YRC Public Data Repository - Protein Structure Prediction

Protein:	ADEC_ECOLI
Organism:	Escherichia coli
Length:	588 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ADEC_ECOLI.

Description	E-value	Query Range	Subject Range
ADEC2_CARHZ - Adenine deaminase 2 OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) G...	478.0	[0..15]	[584..2]
ADEC_SHISS - Adenine deaminase OS=Shigella sonnei (strain Ss046) GN=ade PE=3 SV=1	473.0	[0..1]	[588..1]
ADEC_ECOL6 - Adenine deaminase OS=Escherichia coli O6 GN=ade PE=3 SV=1 ADEC_ECOL6 - Adenine deaminase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=ade PE=3 SV=1 gi\|227883887, gi... - gi\|227883887\|ref\|ZP_04001692.1\| cryptic adenine deaminase [Escherichia coli 83972], gi\|227839165\|gb\|...	472.0	[0..1]	[588..1]
ADEC_ECO81 - Adenine deaminase OS=Escherichia coli O81 (strain ED1a) GN=ade PE=3 SV=1 ADEC_ECOL5 - Adenine deaminase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=ade PE=3 SV=1 gi\|190909208, gi... - gi\|75242539\|ref\|ZP_00726283.1\| COG1001: Adenine deaminase [Escherichia coli F11], gi\|191170400\|ref\|Z...	472.0	[0..1]	[588..1]
gi\|75236390 - gi\|75236390\|ref\|ZP_00720486.1\| COG1001: Adenine deaminase [Escherichia coli E110019]	471.0	[0..1]	[588..1]
ADEC_ECO45 - Adenine deaminase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=ade PE=3 SV=1 ADEC_ECOUT - Adenine deaminase OS=Escherichia coli (strain UTI89 / UPEC) GN=ade PE=3 SV=1 gi\|237703469, gi... - gi\|237703469\|ref\|ZP_04533950.1\| cryptic adenine deaminase [Escherichia sp. 3_2_53FAA], gi\|226902733\|... ADEC_ECOK1 - Adenine deaminase OS=Escherichia coli O1:K1 / APEC GN=ade PE=3 SV=1	471.0	[0..1]	[588..1]
ADEC_ECO57 - Adenine deaminase OS=Escherichia coli O157:H7 GN=ade PE=3 SV=1 gi\|217325122, gi... - gi\|217325122\|ref\|ZP_03441206.1\| adenine deaminase [Escherichia coli O157:H7 str. TW14588], gi\|217321... gi\|209754402, gi... - pir\|\|D86050 probable adenine deaminase (synthesis xanthine) yicP [imported] - Escherichia coli (stra... gi\|208808580, gi... - gi\|208808580\|ref\|ZP_03250917.1\| adenine deaminase [Escherichia coli O157:H7 str. EC4206], gi\|2087283... gi\|15804261, gi\|... - gi\|15804261\|ref\|NP_290300.1\| cryptic adenine deaminase [Escherichia coli O157:H7 EDL933], gi\|1251849... gi\|208814131, gi... - gi\|208814131\|ref\|ZP_03255460.1\| adenine deaminase [Escherichia coli O157:H7 str. EC4045], gi\|2087354... gi\|208819901, gi... - gi\|208819901\|ref\|ZP_03260221.1\| adenine deaminase [Escherichia coli O157:H7 str. EC4042], gi\|2087400... ADEC_ECO5E - Adenine deaminase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=ade PE=3 SV=1 gi\|168779883, gi... - gi\|189002484\|gb\|EDU71470.1\| adenine deaminase [Escherichia coli O157:H7 str. EC4076], gi\|168779883\|r... gi\|189374661, gi... - gi\|189374661\|gb\|EDU93077.1\| adenine deaminase [Escherichia coli O157:H7 str. EC869], gi\|168785616\|re... gi\|168798697, gi... - gi\|189378861\|gb\|EDU97277.1\| adenine deaminase [Escherichia coli O157:H7 str. EC508], gi\|168798697\|re... gi\|195936284 - gi\|195936284\|ref\|ZP_03081666.1\| cryptic adenine deaminase [Escherichia coli O157:H7 str. EC4024] gi\|189358902, gi... - gi\|189358902\|gb\|EDU77321.1\| adenine deaminase [Escherichia coli O157:H7 str. EC4401], gi\|168753551\|r... gi\|168759848, gi... - gi\|189369627\|gb\|EDU88043.1\| adenine deaminase [Escherichia coli O157:H7 str. EC4501], gi\|168759848\|r... gi\|189364740, gi... - gi\|189364740\|gb\|EDU83159.1\| adenine deaminase [Escherichia coli O157:H7 str. EC4486], gi\|168766148\|r... gi\|168772303, gi... - gi\|187771707\|gb\|EDU35551.1\| adenine deaminase [Escherichia coli O157:H7 str. EC4196], gi\|168772303\|r... gi\|13364077, gi\|... - gi\|15833856\|ref\|NP_312629.1\| cryptic adenine deaminase [Escherichia coli O157:H7 str. Sakai], gi\|133... gi\|188016895, gi... - gi\|188016895\|gb\|EDU55017.1\| adenine deaminase [Escherichia coli O157:H7 str. EC4113], gi\|168748622\|r... gi\|254595073, gi... - gi\|254795673\|ref\|YP_003080510.1\| cryptic adenine deaminase [Escherichia coli O157:H7 str. TW14359], ...	471.0	[0..1]	[588..1]
ADEC_ECOHS - Adenine deaminase OS=Escherichia coli O9:H4 (strain HS) GN=ade PE=3 SV=1	469.0	[0..1]	[588..1]
ADEC_ECOLC - Adenine deaminase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=ade PE=3 SV=1 gi\|188493641, gi... - gi\|75514268\|ref\|ZP_00736576.1\| COG1001: Adenine deaminase [Escherichia coli 53638], gi\|188493641\|ref... gi\|190904186, gi... - gi\|75231065\|ref\|ZP_00717500.1\| COG1001: Adenine deaminase [Escherichia coli B7A], gi\|191165862\|ref\|Z... gi\|124500155, gi... - gi\|124529016\|ref\|ZP_01700162.1\| adenine deaminase [Escherichia coli B], gi\|124500155\|gb\|EAY47632.1\| ... ADEC_ECO8A - Adenine deaminase OS=Escherichia coli O8 (strain IAI1) GN=ade PE=3 SV=1 ADEC_ECO55 - Adenine deaminase OS=Escherichia coli (strain 55989 / EAEC) GN=ade PE=3 SV=1	468.0	[0..1]	[588..1]
ADEC_SHIFL - Adenine deaminase OS=Shigella flexneri GN=ade PE=3 SV=1 gi\|24054275, gi\|... - gi\|24115019\|ref\|NP_709529.1\| cryptic adenine deaminase [Shigella flexneri 2a str. 301], gi\|24054275\|... gi\|30064978, gi\|... - gi\|30064978\|ref\|NP_839149.1\| cryptic adenine deaminase [Shigella flexneri 2a str. 2457T], gi\|3004323...	468.0	[0..1]	[588..1]

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Predicted Domain #1

Region A:
Residues: [1-435]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNSINHKFH HISRAEYQEL LAVSRGDAVA DYIIDNVSIL DLINGGEISG PIVIKGRYIA  60
   61 GVGAEYTDAP ALQRIDARGA TAVPGFIDAH LHIESSMMTP VTFETATLPR GLTTVICDPH 120
  121 EIVNVMGEAG FAWFARCAEQ ARQNQYLQVS SCVPALEGCD VNGASFTLEQ MLAWRDHPQV 180
  181 TGLAEMMDYP GVISGQNALL DKLDAFRHLT LDGHCPGLGG KELNAYITAG IENCHESYQL 240
  241 EEGRRKLQLG MSLMIREGSA ARNLNALAPL INEFNSPQCM LCTDDRNPWE IAHEGHIDAL 300
  301 IRRLIEQHNV PLHVAYRVAS WSTARHFGLN HLGLLAPGKQ ADIVLLSDAR KVTVQQVLVK 360
  361 GEPIDAQTLQ AEESARLAQS APPYGNTIAR QPVSASDFAL QFTPGKRYRV IDVIHNELIT 420
  421 HSHSSVYSEN GFDRD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.221849
Match:	1ef2A
Description:	alpha-Subunit of urease; alpha-subunit of urease, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [436-588]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVSFIAVLER YGQRLAPACG LLGGFGLNEG ALAATVSHDS HNIVVIGRSA EEMALAVNQV  60
   61 IQDGGGLCVV RNGQVQSHLP LPIAGLMSTD TAQSLAEQID ALKAAARECG PLPDEPFIQM 120
  121 AFLSLPVIPA LKLTSQGLFD GEKFAFTTLE VTE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.634	0.930	manganese ion binding	c.55.3	Ribonuclease H-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits