YRC Public Data Repository - Protein Structure Prediction

Protein:	CLPX1_ARATH
Organism:	Arabidopsis thaliana
Length:	579 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLPX1_ARATH.

Description	E-value	Query Range	Subject Range
gi\|2674203 - gi\|2674203\|gb\|AAB88706.1\| CLP protease regulatory subunit CLPX [Arabidopsis thaliana]	427.0	[0..1]	[579..1]
CLPX_SILPO - ATP-dependent Clp protease ATP-binding subunit clpX OS=Silicibacter pomeroyi GN=clpX PE=3 SV=1 CLPX_RUEPO, CLPX... - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Silicibacter pomeroyi (strain ATCC 700808 / D...	341.0	[0..98]	[538..9]
gi\|76581159, gi\|... - gi\|76811706\|ref\|YP_333873.1\| ATP-dependent protease ATP-binding subunit [Burkholderia pseudomallei 1...	340.0	[0..95]	[538..47]
CLPX_THIDA - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Thiobacillus denitrificans (strain ATCC 25259...	336.0	[0..101]	[533..8]
gi\|84510700, gi\|... - gi\|84515417\|ref\|ZP_01002779.1\| ATP-dependent protease ATP-binding subunit [Loktanella vestfoldensis ...	336.0	[0..99]	[540..8]
CLPX_MAGSA - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Magnetospirillum magneticum (strain AMB-1 / A...	334.0	[0..98]	[539..7]
gi\|53719040, gi\|... - gi\|53719040\|ref\|YP_108026.1\| ATP-dependent protease ATP-binding subunit [Burkholderia pseudomallei K...	334.0	[0..95]	[538..11]
gi\|254730365 - gi\|254730365\|ref\|ZP_05188943.1\| ATP-dependent protease ATP-binding subunit ClpX [Brucella abortus bv... CLPX_BRUA2 - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Brucella abortus (strain 2308) GN=clpX PE=3 S... CLPX_BRUAB - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Brucella abortus biovar 1 (strain 9-941) GN=c... CLPX_BRUME - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Brucella melitensis biotype 1 (strain 16M / A... CLPX_BRUMB - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Brucella melitensis biotype 2 (strain ATCC 23... CLPX_BRUAB - ATP-dependent Clp protease ATP-binding subunit clpX OS=Brucella abortus GN=clpX PE=3 SV=2 gi\|254693819 - gi\|254693819\|ref\|ZP_05155647.1\| ATP-dependent protease ATP-binding subunit ClpX [Brucella abortus bv... CLPX_BRUME - ATP-dependent Clp protease ATP-binding subunit clpX OS=Brucella melitensis GN=clpX PE=3 SV=1 gi\|254697468 - gi\|254697468\|ref\|ZP_05159296.1\| ATP-dependent protease ATP-binding subunit ClpX [Brucella abortus bv... gi\|237815532, gi... - gi\|237815532\|ref\|ZP_04594529.1\| ATP-dependent Clp protease, ATP-binding subunit ClpX [Brucella abort... gi\|254689335 - gi\|254689335\|ref\|ZP_05152589.1\| ATP-dependent protease ATP-binding subunit ClpX [Brucella abortus bv...	333.0	[0..98]	[535..9]
CLPX_BRUSU - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Brucella suis biovar 1 (strain 1330) GN=clpX ... CLPX_BRUSI - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Brucella suis (strain ATCC 23445 / NCTC 10510... CLPX_BRUSU - ATP-dependent Clp protease ATP-binding subunit clpX OS=Brucella suis GN=clpX PE=3 SV=1	332.0	[0..98]	[535..9]
CLPX_BURMA - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Burkholderia mallei (strain ATCC 23344) GN=cl... CLPX_BURM9 - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Burkholderia mallei (strain NCTC 10229) GN=cl... CLPX_BURMA - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Burkholderia mallei GN=clpX PE=3 SV=1 gi\|243065059, gi... - gi\|243065059\|gb\|EES47245.1\| ATP-dependent Clp protease, ATP-binding subunit ClpX [Burkholderia malle... gi\|254177862, gi... - gi\|254177862\|ref\|ZP_04884517.1\| ATP-dependent Clp protease, ATP-binding subunit ClpX [Burkholderia m... gi\|67642017, gi\|... - gi\|67642017\|ref\|ZP_00440780.1\| ATP-dependent Clp protease, ATP-binding subunit ClpX [Burkholderia ma... CLPX_BURM7 - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Burkholderia mallei (strain NCTC 10247) GN=cl... CLPX_BURMS - ATP-dependent Clp protease ATP-binding subunit ClpX OS=Burkholderia mallei (strain SAVP1) GN=clpX PE... gi\|85067447 - gi\|85067447\|ref\|ZP_01028300.1\| COG1219: ATP-dependent protease Clp, ATPase subunit [Burkholderia mal... gi\|100265229, gi... - gi\|87316111\|ref\|ZP_01097131.1\| COG1219: ATP-dependent protease Clp, ATPase subunit [Burkholderia mal... gi\|194525648, gi... - gi\|83620495\|ref\|ZP_00930914.1\| COG1219: ATP-dependent protease Clp, ATPase subunit [Burkholderia mal... gi\|83625773, gi\|... - gi\|83625773\|ref\|ZP_00936002.1\| COG1219: ATP-dependent protease Clp, ATPase subunit [Burkholderia mal... gi\|100918487, gi... - gi\|67638871\|ref\|ZP_00437806.1\| COG1219: ATP-dependent protease Clp, ATPase subunit [Burkholderia mal...	332.0	[0..95]	[538..4]

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Predicted Domain #1

Region A:
Residues: [1-87]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAALRSNTS RETASLTLSH FRYFIFNRIH TARTATSPPH CNHRSKSDEK FPYKISSLGT  60
   61 SFLDNRGGGE RRNSTKCYAA QKKLSGV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.782	N/A	N/A	c.13.2	Anti-sigma factor antagonist SpoIIaa
View	Download	0.645	N/A	N/A	d.108.1	Acyl-CoA N-acyltransferases (Nat)
View	Download	0.614	N/A	N/A	a.76.1	Iron-dependent represor protein, dimerization domain
View	Download	0.511	N/A	N/A	a.24.9	alpha-catenin/vinculin
View	Download	0.503	N/A	N/A	a.142.1	PTS-regulatory domain, PRD
View	Download	0.503	N/A	N/A	a.142.1	PTS-regulatory domain, PRD
View	Download	0.460	N/A	N/A	a.24.9	alpha-catenin/vinculin
View	Download	0.447	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.440	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.379	N/A	N/A	d.68.3	SirA-like

Predicted Domain #2

Region A:
Residues: [88-142]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSSVVILSSQ GDPPDLWQPP GDGVSVRVNG SSVNLGRGGG GGGSSPGGPG NGTGS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.0
Match:	1ovxA
Description:	NMR structure of the E. coli ClpX chaperone zinc binding domain dimer
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [143-579]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSKEDCWGGS NLGSDFPTPK EICKGLNKFV IGQERAKKVL SVAVYNHYKR IYHESSQKRS  60
   61 AGETDSTAAK PADDDMVELE KSNILLMGPT GSGKTLLAKT LARFVNVPFV IADATTLTQA 120
  121 GYVGEDVESI LYKLLTVADY NVAAAQQGIV YIDEVDKITK KAESLNISRD VSGEGVQQAL 180
  181 LKMLEGTIVN VPEKGARKHP RGDNIQIDTK DILFICGGAF VDIEKTISER RHDSSIGFGA 240
  241 PVRANMRAGG VTNAAVASNL METVESSDLI AYGLIPEFVG RFPVLVSLSA LTENQLMQVL 300
  301 TEPKNALGKQ YKKMYQMNSV KLHFTESALR LIARKAITKN TGARGLRALL ESILMDSMYE 360
  361 IPDEGTGSDM IEAVVVDEEA VEGEGRRGSG AKILRGKGAL ARYLSETNSK DSPQTTKEGS 420
  421 DGETEVEAEI PSVVASM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	69.0
Match:	1um8A
Description:	Crystal structure of helicobacter pylori ClpX
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits