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View Structure Prediction Details

Protein: mtm-9
Organism: Caenorhabditis elegans
Length: 521 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mtm-9.

Description E-value Query
Range
Subject
Range
gi|114639938 - gi|114639938|ref|XP_001146719.1| PREDICTED: myotubularin-related protein 2 isoform 5 [Pan troglodyte...
630.0 [0..9] [517..165]

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Predicted Domain #1
Region A:
Residues: [1-521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELSELIEVT RVRDAFMRKG PRPAQVGDIC IFGHHLIFAP TTVGKEVPDN AEEFWLLHKA  60
   61 VDRVLYGFLH DYAFFYNSPF TILDDGWSAF DLEQEFARLM LSTDAFRISS VNENFAICPT 120
  121 YPEKLIVPKG IGDDYLKISA TFREGGRFPV LSYFHKETKS PLVRCSQPLI GPTNRRCRED 180
  181 ETILNSMITV NRGYIIDTRS KSSATAAKAK GGGAEPQGNY RQWRYIQCPI PRQREIHDAL 240
  241 TRMVDVCSER KVTSDRWVSR VGQAGWLSSV AASLEAAANV AQCIYNERLE EVPVVIHGGD 300
  301 GLDSTLIASS LAQILLDADA RTIRGFESVI EREWICGGHP FSLRNNHCAY AEGTVTGPFE 360
  361 SPVFLVFLDA VHQMIAQYPM SFEFDENFLI FLFEHAYASE FGSFLGNCEK EKKDNGIRKK 420
  421 TVSLWSHVHH PENMKQFVNV CYDPTPGVIW PSIAPQCIKI WDRLFFRWQR PDNSWSTPET 480
  481 ETIQSLADHW KLREKELIAK ASSLRRSVVE LSRELRVLSP M

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 180.0
Match: 1lw3A
Description: Crystal Structure of Myotubularin-related protein 2 complexed with phosphate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrolase activity 1.38649318954561 bayes_pls_golite062009
protein binding 1.02623199121506 bayes_pls_golite062009
binding 1.01091307698013 bayes_pls_golite062009
phosphoprotein phosphatase activity 0.745623131891915 bayes_pls_golite062009
phosphatase activity 0.713516268284312 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.690017820679101 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.595509970131394 bayes_pls_golite062009
catalytic activity 0.520226245445552 bayes_pls_golite062009
protein tyrosine phosphatase activity 0.180095138704027 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle