gi\|218558958, gi... - gi\|218558958\|ref\|YP_002391871.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli... gi\|26248452, gi\|... - gi\|26248452\|ref\|NP_754492.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli CFT... gi\|237704535, gi... - gi\|237704535\|ref\|ZP_04535016.1\| signal transduction histidine-protein kinase BaeS [Escherichia sp. 3... gi\|115513398, gi... - gi\|117624274\|ref\|YP_853187.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli AP...	310.0	[0..1]	[467..1]
gi\|218554645, gi... - gi\|218554645\|ref\|YP_002387558.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli... gi\|73856079, gi\|... - gi\|74312602\|ref\|YP_311021.1\| signal transduction histidine-protein kinase BaeS [Shigella sonnei Ss04... gi\|81244863, gi\|... - gi\|82543452\|ref\|YP_407399.1\| signal transduction histidine-protein kinase BaeS [Shigella boydii Sb22... gi\|192957432, gi... - gi\|75236273\|ref\|ZP_00720382.1\| COG0642: Signal transduction histidine kinase [Escherichia coli E1100...	310.0	[0..1]	[467..1]
gi\|188015379, gi... - gi\|188015379\|gb\|EDU53501.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4113], gi\|... gi\|168761824, gi... - gi\|189367766\|gb\|EDU86182.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4501], gi\|... gi\|189355116, gi... - gi\|189355116\|gb\|EDU73535.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4401], gi\|... gi\|187768928, gi... - gi\|187768928\|gb\|EDU32772.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4196], gi\|... gi\|189361265, gi... - gi\|189361265\|gb\|EDU79684.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4486], gi\|... gi\|217329666, gi... - gi\|217329666\|ref\|ZP_03445745.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. TW14588]... gi\|254593263, gi... - gi\|254793863\|ref\|YP_003078700.1\| sensory histidine kinase in two-component regulatory system with Ba... gi\|209912801, gi... - gi\|209919542\|ref\|YP_002293626.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli... gi\|226237430 - gi\|226237430\|dbj\|BAH46952.1\| sensory histidine kinase in two-component regulatory system with BaeR [... gi\|15832140, gi\|... - gi\|15832140\|ref\|NP_310913.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli O15... gi\|110615596, gi... - gi\|110806048\|ref\|YP_689568.1\| signal transduction histidine-protein kinase BaeS [Shigella flexneri 5... gi\|218352432, gi... - gi\|218695700\|ref\|YP_002403367.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli... gi\|189371567, gi... - gi\|189371567\|gb\|EDU89983.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC869], gi\|1... gi\|168782365, gi... - gi\|189000163\|gb\|EDU69149.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4076], gi\|... gi\|195938272 - gi\|195938272\|ref\|ZP_03083654.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli ... gi\|168799036, gi... - gi\|189378454\|gb\|EDU96870.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC508], gi\|1... gi\|208730817, gi... - gi\|208817198\|ref\|ZP_03258290.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4045],... gi\|208807194, gi... - gi\|208807194\|ref\|ZP_03249531.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4206],... gi\|209159388, gi... - gi\|209397988\|ref\|YP_002271321.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4115]... gi\|208740522, gi... - gi\|208820399\|ref\|ZP_03260719.1\| sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4042],... gi\|24113460, gi\|... - gi\|24113460\|ref\|NP_707970.1\| signal transduction histidine-protein kinase BaeS [Shigella flexneri 2a... gi\|209747948, gi... - pir\|\|A85835 sensor protein (for BaeR) [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|83571192, gi\|... - gi\|83571192\|ref\|ZP_00922633.1\| COG0642: Signal transduction histidine kinase [Shigella dysenteriae 1... gi\|15832140, gi\|... - gi\|15832140\|ref\|NP_310913.1\| sensor protein for BaeR [Escherichia coli O157:H7], gi\|13362355\|dbj\|BAB... gi\|30063523, gi\|... - gi\|30063523\|ref\|NP_837694.1\| signal transduction histidine-protein kinase BaeS [Shigella flexneri 2a... gi\|15802559, gi\|... - gi\|15802559\|ref\|NP_288586.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli O15...	310.0	[0..1]	[467..1]
gi\|75186875, gi\|... - gi\|75186875\|ref\|ZP_00700142.1\| COG0642: Signal transduction histidine kinase [Escherichia coli E2437...	310.0	[0..1]	[467..1]
gi\|110642288, gi... - gi\|110642288\|ref\|YP_670018.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli 53... gi\|190909753, gi... - gi\|75242900\|ref\|ZP_00726606.1\| COG0642: Signal transduction histidine kinase [Escherichia coli F11],...	309.0	[0..1]	[467..1]
gi\|91072940, gi\|... - gi\|91211366\|ref\|YP_541352.1\| signal transduction histidine-protein kinase BaeS [Escherichia coli UTI...	309.0	[0..1]	[467..1]
gi\|81241563, gi\|... - gi\|82777415\|ref\|YP_403764.1\| signal transduction histidine-protein kinase BaeS [Shigella dysenteriae...	309.0	[0..1]	[467..1]
gi\|75209912, gi\|... - gi\|75209912\|ref\|ZP_00710104.1\| COG0642: Signal transduction histidine kinase [Escherichia coli B171]...	307.0	[0..1]	[467..1]
gi\|75177197, gi\|... - gi\|75177197\|ref\|ZP_00697295.1\| COG0642: Signal transduction histidine kinase [Shigella boydii BS512]...	306.0	[0..1]	[467..1]
gi\|194737114, gi... - gi\|194737114\|ref\|YP_002115221.1\| signal transduction histidine-protein kinase BaeS [Salmonella enter... gi\|168236292, gi... - gi\|197290469\|gb\|EDY29824.1\| signal transduction histidine-protein kinase BaeS [Salmonella enterica s... gi\|238912560 - gi\|238912560\|ref\|ZP_04656397.1\| signal transduction histidine-protein kinase BaeS [Salmonella enteri... gi\|62128335, gi\|... - gi\|62180702\|ref\|YP_217119.1\| signal transduction histidine-protein kinase BaeS [Salmonella enterica ...	298.0	[0..1]	[467..1]

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Predicted Domain #1

Region A:
Residues: [1-147]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFWRPGITG KLFLAIFATC IVLLISMHWA VRISFERGFI DYIKHGNEQR LQLLSDALGE  60
   61 QYAQHGNWRF LRNNDRFVFQ ILRSFEHDNS EDKPGPGMPP HGWRTQFWVV DQNNKVLVGP 120
  121 RAPIPPDGTR RPILVNGAEV GAVIASP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.820	a.7.3	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View	Download	0.522	a.80.1	DNA polymerase III clamp loader subunits, C-terminal domain
View	Download	0.520	a.142.1	PTS-regulatory domain, PRD
View	Download	0.512	a.112.1	Description not found.
View	Download	0.422	c.37.1	P-loop containing nucleoside triphosphate hydrolases

Predicted Domain #2

Region A:
Residues: [148-249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VERLTRNTDI NFDKQQRQTS WLIVALATLL AALATFLLAR GLLAPVKRLV DGTHKLAAGD  60
   61 FTTRVTPTSE DELGKLAQDF NQLASTLEKN QQMRRDFMAD IS

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	4.0
Match:	2f95B
Description:	M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [250-467]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HELRTPLAVL RGELEAIQDG VRKFTPETVA SLQAEVGTLT KLVDDLHQLS MSDEGALAYQ  60
   61 KAPVDLIPLL EVAGGAFRER FASRGLKLQF SLPDSITVFG DRDRLMQLFN NLLENSLRYT 120
  121 DSGGSLQISA GQRDKTVRLT FADSAPGVSD DQLQKLFERF YRTEGSRNRA SGGSGLGLAI 180
  181 CLNIVEAHNG RIIAAHSPFG GVSITVELPL ERDLQREV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.522879
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits