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View Structure Prediction Details

Protein: wrt-6
Organism: Caenorhabditis elegans
Length: 593 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for wrt-6.

Description E-value Query
Range
Subject
Range
gi|39597745, gi|... - gi|39597745|emb|CAE68437.1| Hypothetical protein CBG14222 [Caenorhabditis briggsae], gi|187027750|em...
gi|157769189 - gi|157769189|ref|XP_001676415.1| Hypothetical protein CBG14222 [Caenorhabditis briggsae AF16]
444.0 [0..2] [593..3]

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Predicted Domain #1
Region A:
Residues: [1-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLLNLFYCF CLLFGAVLAD SIHDGGSCGT NSIPYKMEVD SEGKPVISCE APSCLGVSSS  60
   61 AARRPRVLDV SCDPFKEIVC VKDLQWTSGL VEINNGTHRT LKTECCSYEG MSDAKTIKSI 120
  121 FLGPGQSFVG GMVEKDGEQS GFDLIKEIRK TVNADNQVQY IVGVYRMPCE ATSDSSEEAL 180
  181 PLLSRNRRKL R

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [192-368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRVGKYDDYE EDRNYRSERR RPFAMRRRAL LQRLEDMYDD YDYEFRVVRR PFRKSRLPYN  60
   61 ENALWPLQYS SPQRSRTFAD NTYNKETVES GPLPPPPSSN YIDNVAPASP VVQSPAYPQT 120
  121 PAEMPLPPQS GSYSGSYSGY PTADASQYNA YPAMQQPAYQ PAYQPAYQPA YQPAYQP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [369-593]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYQPAYSARG YSPNLNGLFG GTGMQCFSGD MEVETEDGIK MIKDLKIGDK VLSMDEAFVT  60
   61 YSPVIMFLHK RDEEIAEFNL IETANGHSIK LTDNHLIYVS DCRTRSDLKL VAAKEVKMDD 120
  121 CIHVTTDSNV VIKKKVSKIS KVIETGIYSP LTSTGDIIVN RVLASCHSNL ALKSLQQTFF 180
  181 SLYKRTSSVF HNLMFFKSST EEGDLPVGVE TLTSVMDLFI PQSFV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.522879
Match: 1at0A
Description: 17-KDA FRAGMENT OF HEDGEHOG C-TERMINAL AUTOPROCESSING DOMAIN
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle