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View Structure Prediction Details

Protein: acr-18
Organism: Caenorhabditis elegans
Length: 510 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-18.

Description E-value Query
Range
Subject
Range
gi|73974924 - gi|73974924|ref|XP_539232.2| PREDICTED: similar to cholinergic receptor, nicotinic, alpha polypeptid...
406.0 [0..26] [492..101]

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Predicted Domain #1
Region A:
Residues: [1-354]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIYPCFLIL WQILSSHRVH ATSHPARTPM RNLYEHLFLD YVKEIRPVRN ESESLKVEIK  60
   61 FWLKQILKVD ERDQIVNIYC WLELYWIDET LTWDPKKFGN LSRIHVPAHK IWKPDVLVYN 120
  121 NANMNVEENE METNAIVDNT GRVMLFRSMI TDISCNLNLQ QFPFDQQICF VTFASWSMDG 180
  181 SKLDLSATPK TDNLELYIRN TEWGLTDFRV KIYQKIYDCC PHPFPDVTYF MVLRRSPSYY 240
  241 IFSLVIPSAF ITVVTIVGFF TPHSTTGENT EKVSLGVTAL LSMAIIMMMV SDEVPATSEV 300
  301 IPLIGKYYIG LIFLIFMAAF TTTLTLSYQM RGNSGQEVDP RVRDFFFYQI AANP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.09691
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [355-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CISWAFSFQL PKKLLRSDHR KQSFFFTNGA AHVNGYSKGA LHPNTPPAHI VKMEEITGGG  60
   61 SVKSFVMSQE SAATSTLLTS SLMKIKVVLD DMKASIHAER ELKRIKFEWQ QVTRLIDRCI 120
  121 MFSYILITIA FAMVMLASRD PPIVLNDLIM DSVKST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.045757
Match: 1oedB
Description: Acetylcholine receptor protein, beta chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle