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View Structure Prediction Details

Protein: CPSF3_ARATH
Organism: Arabidopsis thaliana
Length: 693 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CPSF3_ARATH.

Description E-value Query
Range
Subject
Range
gi|18377654 - gi|18377654|gb|AAL66977.1| putative cleavage and polyadenylation specificity factor [Arabidopsis tha...
560.0 [0..1] [693..1]
CPSF3_BOVIN - Cleavage and polyadenylation specificity factor subunit 3 OS=Bos taurus GN=CPSF3 PE=1 SV=1
544.0 [0..15] [688..5]
gi|194220982 - gi|194220982|ref|XP_001502516.2| PREDICTED: similar to Cleavage and Polyadenylation Specifity Factor...
gi|73979708 - gi|73979708|ref|XP_540075.2| PREDICTED: similar to Cleavage and polyadenylation specificity factor, ...
543.0 [0..15] [688..5]
gi|114576010, gi... - gi|114576010|ref|XP_001154730.1| PREDICTED: hypothetical protein isoform 8 [Pan troglodytes], gi|114...
541.0 [0..15] [688..5]
gi|49522504, gi|... - gi|55741994|ref|NP_001006770.1| cleavage and polyadenylation specific factor 3, 73kDa [Xenopus (Silu...
gi|55741994 - ref|NP_001006770.1| cleavage and polyadenylation specific factor 3, 73kDa [Xenopus tropicalis]
541.0 [0..4] [690..1]
gi|67969340 - gi|67969340|dbj|BAE01022.1| unnamed protein product [Macaca fascicularis]
540.0 [0..15] [688..5]
CPSF3 - cleavage and polyadenylation specific factor 3, 73kDa
540.0 [0..15] [688..5]
CPSF3_MOUSE - Cleavage and polyadenylation specificity factor subunit 3 OS=Mus musculus GN=Cpsf3 PE=1 SV=2
539.0 [0..15] [688..5]

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Predicted Domain #1
Region A:
Residues: [1-464]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSSTSLKR REQPISRDGD QLIVTPLGAG SEVGRSCVYM SFRGKNILFD CGIHPAYSGM  60
   61 AALPYFDEID PSSIDVLLIT HFHIDHAASL PYFLEKTTFN GRVFMTHATK AIYKLLLTDY 120
  121 VKVSKVSVED MLFDEQDINK SMDKIEVIDF HQTVEVNGIK FWCYTAGHVL GAAMFMVDIA 180
  181 GVRILYTGDY SREEDRHLRA AELPQFSPDI CIIESTSGVQ LHQSRHIREK RFTDVIHSTV 240
  241 AQGGRVLIPA FALGRAQELL LILDEYWANH PDLHNIPIYY ASPLAKKCMA VYQTYILSMN 300
  301 DRIRNQFANS NPFVFKHISP LNSIDDFNDV GPSVVMATPG GLQSGLSRQL FDSWCSDKKN 360
  361 ACIIPGYMVE GTLAKTIINE PKEVTLMNGL TAPLNMQVHY ISFSAHADYA QTSTFLKELM 420
  421 PPNIILVHGE ANEMMRLKQK LLTEFPDGNT KIMTPKNCES VEMY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 102.0
Match: 2i7tA
Description: No description for 2i7tA was found.

Predicted Domain #2
Region A:
Residues: [465-552]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FNSEKLAKTI GRLAEKTPDV GDTVSGILVK KGFTYQIMAP DELHVFSQLS TATVTQRITI  60
   61 PFVGAFGVIK HRLEKIFESV EFSTDEES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.730 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.730 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.571 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.512 a.138.1 Multiheme cytochromes
View Download 0.509 a.39.1 EF-hand
View Download 0.505 a.11.1 Acyl-CoA binding protein
View Download 0.452 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.452 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.429 d.52.9 Description not found.
View Download 0.397 a.39.1 EF-hand

Predicted Domain #3
Region A:
Residues: [553-693]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLPALKVHER VTVKQESEKH ISLQWSSDPI SDMVSDSIVA LILNISREVP KIVMEEEDAV  60
   61 KSEEENGKKV EKVIYALLVS LFGDVKLGEN GKLVIRVDGN VAQLDKESGE VESEHSGLKE 120
  121 RVRVAFERIQ SAVKPIPLSA S

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.799 N/A N/A d.129.6 Description not found.
View Download 0.678 N/A N/A d.129.6 Description not found.
View Download 0.566 N/A N/A c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.543 N/A N/A a.74.1 Cyclin-like
View Download 0.477 N/A N/A a.79.1 Antitermination factor NusB
View Download 0.474 N/A N/A a.26.1 4-helical cytokines
View Download 0.391 N/A N/A d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.386 N/A N/A a.74.1 Cyclin-like
View Download 0.384 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.369 N/A N/A b.55.1 PH domain-like
View Download 0.369 N/A N/A b.55.1 PH domain-like
View Download 0.355 N/A N/A a.26.1 4-helical cytokines
View Download 0.349 N/A N/A b.42.2 Ricin B-like lectins
View Download 0.295 N/A N/A a.36.1 Signal peptide-binding domain
View Download 0.290 N/A N/A d.144.1 Protein kinase-like (PK-like)


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle