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View Structure Prediction Details

Protein: nas-11
Organism: Caenorhabditis elegans
Length: 579 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-11.

Description E-value Query
Range
Subject
Range
gi|39586736, gi|... - gi|39586736|emb|CAE65778.1| Hypothetical protein CBG10873 [Caenorhabditis briggsae], gi|187030660|em...
gi|157770282 - gi|157770282|ref|XP_001676961.1| Hypothetical protein CBG10873 [Caenorhabditis briggsae AF16]
624.0 [0..1] [578..1]

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Predicted Domain #1
Region A:
Residues: [1-51]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPSLVFLIV VIVVVEGQGW RPWDRFNHPG NFGNWGGNNW GTRQRNQEPH D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [52-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IPPPVPPPGF RGNNDRFGGN IIKVVEIIDL GKSKNRGDIL SDFKDVHKKH RHLGRKEWKG  60
   61 KVKQFCHRFP GHPNCRRGKV PDQKELEEMI GQFSKGGIGR FLKRVPKIYI EDPLARVDPK 120
  121 LKGFLENAGR GFGHVSSEHV NKLRDICKRR KCREQPESAK KTRELFTQKL ADFETKIAGK 180
  181 DKTDSVQLRF DRTLQIKEAL LEKGNLTADI VPVDNGVYDL DTML

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [276-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TEEQANILLN ELNKAGVGDD EIPLPDADTD DEDDDDSTNS ASGAAPGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 1su3A
Description: X-ray structure of human proMMP-1: New insights into collagenase action
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [324-579]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRLKKSALYF EGNLIKKWDP SSPIRYVLDS SLEDLDKNDV RAAIYEIEKN TCIRFKELSS  60
   61 PPTGSHIVYY KVDSPTFCGL SYVGRADPAN PVYLSFGCDN NKGVAIHETM HALGVAHQHL 120
  121 RNDRDQFITI NWSNIDPQQY DAFVVVDSKL YTSYGVKYAY DSIMHYNGYT AAQNIAIPTM 180
  181 NPKTNSAVNL KVLGQRQKMG TTDIELLKKM YCQPGCDDKN VYCGAWALKD LCKNPGHDQY 240
  241 MAANCKKSCG LCAIGK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.154902
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.448845530777411 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle