YRC Public Data Repository - Protein Structure Prediction

Protein:	ACEA_ECOLI
Organism:	Escherichia coli
Length:	434 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACEA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|26111215, gi\|... - gi\|26250784\|ref\|NP_756824.1\| isocitrate lyase [Escherichia coli CFT073], gi\|26111215\|gb\|AAN83398.1\|A...	527.0	[0..1]	[434..6]
gi\|110807859, gi... - gi\|110807859\|ref\|YP_691379.1\| isocitrate lyase [Shigella flexneri 5 str. 8401], gi\|110617407\|gb\|ABF0...	527.0	[0..1]	[434..1]
gi\|217326544, gi... - gi\|217326544\|ref\|ZP_03442628.1\| isocitrate lyase [Escherichia coli O157:H7 str. TW14588], gi\|2173227... gi\|209159761, gi... - gi\|209398361\|ref\|YP_002273527.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4115], gi\|2091597... gi\|208820415, gi... - gi\|208820415\|ref\|ZP_03260735.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4042], gi\|20874053... gi\|208734555, gi... - gi\|208813278\|ref\|ZP_03254607.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4045], gi\|20873455... gi\|189001768, gi... - gi\|189001768\|gb\|EDU70754.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4076], gi\|168780397\|re... gi\|187769880, gi... - gi\|187769880\|gb\|EDU33724.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4196], gi\|168774341\|re... gi\|168766245, gi... - gi\|189363894\|gb\|EDU82313.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4486], gi\|168766245\|re... gi\|189368595, gi... - gi\|189368595\|gb\|EDU87011.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4501], gi\|168760849\|re... gi\|208726481, gi... - gi\|208806680\|ref\|ZP_03249017.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4206], gi\|20872648... gi\|195935773 - gi\|195935773\|ref\|ZP_03081155.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4024] gi\|168798354, gi... - gi\|189379201\|gb\|EDU97617.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC508], gi\|168798354\|ref... gi\|189375064, gi... - gi\|189375064\|gb\|EDU93480.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC869], gi\|168784599\|ref... gi\|25291165 - pir\|\|E91245 isocitrate lyase [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952) gi\|13364409, gi\|... - gi\|15834187\|ref\|NP_312960.1\| isocitrate lyase [Escherichia coli O157:H7 str. Sakai], gi\|13364409\|dbj... gi\|189357472, gi... - gi\|189357472\|gb\|EDU75891.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4401], gi\|168755154\|re... gi\|188015036, gi... - gi\|188015036\|gb\|EDU53158.1\| isocitrate lyase [Escherichia coli O157:H7 str. EC4113], gi\|168750866\|re... gi\|13364409, gi\|... - gi\|15834187\|ref\|NP_312960.1\| isocitrate lyase [Escherichia coli O157:H7], gi\|13364409\|dbj\|BAB38356.1... gi\|254595408, gi... - gi\|254796008\|ref\|YP_003080845.1\| isocitrate lyase [Escherichia coli O157:H7 str. TW14359], gi\|254595...	527.0	[0..1]	[434..1]
gi\|75514777 - gi\|75514777\|ref\|ZP_00737006.1\| COG2224: Isocitrate lyase [Escherichia coli 53638] gi\|227836130, gi... - gi\|227886989\|ref\|ZP_04004794.1\| isocitrate lyase [Escherichia coli 83972], gi\|227836130\|gb\|EEJ46596.... gi\|75258934 - gi\|75258934\|ref\|ZP_00730302.1\| COG2224: Isocitrate lyase [Escherichia coli E22] gi\|75241041 - gi\|75241041\|ref\|ZP_00724915.1\| COG2224: Isocitrate lyase [Escherichia coli F11] gi\|75238552 - gi\|75238552\|ref\|ZP_00722541.1\| COG2224: Isocitrate lyase [Escherichia coli E110019] gi\|75229420 - gi\|75229420\|ref\|ZP_00715972.1\| COG2224: Isocitrate lyase [Escherichia coli B7A] gi\|75211897 - gi\|75211897\|ref\|ZP_00711952.1\| COG2224: Isocitrate lyase [Escherichia coli B171] gi\|75197874 - gi\|75197874\|ref\|ZP_00707944.1\| COG2224: Isocitrate lyase [Escherichia coli HS] gi\|75188740 - gi\|75188740\|ref\|ZP_00702007.1\| COG2224: Isocitrate lyase [Escherichia coli E24377A] gi\|83587110 - gi\|83587110\|ref\|ZP_00925739.1\| COG2224: Isocitrate lyase [Escherichia coli 101-1]	527.0	[0..1]	[434..6]
gi\|15826516, gi\|... - gi\|15826517\|pdb\|1IGW\|D Chain D, Crystal Structure Of The Isocitrate Lyase From The A219c Mutant Of E...	527.0	[0..1]	[434..1]
gi\|62130266, gi\|... - gi\|62182633\|ref\|YP_219050.1\| isocitrate lyase [Salmonella enterica subsp. enterica serovar Choleraes...	527.0	[0..1]	[434..1]
gi\|91213527, gi\|... - gi\|91213527\|ref\|YP_543513.1\| isocitrate lyase [Escherichia coli UTI89], gi\|91075101\|gb\|ABE09982.1\| i... gi\|115515400, gi... - gi\|117626276\|ref\|YP_859599.1\| isocitrate lyase [Escherichia coli APEC O1], gi\|115515400\|gb\|ABJ03475.... gi\|226901473, gi... - gi\|237703561\|ref\|ZP_04534042.1\| isocitrate lyase [Escherichia sp. 3_2_53FAA], gi\|226901473\|gb\|EEH877...	527.0	[0..1]	[434..6]
gi\|197364933, gi... - gi\|197364933\|ref\|YP_002144570.1\| isocitrate lyase [Salmonella enterica subsp. enterica serovar Parat... gi\|194448662, gi... - gi\|194448662\|ref\|YP_002048167.1\| isocitrate lyase [Salmonella enterica subsp. enterica serovar Heide... gi\|194443373, gi... - gi\|194443373\|ref\|YP_002043428.1\| isocitrate lyase [Salmonella enterica subsp. enterica serovar Newpo... gi\|168243570, gi... - gi\|205337380\|gb\|EDZ24144.1\| isocitrate lyase [Salmonella enterica subsp. enterica serovar Heidelberg... gi\|238913068 - gi\|238913068\|ref\|ZP_04656905.1\| isocitrate lyase [Salmonella enterica subsp. enterica serovar Tennes... gi\|56130263, gi\|... - gi\|56416006\|ref\|YP_153081.1\| isocitrate lyase [Salmonella enterica subsp. enterica serovar Paratyphi...	526.0	[0..1]	[434..1]
gi\|25291163 - pir\|\|C86093 isocitrate lyase [imported] - Escherichia coli (strain O157:H7, substrain EDL933) gi\|15804601, gi\|... - gi\|15804601\|ref\|NP_290642.1\| isocitrate lyase [Escherichia coli O157:H7 EDL933], gi\|12518945\|gb\|AAG5...	526.0	[0..1]	[434..6]
gi\|75179629 - gi\|75179629\|ref\|ZP_00699633.1\| COG2224: Isocitrate lyase [Shigella boydii BS512]	526.0	[0..1]	[434..6]

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Predicted Domain #1

Region A:
Residues: [1-434]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTRTQQIEE LQKEWTQPRW EGITRPYSAE DVVKLRGSVN PECTLAQLGA AKMWRLLHGE  60
   61 SKKGYINSLG ALTGGQALQQ AKAGIEAVYL SGWQVAADAN LAASMYPDQS LYPANSVPAV 120
  121 VERINNTFRR ADQIQWSAGI EPGDPRYVDY FLPIVADAEA GFGGVLNAFE LMKAMIEAGA 180
  181 AAVHFEDQLA SVKKCGHMGG KVLVPTQEAI QKLVAARLAA DVTGVPTLLV ARTDADAADL 240
  241 ITSDCDPYDS EFITGERTSE GFFRTHAGIE QAISRGLAYA PYADLVWCET STPDLELARR 300
  301 FAQAIHAKYP GKLLAYNCSP SFNWQKNLDD KTIASFQQQL SDMGYKFQFI TLAGIHSMWF 360
  361 NMFDLANAYA QGEGMKHYVE KVQQPEFAAA KDGYTFVSHQ QEVGTGYFDK VTTIIQGGTS 420
  421 SVTALTGSTE ESQF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	150.0
Match:	1igwA
Description:	Isocitrate lyase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits