YRC Public Data Repository - Protein Structure Prediction

Protein:	HDA10_ARATH
Organism:	Arabidopsis thaliana
Length:	142 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HDA10_ARATH.

Description	E-value	Query Range	Subject Range
gi\|151556584, gi... - gi\|151556584\|gb\|AAI48798.1\| Histone deacetylase 2 [synthetic construct], gi\|148922187\|gb\|AAI46377.1\|... gi\|116284376 - gi\|116284376\|ref\|NP_001518.2\| histone deacetylase 2 [Homo sapiens]	243.0	[0..3]	[140..369]
gi\|114608973 - gi\|114608973\|ref\|XP_518700.2\| PREDICTED: similar to HDAC2 protein [Pan troglodytes]	242.0	[0..3]	[140..368]
gi\|109510197, gi... - gi\|62666128\|ref\|XP_342150.2\| PREDICTED: similar to Histone deacetylase 2 (HD2) [Rattus norvegicus], ...	242.0	[0..3]	[140..396]
gi\|32450592 - gi\|32450592\|gb\|AAH54208.1\| Hdac2 protein [Xenopus laevis]	241.0	[0..3]	[140..275]
gi\|55716026, gi\|... - gi\|55716026\|gb\|AAH85375.1\| Histone deacetylase 1 [Danio rerio], gi\|182892182\|gb\|AAI65208.1\| Hdac1 pr...	239.0	[0..3]	[139..275]
gi\|49257716, gi\|... - gi\|53749670\|ref\|NP_001005432.1\| histone deacetylase 2 [Xenopus (Silurana) tropicalis], gi\|49257716\|g...	239.0	[0..3]	[140..275]
gi\|111305328, gi... - gi\|115495423\|ref\|NP_001068614.1\| histone deacetylase 2 [Bos taurus], gi\|111305328\|gb\|AAI20420.1\| His...	238.0	[0..3]	[140..275]

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Predicted Domain #1

Region A:
Residues: [1-142]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFSMLFTGH AECGGYTKEN VARCWTVETG ILLDTELPNE IPENDYIKYF APDFSLKIPG  60
   61 GHIENLNTKS YISSIKVQIL ENLRYIQHAP SVQMQEVPPD FYIPDFDEDE QNPDVRVDQR 120
  121 SRDKQIQRDD EYFDGDNDND AS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.69897
Match:	1t64A
Description:	Crystal Structure of human HDAC8 complexed with Trichostatin A
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits