YRC Public Data Repository - Protein Structure Prediction

Protein:	ARGB_THEMA
Organism:	Thermotoga maritima
Length:	282 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARGB_THEMA.

Description	E-value	Query Range	Subject Range
gi\|241883990, gi... - gi\|241903683\|ref\|ZP_04788403.1\| acetylglutamate kinase [Thermoanaerobacter brockii subsp. finnii Ako... ARGB_THEP3 - Acetylglutamate kinase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) GN=argB PE=3...	254.0	[0..2]	[280..10]
gi\|14140161 - gi\|14140161\|emb\|CAC39078.1\| acetylglutamate kinase-like protein [Oryza sativa] gi\|49387584, gi\|... - gi\|50911447\|ref\|XP_467131.1\| unknown protein [Oryza sativa (japonica cultivar-group)], gi\|49388569\|d...	252.0	[0..3]	[278..66]
gi\|255271788, gi... - gi\|255337549\|ref\|ZP_05378427.1\| acetylglutamate kinase [Thermoanaerobacter mathranii subsp. mathrani... ARGB_THEPX - Acetylglutamate kinase OS=Thermoanaerobacter sp. (strain X514) GN=argB PE=3 SV=1 gi\|242256152, gi... - gi\|242256152\|ref\|ZP_04801048.1\| acetylglutamate kinase [Thermoanaerobacter sp. X513], gi\|242232350\|g...	251.0	[0..2]	[280..10]
ARGB_CALS4 - Acetylglutamate kinase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM... ARGB_THETN - Acetylglutamate kinase OS=Thermoanaerobacter tengcongensis GN=argB PE=3 SV=1 gi\|223490027, gi... - gi\|254478171\|ref\|ZP_05091553.1\| acetylglutamate kinase [Carboxydibrachium pacificum DSM 12653], gi\|2...	251.0	[0..2]	[280..10]
ARGB_SYNE7 - Acetylglutamate kinase OS=Synechococcus elongatus (strain PCC 7942) GN=argB PE=1 SV=1 ARGB_SYNP6 - Acetylglutamate kinase OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=argB PE=...	250.0	[0..4]	[278..12]
ARGB_NOSP7 - Acetylglutamate kinase OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=argB PE=3 SV=1	249.0	[0..5]	[277..16]
ARGB_NITMU - Acetylglutamate kinase OS=Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) GN=argB PE=3 SV...	247.0	[0..4]	[278..9]
ARGB_NOSS1 - Acetylglutamate kinase OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=argB PE=3 SV=1 gi\|25288177 - pir\|\|AB1962 acetylglutamate kinase [imported] - Nostoc sp. (strain PCC 7120)	247.0	[0..5]	[277..16]
ARGB_SYNS9 - Acetylglutamate kinase OS=Synechococcus sp. (strain CC9902) GN=argB PE=3 SV=1	247.0	[0..5]	[281..13]
gi\|116072881, gi... - gi\|116072881\|ref\|ZP_01470146.1\| acetylglutamate kinase [Synechococcus sp. BL107], gi\|116064407\|gb\|EA...	247.0	[0..5]	[281..13]

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Predicted Domain #1

Region A:
Residues: [1-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIDTVNVLL EALPYIKEFY GKTFVIKFGG SAMKQENAKK AFIQDIILLK YTGIKPIIVH  60
   61 GGGPAISQMM KDLGIEPVFK NGHRVTDEKT MEIVEMVLVG KINKEIVMNL NLHGGRAVGI 120
  121 CGKDSKLIVA EKETKHGDIG YVGKVKKVNP EILHALIEND YIPVIAPVGI GEDGHSYNIN 180
  181 ADTAAAEIAK SLMAEKLILL TDVDGVLKDG KLISTLTPDE AEELIRDGTV TGGMIPKVEC 240
  241 AVSAVRGGVG AVHIINGGLE HAILLEIFSR KGIGTMIKEL EG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.522879
Match:	2btyA
Description:	Acetylglutamate kinase from Thermotoga maritima complexed with its inhibitor arginine
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetylglutamate kinase activity	3.62493177730942	bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor	3.23203925555954	bayes_pls_golite062009
catalytic activity	3.20382750184555	bayes_pls_golite062009
amino acid kinase activity	2.69040298093296	bayes_pls_golite062009
transferase activity	2.54481238004476	bayes_pls_golite062009
glutamate 5-kinase activity	2.08203900247141	bayes_pls_golite062009
aspartate kinase activity	2.03700691370413	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.89315414622708	bayes_pls_golite062009
kinase activity	1.84529070582231	bayes_pls_golite062009
acetyl-CoA:L-glutamate N-acetyltransferase activity	1.28280910531626	bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity	0.72506602549224	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: