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View Structure Prediction Details

Protein: ADIPOR2
Organism: Homo sapiens
Length: 386 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ADIPOR2.

Description E-value Query
Range
Subject
Range
ADR2_MOUSE - Adiponectin receptor protein 2 OS=Mus musculus GN=Adipor2 PE=1 SV=2
0.0 [1..386] [1..386]
gi|73487235, gi|... - gi|83816891|ref|NP_001033068.1| adiponectin receptor 2 [Rattus norvegicus], gi|73487235|gb|AAZ76714....
0.0 [1..386] [1..386]
gi|109095057, gi... - gi|109095059|ref|XP_001096853.1| PREDICTED: similar to adiponectin receptor 2 isoform 3 [Macaca mula...
0.0 [1..386] [1..386]
gi|73997560, gi|... - gi|73997564|ref|XP_534929.2| PREDICTED: similar to adiponectin receptor 2 isoform 1 [Canis familiari...
0.0 [1..386] [1..386]
gi|48686699, gi|... - gi|55742866|ref|NP_001007193.1| adiponectin receptor 2 [Sus scrofa], gi|48686699|gb|AAT46063.1| adip...
gi|55742866 - ref|NP_001007193.1| adiponectin receptor 2 [Sus scrofa]
0.0 [1..386] [1..386]
gi|81674811, gi|... - gi|94966807|ref|NP_001035589.1| adiponectin receptor 2 [Bos taurus], gi|81674811|gb|AAI10020.1| Adip...
0.0 [1..386] [1..386]
gi|56119026, gi|... - gi|56119026|ref|NP_001007855.1| adiponectin receptor 2 [Gallus gallus], gi|53127374|emb|CAG31070.1| ...
0.0 [1..383] [1..382]
gi|85719404 - gi|85719404|gb|ABC75392.1| adiponectin receptor 2 [Anas platyrhynchos]
0.0 [1..383] [1..382]

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Predicted Domain #1
Region A:
Residues: [1-143]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNEPTENRLG CSRTPEPDIR LRKGHQLDGT RRGDNDSHQG DLEPILEASV LSSHHKKSSE  60
   61 EHEYSDEAPQ EDEGFMGMSP LLQAHHAMEK MEEFVCKVWE GRWRVIPHDV LPDWLKDNDF 120
  121 LLHGHRPPMP SFRACFKSIF RIH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.01
Match: 1rw6A
Description: human APP core domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.48926266746493 bayes_pls_golite062009
DNA binding 1.90797220957918 bayes_pls_golite062009
nucleic acid binding 1.76259159959262 bayes_pls_golite062009
protein binding 1.72899821979103 bayes_pls_golite062009
acetylcholine receptor binding 1.17697499608553 bayes_pls_golite062009
identical protein binding 0.715609885862042 bayes_pls_golite062009
receptor binding 0.362564111690779 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [144-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TETGNIWTHL LGCVFFLCLG IFYMFRPNIS FVAPLQEKVV FGLFFLGAIL CLSFSWLFHT  60
   61 VYCHSEGVSR LFSKLDYSGI ALLIMGSFVP WLYYSFYC

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [242-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPQPCFIYLI VICVLGIAAI IVSQWDMFAT PQYRGVRAGV FLGLGLSGII PTLHYVISEG  60
   61 FLKAATIGQI GWLMLMASLY ITGAALYAAR IPERFFPGKC DIWFHSHQLF HIFVVAGAFV 120
  121 HFHGVSNLQE FRFMIGGGCS EEDAL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle