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View Structure Prediction Details

Protein: VILI1_ARATH
Organism: Arabidopsis thaliana
Length: 909 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VILI1_ARATH.

Description E-value Query
Range
Subject
Range
VILI1_ARATH, VIL... - Villin-1 - Arabidopsis thaliana (Mouse-ear cress), (O81643) Villin 1
1050.0 [0..1] [909..1]

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Predicted Domain #1
Region A:
Residues: [1-735]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRLSKDIDS AFQGVGTKSG LEIWCVYNKQ LISIPKSSFG KFHSGNAYLV LRTFLRKIES  60
   61 PQYDIHYWLG IDANEVDSIL ASDKALDLDA ALGCCTVQYR EVQGQETEKF LSYFKPCIIP 120
  121 VEGKYSPKTG IAGETYQVTL LRCKGDHVVR VKEVPFLRSS LNHDDVFILD TASKVFLFAG 180
  181 CNSSTQEKAK AMEVVEYIKD NKHDGRCEVA TIEDGKFSGD SDAGEFWSFF GGYAPIPKLS 240
  241 SSTTQEQTQT PCAELFWIDT KGNLHPTGTS SLDKDMLEKN KCYMLDCHSE VFVWMGRNTS 300
  301 LTERKTSISS SEEFLRKEGR STTTSLVLLT EGLENARFRS FFNKWPQTVE SSLYNEGREK 360
  361 VAALFKQKGY DVEELPDEED DPLYTNCRDN LKVWRVDGDD VSLLSIPDQT KLFTGDCYLV 420
  421 QYKYTYKERT EHLLYVWIGC ESIQQDRADA ITNASAIVGT TKGESVLCHI YQGNEPSRFF 480
  481 PMFQSLVVFK GGLSRRYKVL LAEKEKIGEE YNENKASLFR VVGTSPRNMQ AIQVNLVATS 540
  541 LNSSYSYILQ YGASAFTWIG KLSSDSDHEV LDRMLYFLDT SCQPIYIREG NETDTFWNLL 600
  601 GGKSEYPKEK EMRKQIEEPH LFTCSCSSDV LKVKEIYNFV QDDLTTEDVF LLDCQSEVYV 660
  661 WIGSNSNIKS KEEALTLGLK FLEMDILEEG LTMRTPVYVV TEGHEPPFFT RFFEWVPEKA 720
  721 NMHGNSFERK LASLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 2fghA
Description: No description for 2fghA was found.

Predicted Domain #2
Region A:
Residues: [736-830]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKKTSTKRSS GSQYRSQSKD NASRDLQSRS VSSNGSERGV SPCSSEKLLS LSSAEDMTNS  60
   61 SNSTPVVKKL FSESLLVDPN DGVARQESSS KSDIS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [831-909]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQKPRVGINS DLSSLESLAY SYEQLRVDSQ KPVTDIDATR REAYLTEKEF EERFGMAKSE  60
   61 FYALPKWKQN KLKISLHLF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.522879
Match: 1ujsA
Description: Solution structure of the Villin headpiece domain of human actin-binding LIM protein homologue (KIAA0843 protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 5.53385110100387 bayes_pls_golite062009
cytoskeletal protein binding 4.11554260532242 bayes_pls_golite062009
binding 2.42849959483419 bayes_pls_golite062009
protein binding 1.84182032292601 bayes_pls_golite062009
PDZ domain binding 0.351516306039841 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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