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View Structure Prediction Details

Protein: MPK8_ARATH
Organism: Arabidopsis thaliana
Length: 589 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MPK8_ARATH.

Description E-value Query
Range
Subject
Range
gi|110180200 - gi|110180200|gb|ABG54335.1| double HA-tagged mitogen activated protein kinase 8 [synthetic construct...
472.0 [0..1] [589..1]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGGGNLVDG VRRWLFQRPS SSSSSSSSNN NNNNHEQPIF NSSSFSSSSN PNHSANSGEL  60
   61 IIEEDLDFSG LTLINVPKRN HLPMDP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.522879
Match: 2fo0A
Description: No description for 2fo0A was found.

Predicted Domain #2
Region A:
Residues: [87-455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKKGETEFFT EYGEANRYQI QEVVGKGSYG VVASAVDSHT GERVAIKKIN DVFEHVSDAT  60
   61 RILREIKLLR LLRHPDVVEI KHIMLPPSRR EFRDIYVVFE LMESDLHQVI KANDDLTPEH 120
  121 YQFFLYQLLR GLKYVHAANV FHRDLKPKNI LANADCKLKI CDFGLARVSF NDAPTAIFWT 180
  181 DYVATRWYRA PELCGSFFSK YTPAIDIWSV GCIFAEMLLG KPLFPGKNVV HQLDLMTDFL 240
  241 GTPPPESISR IRNEKARRYL SSMRKKQPVP FSHKFPKADP LALRLLERLL AFDPKDRASA 300
  301 EDALADPYFS GLSNSEREPT TQPISKLEFD FERKKLVKDD VRELIYREIL EYHPQMLEEY 360
  361 LRGGDQLSF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.0
Match: 2baqA
Description: p38alpha bound to Ro3201195
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [456-589]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYPSGVDRFK RQFAHLEENQ GKPGAAGGGR STALHRHHAS LPRERVPAPN GETAEESSDV  60
   61 ERRAAAAVAS TLESEEADNG GGYSARNLMK SASISGSKCI GVQSKTDKED TIAEEEDNET 120
  121 VAELTDKVAS LHNS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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