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View Structure Prediction Details

Protein: dab-1
Organism: Caenorhabditis elegans
Length: 490 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dab-1.

Description E-value Query
Range
Subject
Range
gi|25354045 - gi|25354045|pir||A88230 protein M110.5 [imported] - Caenorhabditis elegans
303.0 [0..1] [490..57]

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Predicted Domain #1
Region A:
Residues: [1-192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQKSDISVE TANATSGKPN PPSPKSRLAM LKRTKKASNA SSDPFRFQNN GISYKGKLIG  60
   61 EQDVDKARGD AMCAEAMRTA KSIIKAAGAH KTRITLQINI DGIKVLDEKS GAVLHNFPVS 120
  121 RISFIARDSS DARAFGLVYG EPGGKYKFYG IKTAQAADQA VLAIRDMFQV VFEMKKKQIE 180
  181 QVKQQQIQDG GA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.221849
Match: 1oqnA
Description: Crystal structure of the phosphotyrosine binding domain (PTB) of mouse Disabled 1 (Dab1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.75270183218429 bayes_pls_golite062009
protein binding 1.30337811957526 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [193-305]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EISSKKEGGV AVADLLDLES ELQQIERGVQ QLSTVPTNCD AFGASPFGDP FVDSFNSTAT  60
   61 SNGTANMSGT QVPFGGLQLP QVQQMQMPMV QIPQQSHQNW PTSGAGSFDA WGQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [306-490]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQQQQQMHHA HSTPAFGTNG FSDTNPFASA FNTQARPPPL PTVAPTQYRD PFSVHSSAIP  60
   61 NSNIDWTGTG TTKENMAPST NIQQQQSSLH HASTFANFGD NKAETWSEKK VTSLEEAFTK 120
  121 LVDMDALVGG QGIKETKKNP FEHILNPPKA SLNSMSTTCS AAQMAATQQH TTSSHADPFG 180
  181 DDFFR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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